Zobrazeno 1 - 10
of 645
pro vyhledávání: '"Van Eldik Linda J"'
Autor:
Frazier, Hilaree N., Braun, David J., Bailey, Caleb S., Coleman, Meggie J., Davis, Verda A., Dundon, Stephen R., McLouth, Christopher J., Muzyk, Hana C., Powell, David K., Rogers, Colin B., Roy, Saktimayee M., Van Eldik, Linda J.
Publikováno v:
In Brain, Behavior, & Immunity - Health October 2024 40
Publikováno v:
BMC Neuroscience, Vol 9, Iss Suppl 2, p S12 (2008)
Abstract Protein kinases are critical modulators of a variety of cellular signal transduction pathways, and abnormal phosphorylation events can be a cause or contributor to disease progression in a variety of disorders. This has led to the emergence
Externí odkaz:
https://doaj.org/article/e97da5ba6d9d413dbb00cbb7f55a9ca4
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 84 (2011)
Abstract Background The p38α MAPK isoform is a well-established therapeutic target in peripheral inflammatory diseases, but the importance of this kinase in pathological microglial activation and detrimental inflammation in CNS disorders is less wel
Externí odkaz:
https://doaj.org/article/88094d55827c460d98031cd9bfce2674
Autor:
Watterson D Martin, Dimayuga Edgardo R, de Almeida Lucia, Xing Bin, Bachstetter Adam D, Van Eldik Linda J
Publikováno v:
Journal of Neuroinflammation, Vol 8, Iss 1, p 79 (2011)
Abstract Background Overproduction of proinflammatory cytokines from activated microglia has been implicated as an important contributor to pathophysiology progression in both acute and chronic neurodegenerative diseases. Therefore, it is critical to
Externí odkaz:
https://doaj.org/article/7bda3b339a0647aaac126af0eee43e6c
Publikováno v:
Journal of Neuroinflammation, Vol 5, Iss 1, p 35 (2008)
Abstract Background An endotoxin insult mimics a severe peripheral infection and recent evidence suggests that a single exposure can cause long-term cognitive deficits. A peripheral injection of LPS results in production of pro-inflammatory cytokines
Externí odkaz:
https://doaj.org/article/e06fc07d1321493cb627a71b5f8e1c66
Publikováno v:
Journal of Neuroinflammation, Vol 5, Iss 1, p 28 (2008)
Abstract Background Traumatic brain injury (TBI) with its associated morbidity is a major area of unmet medical need that lacks effective therapies. TBI initiates a neuroinflammatory cascade characterized by activation of astrocytes and microglia, an
Externí odkaz:
https://doaj.org/article/c7199af291544908b0d1651fb8c557cc
Autor:
McNamara Laurie K, Craft Jeffrey M, Hu Wenhui, Roy Saktimayee M, Ranaivo Hantamalala, Munoz Lenka, Chico Laura, Van Eldik Linda J, Watterson D Martin
Publikováno v:
Journal of Neuroinflammation, Vol 4, Iss 1, p 21 (2007)
Abstract Background An accumulating body of evidence is consistent with the hypothesis that excessive or prolonged increases in proinflammatory cytokine production by activated glia is a contributor to the progression of pathophysiology that is causa
Externí odkaz:
https://doaj.org/article/3d2d1aac66a242b8be1a4529690d5771
Publikováno v:
Journal of Neuroinflammation, Vol 2, Iss 1, p 15 (2005)
Abstract Background Interleukin 1 (IL-1) is a key mediator of immune responses in health and disease. Although classically the function of IL-1 has been studied in the systemic immune system, research in the past decade has revealed analogous roles i
Externí odkaz:
https://doaj.org/article/8ed28ef3d1934602aa49d21115e8d206
Autor:
Van Eldik, Linda J., Siemers, Eric R., Collins, Emily C., Gold, Michael, Henley, David, Johannsen, Peter, Möbius, Hans J., Shulman, Melanie, Zhou, Jin, Carrillo, Maria, Weber, Christopher
Publikováno v:
Alzheimer's & Dementia: Translational Research & Clinical Interventions; Oct2024, Vol. 10 Issue 4, p1-8, 8p
Autor:
Bachstetter, Adam D., Morganti, Josh M., Bodnar, Colleen N., Webster, Scott J., Higgins, Emma K., Roberts, Kelly N., Snider, Henry, Meier, Shelby E., Nation, Grant K., Goulding, Danielle S., Hamm, Matthew, Powell, David K., Vandsburger, Moriel, Van Eldik, Linda J., Abisambra, Jose F.
Publikováno v:
In Experimental Neurology April 2020 326