Facile Generation of Heterotelechelic Poly(2-Oxazoline)s Towards Accelerated Exploration of Poly(2-Oxazoline)-Based Nanomedicine.

Autor: Van Guyse JFR; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA.; Leiden Academic Centre for Drug Research (LACDR), Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands., Abbasi S; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA., Toh K; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA., Nagorna Z; Leiden Academic Centre for Drug Research (LACDR), Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands., Li J; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA.; Institute for Materials Chemistry and Engineering, Kyushu University, 744 Motooka, Nishi-ku, 819-0395, Fukuoka, Japan., Dirisala A; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA., Quader S; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA., Uchida S; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA.; Department of Medical, Chemistry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 606-0823, Kyoto, Japan.; Department of Advanced Nanomedical Engineering, Medical Research Institute, Tokyo Medical and Dental University (TMDU), 113-8510, Tokyo, Japan., Kataoka K; Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, 210-0821, Kawasaki, Japan.; Present Adresses: S. A., Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, 21231, Baltimore, MD, USA.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Jul 01; Vol. 63 (27), pp. e202404972. Date of Electronic Publication: 2024 Jun 03.

Non-activated Esters as Reactive Handles in Direct Post-Polymerization Modification.

Autor: Van Guyse JFR; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium.; Leiden Academic Center for Drug Research (LACDR), Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands., Bernhard Y; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium.; Université de Lorraine, UMR CNRS 7053 L2CM, Faculté des Sciences et Technologies, BP 70239, 54506, Vandoeuvre-lès-Nancy Cedex, France., Podevyn A; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium., Hoogenboom R; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Oct 02; Vol. 62 (40), pp. e202303841. Date of Electronic Publication: 2023 Jul 03.

Stable amorphous solid dispersion of flubendazole with high loading via electrospinning.

Autor: Becelaere J; Ghent University, Center for Textile Science and Engineering, Faculty of Engineering and Architecture, Tech Lane Science Park 70A, B-9052 Ghent, Belgium., Van Den Broeck E; Ghent University, Center for Molecular Modeling, Faculty of Engineering and Architecture, Tech Lane Science Park 46, B-9052 Ghent, Belgium., Schoolaert E; Ghent University, Center for Textile Science and Engineering, Faculty of Engineering and Architecture, Tech Lane Science Park 70A, B-9052 Ghent, Belgium., Vanhoorne V; Ghent University, Laboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Van Guyse JFR; Ghent University, Supramolecular Chemistry Group, Faculty of Sciences, Krijgslaan 281-S4, B-9000 Ghent, Belgium., Vergaelen M; Ghent University, Supramolecular Chemistry Group, Faculty of Sciences, Krijgslaan 281-S4, B-9000 Ghent, Belgium., Borgmans S; Ghent University, Center for Molecular Modeling, Faculty of Engineering and Architecture, Tech Lane Science Park 46, B-9052 Ghent, Belgium., Creemers K; Ghent University, Center for Molecular Modeling, Faculty of Engineering and Architecture, Tech Lane Science Park 46, B-9052 Ghent, Belgium., Van Speybroeck V; Ghent University, Center for Molecular Modeling, Faculty of Engineering and Architecture, Tech Lane Science Park 46, B-9052 Ghent, Belgium. Electronic address: Veronique.VanSpeybroeck@UGent.be., Vervaet C; Ghent University, Laboratory of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Ottergemsesteenweg 460, B-9000 Ghent, Belgium. Electronic address: Chris.Vervaet@UGent.be., Hoogenboom R; Ghent University, Supramolecular Chemistry Group, Faculty of Sciences, Krijgslaan 281-S4, B-9000 Ghent, Belgium. Electronic address: Richard.Hoogenboom@UGent.be., De Clerck K; Ghent University, Center for Textile Science and Engineering, Faculty of Engineering and Architecture, Tech Lane Science Park 70A, B-9052 Ghent, Belgium. Electronic address: Karen.DeClerck@UGent.be.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2022 Nov; Vol. 351, pp. 123-136. Date of Electronic Publication: 2022 Sep 22.

Accelerated Post-Polymerization Amidation of Polymers with Side-Chain Ester Groups by Intramolecular Activation.

Autor: Van Guyse JFR; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium.; Present address: Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Leiske MN; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium., Verjans J; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium., Bernhard Y; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium.; Present address: Université de Lorraine, UMR CNRS 7053 L2CM, Faculté des Sciences et Technologies, BP 70239, 54506, Vandoeuvre-lès-Nancy Cedex, France., Hoogenboom R; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Jul 18; Vol. 61 (29), pp. e202201781. Date of Electronic Publication: 2022 May 25.

Enzymatically Transformable Polymersome-Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer.

Autor: Li J; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Ge Z; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.; School of Chemistry, Xi'an Jiaotong University, Xi'an, Shanxi, 710049, China., Toh K; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Liu X; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Dirisala A; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Ke W; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Wen P; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Zhou H; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Wang Z; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Xiao S; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China., Van Guyse JFR; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Tockary TA; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Xie J; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Gonzalez-Carter D; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Kinoh H; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Uchida S; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan., Anraku Y; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan.; Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan., Kataoka K; Innovation Center of Nanomedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki, 210-0821, Japan.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2021 Dec; Vol. 33 (49), pp. e2105254. Date of Electronic Publication: 2021 Oct 07.