Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.

Autor: Hopfner F; Department of Neurology Hannover Medical School, Hannover, Germany., Tietz AK; Department of Neurology, Kiel University, Kiel, Germany., Ruf VC; Center for Neuropathology and Prion Research, Ludwig-Maximilians-Universität, Munich, Germany., Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Department of Clinical Genomics, Mayo Clinic, Jacksonville, Florida, USA., Koga S; Department of Neuroscience (Neuropathology), Mayo Clinic, Jacksonville, Florida, USA., Dickson D; Department of Neuroscience (Neuropathology), Mayo Clinic, Jacksonville, Florida, USA., Aguzzi A; Institute of Neuropathology, University Hospital Zürich, Zürich, Switzerland., Attems J; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Beach T; Banner Sun Health Research Institute, Sun City, Arizona, USA., Beller A; Department of Pathology, University of Washington, Seattle, Washington, USA., Cheshire WP; Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA., van Deerlin V; Department of Pathology and Laboratory Medicine, Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Desplats P; Department of Neurosciences, School of Medicine University of California San Diego, La Jolla, California, USA.; Department of Pathology, School of Medicine University of California San Diego, La Jolla, California, USA., Deuschl G; Department of Neurology, Kiel University, Kiel, Germany., Duyckaerts C; Institut du Cerveau, UMR 7225, Sorbonne Université, Paris Brain Institute-ICM, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Inserm U1127 DMU Neurosciences, Paris, France.; Brainbank NeuroCEB Neuropathology Network: Plateforme de Ressources Biologiques, Hôpital de La Pitié-Salpêtrière, Bâtiment Roger Baillet, Paris Cedex, France., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel & University Hospital Schleswig-Holstein, Kiel, Germany., Evsyukov V; Department of Neurology Hannover Medical School, Hannover, Germany., Flanagan ME; Mesulam Center for Cognitive Neurology and Alzheimer's Disease Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.; Department of Pathology, Northwestern University, Chicago, Illinois, USA., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel & University Hospital Schleswig-Holstein, Kiel, Germany., Frosch MP; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA., Gearing M; Departments of Pathology and Laboratory Medicine and Neurology, Emory University School of Medicine, Atlanta, Georgia, USA., Gelpi E; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria.; Medical University of Vienna, Austrian Reference Center for Human Prion Diseases (OERPE), Vienna, Austria., van Gerpen JA; Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA., Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Glass JD; Department of Neurology, Emory University, Atlanta, Georgia, USA., Grinberg LT; Memory and Aging Center, Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, California, USA.; Global Health Institute, University of California, San Francisco, California, USA.; Department of Pathology, University of California, San Francisco, California, USA.; Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil., Halliday G; The University of Sydney, School of Medical Sciences, and Brain & Mind Centre, Sydney, New South Wales, Australia., Helbig I; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, New York, USA.; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Epilepsy NeuroGenetics Initiative (ENGIN), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Höllerhage M; Department of Neurology Hannover Medical School, Hannover, Germany., Huitinga I; Department of Neuroimmunology, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands.; Brain Plasticity Group, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, the Netherlands., Irwin DJ; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Keene DC; Department of Pathology, University of Washington, Seattle, Washington, USA., Kovacs GG; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria.; Department of Laboratory Medicine and Pathobiology and Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program and Krembil Brain Institute, University Health Network, Toronto, Ontario, Canada., Lee EB; Department of Pathology and Laboratory Medicine, Translational Neuropathology Research Laboratory Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Levin J; DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany., Martí MJ; Parkinson's Disease and Movement Disorders Unit, Department of Neurology, Hospital Clinic of Barcelona, Barcelona, Spain.; Institut de Neurociències, Maeztu Center, University of Barcelona, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain., Mackenzie I; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada., McKeith I; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Mclean C; Department of Anatomical Pathology, Alfred Health, Melbourne, Victoria, Australia., Mollenhauer B; Paracelsus-Elena-Klinik, Kassel, Germany.; Department of Neurology, University Medical Center Goettingen, Gottingen, Germany., Neumann M; Molecular Neuropathology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Tübingen, Germany.; Department of Neuropathology, University Hospital of Tübingen, Tübingen, Germany., Newell KL; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Pantelyat A; Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Pendziwiat M; Department of Neuropediatrics, Children's Hospital, University Medical Center Schleswig-Holstein, University of Kiel, Kiel, Germany.; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Molina Porcel L; Neurology Department, Hospital Clinic, IDIBAPS, Barcelona, Spain., Rabano A; Neuropathology Department, CIEN Foundation, Alzheimer's Centre Queen Sofía Foundation, Madrid, Spain., Matěj R; Department of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.; Department of Pathology and Molecular Medicine, 3rd Faculty of Medicine, Charles University, Thomayer University Hospital, Prague, Czech Republic., Rajput A; Division of Neurology, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Rajput A; Saskatchewan Movement Disorders Program, Saskatchewan Health Authority/University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Reimann R; Institute of Neuropathology, University Hospital Zürich, Zürich, Switzerland., Scott WK; John P. Hussman Institute for Human Genomics and Dr. John T. Macdonald Department of Human Genetics, University of Miami, Miller School of Medicine, Miami, Florida, USA., Seeley W; Memory and Aging Center, Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, California, USA.; Global Health Institute, University of California, San Francisco, California, USA.; Department of Pathology, University of California, San Francisco, California, USA., Selvackadunco S; Basic and Clinical Neuroscience Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Simuni T; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Stadelmann C; Institute for Neuropathology, University Medical Centre Göttingen, Göttingen, Germany., Svenningsson P; Section of Neurology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Thomas A; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Trenkwalder C; Paracelsus-Elena-Klinik, Kassel, Germany.; Department of Neurosurgery, University Medical Center Goettingen, Goettingen, Germany., Troakes C; Basic and Clinical Neuroscience Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Trojanowski JQ; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Uitti RJ; Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA., White CL; Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA., Xie T; Department of Neurology, University of Chicago Medicine, Chicago, Illinois, USA., Ximelis T; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain., Yebenes J; Neurological Tissue Bank, Biobanc-Hospital Clínic-IDIBAPS, Barcelona, Spain.; Servicio de Neurología, Hospital Ramón y Cajal de Madrid, Madrid, Spain., Müller U; Institute of Human Genetics, JLU-Gießen, Giessen, Germany., Schellenberg GD; Department of Pathology and Laboratory Medicine, Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Herms J; Center for Neuropathology and Prion Research, Ludwig-Maximilians-Universität, Munich, Germany.; DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Kuhlenbäumer G; Department of Neurology, Kiel University, Kiel, Germany., Höglinger G; Department of Neurology Hannover Medical School, Hannover, Germany.; DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.; Zentrum für Systemische Neurowissenschaften, Hannover, Germany.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2022 Oct; Vol. 37 (10), pp. 2110-2121. Date of Electronic Publication: 2022 Aug 23.

Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3.

Autor: Koike Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Jansen-West KR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Hanna Al-Shaikh R; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Carlomagno Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, 32224, USA., Song Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Dunmore JA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., LeDoux MS; University of Memphis, and Veracity Neuroscience LLC, Memphis, TN, 38152, USA., Friedman JH; Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI, 02906, USA., Pena AB; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Uitti RJ; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Zaremba J; Institute of Psychiatry and Neurology, Jana III Sobieskiego 9, 02-957, Warszawa, Poland., van Gerpen JA; University of Alabama at Birmingham, AL, 35233, USA., Pfeiffer RF; Department of Neurology, Oregon Health & Science University, Portland, OR, 97239, USA., Veerappan V; Department of Neurology, Oregon Health & Science University, Portland, OR, 97239, USA., Aiba I; Department of Neurology, National Hospital Organization, Higashinagoya National Hospital, Nagoya, Japan., Hashimoto R; Department of Neurology, National Hospital Organization, Higashinagoya National Hospital, Nagoya, Japan., Giles SS; Ascension Medical Group Saint Vincent's Spine and Brain Institute, Jacksonville, FL, 32204, USA., Shah JS; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Tipton PW; Department of Neurology, Mayo Clinic, Rochester, MN, 55905, USA., Huang JF; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Wierenga KJ; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Aasly J; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Fryer JD; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, 32224, USA; Department of Neuroscience, Mayo Clinic, Scottsdale, AZ, 85259, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, 32224, USA., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA. Electronic address: wszolek.zbigniew@mayo.edu., Prudencio M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, 32224, USA. Electronic address: prudencio.mercedes@mayo.edu.

Publikováno v: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2021 Aug; Vol. 89, pp. 151-154. Date of Electronic Publication: 2021 Jul 17.

Distinct patterns of white matter hyperintensity and cortical thickness of CSF1R-related leukoencephalopathy compared with subcortical ischemic vascular dementia.

Autor: Kim, Seung Joo^1,2 (AUTHOR), Cho, Wanzee³ (AUTHOR), Kim, Hee Jin^2,4,5 (AUTHOR), Na, Duk L.^2,4 (AUTHOR), Seo, Sang Won^2,4,5 (AUTHOR), Jung, Na-Yeon⁶ (AUTHOR), Lee, Jae-Hyeok^6,7 (AUTHOR), Lee, Myung Jun⁸ (AUTHOR), Kang, Heeyoung⁹ (AUTHOR), Seong, Joon-Kyung^3,10 (AUTHOR), Kim, Eun-Joo⁸ (AUTHOR) eunjookim@pusan.ac.kr

Publikováno v: PLoS ONE. 10/7/2024, Vol. 19 Issue 10, p1-15. 15p.

Blood–brain barrier breakdown in dementia with Lewy bodies.

Autor: Gan, Jinghuan¹ (AUTHOR), Xu, Ziming² (AUTHOR), Chen, Zhichao¹ (AUTHOR), Liu, Shuai³ (AUTHOR), Lu, Hao⁴ (AUTHOR), Wang, Yajie² (AUTHOR), Wu, Hao³ (AUTHOR), Shi, Zhihong³ (AUTHOR), Chen, Huijun² (AUTHOR), Ji, Yong³ (AUTHOR) jiyongusa@126.com

Publikováno v: Fluids & Barriers of the CNS. 9/17/2024, Vol. 21 Issue 1, p1-13. 13p.

Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study.

Autor: Pan, Jie¹ (AUTHOR), Fores-Martos, Jaume¹ (AUTHOR), Delpirou Nouh, Claire² (AUTHOR), Jensen, Tanner D.² (AUTHOR), Vallejo, Kristen¹ (AUTHOR), Cayrol, Romain³ (AUTHOR), Ahmadian, Saman⁴ (AUTHOR), Ashley, Euan A.^1,5,6 (AUTHOR), Greicius, Michael D.² (AUTHOR), Cobos, Inma¹ (AUTHOR) icobos@stanford.edu

Publikováno v: Acta Neuropathologica Communications. 9/3/2024, Vol. 12 Issue 1, p1-21. 21p.