A quality control system for ligand-binding assay of plasma renin activity: Proof-of-concept within a pharmacodynamic study

Autor: Läer, Stephanie, Breitkreutz, Jörg, Klingmann, Ingrid, Lagler, Florian, de Hoon, Jan, Dalinghaus, Michiel, Bajcetic, Milica, de Wildt, Saskia, Clarke, Anne Keatley, Breur, Johannes, Male, Christoph, Ablonczy, Laslo, Mir, Thomas, Vukomanovic, Vladislav, Dukic, Milan, Jovanovic, Ida, Burckhardt, Bjoern B., Cawello, Willi, Kleine, Karl, Moder, Angelika, Obarcanin, Emina, Wagner, Peter, Walsh, Jennifer, van Hecken, Anne, Spatenkova, Lucie, Ali, Mohsin, Božić, Bojana, Burdman, Maja Bijelić Ilja, Ciplea, Agnes, Faisal, Muhammad, Farahani, Samieh, Feickert, Martin, Gangnus, Tanja, Lazic, Milica, Makowski, Nina, Suessenbach, Fabian, van der Meulen, Marijke, Popović, Saša, Parezanović, Miro, Smeets, Nori, Swoboda, Vanessa, Bojanin, Dragana, Đorđević, Stefan, Dragić, Jasminka, Holle, Ann-Kathrin, Jovičić, Bosiljka, Košutić, Jovan, Kozomara, Gordana, Majid, Haidara, Mitrović, Jadranka, Ninić, Sanja, Parezanovic, Miro, Parezanovic, Vojislav, Pavlović, Andrija, Prijić, Sergej, Rebić, Branislava, Stefanović, Igor, Tordas, Daniel, Vulićević, Irena, Bartels, Anke, Čeko, Andjelka, Herborts, Marissa, Hennink, Annelies, Kosanović, Bosiljka, Kostic, Sanja, Isailović, Ljiljana, Maksimovic, Jasmina, Manai, Badies, Martinović, Nada, Máté, Gyöngyi, Perišić, Miloš, Reljić, Jelena, Salamomovic, Regina Pirker Marta, Schlesner, Claudia, Tins, Jutta, Wissmann, Eva, Suessenbach, Fabian Konstantin, Burckhardt, Bjoern Bengt

Publikováno v: In Journal of Pharmaceutical and Biomedical Analysis 20 March 2020 181

Relative Bioavailability of Enalapril Administered as Orodispersible Minitablets in Healthy Adults.

Autor: Van Hecken, Anne¹ (AUTHOR) anne.vanhecken@uzleuven.be, Burckhardt, Björn B.² (AUTHOR), Khalil, Feras² (AUTHOR), Hoon, Jan¹ (AUTHOR), Klingmann, Ingrid³ (AUTHOR), Herbots, Marissa¹ (AUTHOR), Laeer, Stephanie² (AUTHOR), Lagler, Florian B.⁴ (AUTHOR), Breitkreutz, Jörg⁵ (AUTHOR)

Publikováno v: Clinical Pharmacology in Drug Development. Feb2020, Vol. 9 Issue 2, p203-213. 11p.

[¹⁸F]MK-9470, a Positron Emission Tomography (PET) Tracer for in vivo Human PET Brain Imaging of the Cannabinoid-1 Receptor

Autor: Burns, H. Donald, Van Laere, Koen, Sanabria-Bohórquez, Sandra, Hamill, Terence G., Bormans, Guy, Eng, Wai-si, Gibson, Ray, Ryan, Christine, Connolly, Brett, Patel, Shil, Krause, Stephen, Vanko, Amy, Van Hecken, Anne, Dupont, Patrick, De Lepeleire, Inge, Rothenberg, Paul, Stoch, S. Aubrey, Cote, Josee, Hagmann, William K., Jewell, James P., Lin, Linus S., Liu, Ping, Goulet, Mark T., Gottesdiener, Keith, Wagner, John A., de Hoon, Jan, Mortelmans, Luc, Fong, Tung M., Hargreaves, Richard J.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2007 Jun 01. 104(23), 9800-9805.

Externí odkaz: https://www.jstor.org/stable/25427940

Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitablets

Autor: Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B, de Hoon, Jan, Laer, Stephanie, van Hecken, Anne, Herbort, Marissa, Breitkreutz, Joerg, Wiedey, Wolfgang, Klingmann, Ingrid, Spatenkova, Lucie, Lagler, Florian, Moder, Angelika, Khalil, Feras

Publikováno v: Frontiers in Pediatrics, Vol 7 (2019)
Frontiers in Pediatrics

Enalapril is recommended as the first line of therapy and is proven to improve survival rates for treatment of Pediatric Heart Failure; however, an approved drug and child appropriate dosage formulation is still absent. The present analysis was condu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca216c761278ef00d5c98d71bb9e7eaa
https://lirias.kuleuven.be/handle/123456789/640338

Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers

Autor: Postnov, Andrey, Schmidt, Mark E, Pemberton, Darrel J, de Hoon, Jan, Van Hecken, Anne, van den Boer, Maarten, Zannikos, Peter, van der Ark, Peter, Palmer, James A, Rassnick, Stef, Celen, Sofie, Bormans, Guy, Van Laere, Koen

Inhibition of fatty acid amide hydrolase (FAAH) potentiates endocannabinoid activity and is hypothesized to have therapeutic potential for mood and anxiety disorders and pain. The clinical profile of JNJ-42165279, an oral selective FAAH inhibitor, wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1131::cdf90589eca147ccb7c4aa0b881e5ead
https://lirias.kuleuven.be/handle/123456789/620513