Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival

Autor: Van Esch, Edith M.G., Van Poelgeest, Mariette I.E., Kouwenberg, Simone, Osse, E. Michelle, Trimbos, J. Baptist M.Z., Fleuren, Gert Jan, Jordanova, Ekaterina S., Van Der Burg, Sjoerd H.

Publikováno v: International Journal of Cancer, 136(4), E95-E106. Wiley-Liss Inc.
Van Esch, E M G, Van Poelgeest, M I E, Kouwenberg, S, Osse, E M, Trimbos, J B M Z, Fleuren, G J, Jordanova, E S & Van Der Burg, S H 2016, ' Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival ', International Journal of Cancer, vol. 136, no. 4, pp. E95-E106 . https://doi.org/10.1002/ijc.29174

Human papillomavirus-induced usual-type vulvar intraepithelial neoplasia (uVIN) are infiltrated by immune cells but apparently not cleared. A potential explanation for this is an impaired T cell effector function by an immunesuppressive milieu, coinf

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https://research.vumc.nl/en/publications/ed35f961-39c4-4fb2-a9bd-8e798d7df35a

Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival.

Autor: van Esch, Edith M.G., van Poelgeest, Mariette I.E., Kouwenberg, Simone, Osse, E. Michelle, Trimbos, J. Baptist M.Z., Fleuren, Gert Jan, Jordanova, Ekaterina S., van der Burg, Sjoerd H.

Publikováno v: International Journal of Cancer; Feb2015, Vol. 136 Issue 4, pE95-E106, 12p