Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Van Du T, Tran"'
Autor:
Anna Niarakis, Reinhard Laubenbacher, Gary An, Yaron Ilan, Jasmin Fisher, Åsmund Flobak, Kristin Reiche, María Rodríguez Martínez, Liesbet Geris, Luiz Ladeira, Lorenzo Veschini, Michael L. Blinov, Francesco Messina, Luis L. Fonseca, Sandra Ferreira, Arnau Montagud, Vincent Noël, Malvina Marku, Eirini Tsirvouli, Marcella M. Torres, Leonard A. Harris, T. J. Sego, Chase Cockrell, Amanda E. Shick, Hasan Balci, Albin Salazar, Kinza Rian, Ahmed Abdelmonem Hemedan, Marina Esteban-Medina, Bernard Staumont, Esteban Hernandez-Vargas, Shiny Martis B, Alejandro Madrid-Valiente, Panagiotis Karampelesis, Luis Sordo Vieira, Pradyumna Harlapur, Alexander Kulesza, Niloofar Nikaein, Winston Garira, Rahuman S. Malik Sheriff, Juilee Thakar, Van Du T. Tran, Jose Carbonell-Caballero, Soroush Safaei, Alfonso Valencia, Andrei Zinovyev, James A. Glazier
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Digital twins represent a key technology for precision health. Medical digital twins consist of computational models that represent the health state of individual patients over time, enabling optimal therapeutics and forecasting patient prog
Externí odkaz:
https://doaj.org/article/c925f2072b8448f08b5b01c6a74dc959
Autor:
Abigail C. Lay, Van Du T. Tran, Viji Nair, Virginie Betin, Jennifer A. Hurcombe, Alexandra F. Barrington, Robert JP Pope, Frédéric Burdet, Florence Mehl, Dmytro Kryvokhyzha, Abrar Ahmad, Matthew C. Sinton, Philip Lewis, Marieangela C. Wilson, Rajasree Menon, Edgar Otto, Kate J. Heesom, Mark Ibberson, Helen C. Looker, Robert G. Nelson, Wenjun Ju, Matthias Kretzler, Simon C. Satchell, Maria F. Gomez, Richard J. M. Coward, BEAt-DKD consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Diabetic kidney disease (DKD) is the leading cause of end stage kidney failure worldwide, of which cellular insulin resistance is a major driver. Here, we study key human kidney cell types implicated in DKD (podocytes, glomerular endothelial
Externí odkaz:
https://doaj.org/article/b623e2a205714bcbbfbb61ff109ce900
Autor:
Shiying Li, Iulian Dragan, Van Du T. Tran, Chun Ho Fung, Dmitry Kuznetsov, Michael K. Hansen, Joline W. J. Beulens, Leen M. ‘t Hart, Roderick C. Slieker, Louise A. Donnelly, Mathias J. Gerl, Christian Klose, Florence Mehl, Kai Simons, Petra J. M. Elders, Ewan R. Pearson, Guy A. Rutter, Mark Ibberson
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionType 2 diabetes (T2D) onset, progression and outcomes differ substantially between individuals. Multi-omics analyses may allow a deeper understanding of these differences and ultimately facilitate personalised treatments. Here, in an unsu
Externí odkaz:
https://doaj.org/article/8020ce5607d8402da7325136b175bf1e
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1285-1303 (2022)
Candida species are the most commonly isolated opportunistic fungal pathogens in humans. Candida albicans causes most of the diagnosed infections, closely followed by Candida glabrata. C. albicans is well studied, and many genes have been shown to be
Externí odkaz:
https://doaj.org/article/74a33367f5fa4f2bb49f49b804477f95
Autor:
Carl Delfin, Iulian Dragan, Dmitry Kuznetsov, Juan Fernandez Tajes, Femke Smit, Daniel E. Coral, Ali Farzaneh, André Haugg, Andreas Hungele, Anne Niknejad, Christopher Hall, Daan Jacobs, Diana Marek, Diane P. Fraser, Dorothee Thuillier, Fariba Ahmadizar, Florence Mehl, Francois Pattou, Frederic Burdet, Gareth Hawkes, Ilja C. W. Arts, Jordi Blanch, Johan Van Soest, José-Manuel Fernández-Real, Juergen Boehl, Katharina Fink, Marleen M. J. van Greevenbroek, Maryam Kavousi, Michiel Minten, Nicole Prinz, Niels Ipsen, Paul W. Franks, Rafael Ramos, Reinhard W. Holl, Scott Horban, Talita Duarte-Salles, Van Du T. Tran, Violeta Raverdy, Yenny Leal, Adam Lenart, Ewan Pearson, Thomas Sparsø, Giuseppe N. Giordano, Vassilios Ioannidis, Keng Soh, Timothy M. Frayling, Carel W. Le Roux, Mark Ibberson
Publikováno v:
Life, Vol 14, Iss 2, p 262 (2024)
Obesity is considered by many as a lifestyle choice rather than a chronic progressive disease. The Innovative Medicines Initiative (IMI) SOPHIA (Stratification of Obesity Phenotypes to Optimize Future Obesity Therapy) project is part of a momentum sh
Externí odkaz:
https://doaj.org/article/343e0c783d8e4fc48237db8466dd4363
Autor:
Karina Barreiro, Abigail C. Lay, German Leparc, Van Du T. Tran, Marcel Rosler, Lusyan Dayalan, Frederic Burdet, Mark Ibberson, Richard J. M. Coward, Tobias B. Huber, Bernhard K. Krämer, Denis Delic, Harry Holthofer
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EV) are membranous particles secreted by all cells and found in body fluids. Established EV contents include a variety of RNA species, proteins, lipids and metabolites that are considered to reflect the physiological
Externí odkaz:
https://doaj.org/article/6c45737f12364881b6e1bf461d8da207
Autor:
Christina Lemberg, Kontxi Martinez de San Vicente, Ricardo Fróis-Martins, Simon Altmeier, Van Du T Tran, Sarah Mertens, Sara Amorim-Vaz, Laxmi Shanker Rai, Christophe d'Enfert, Marco Pagni, Dominique Sanglard, Salomé LeibundGut-Landmann
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010012 (2022)
As part of the human microbiota, the fungus Candida albicans colonizes the oral cavity and other mucosal surfaces of the human body. Commensalism is tightly controlled by complex interactions of the fungus and the host to preclude fungal elimination
Externí odkaz:
https://doaj.org/article/ea475c2029344f62836465862b55c7b8
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 8, Pp 2413-2426 (2017)
Candida glabrata is an important fungal pathogen which develops rapid antifungal resistance in treated patients. It is known that azole treatments lead to antifungal resistance in this fungal species and that multidrug efflux transporters are involve
Externí odkaz:
https://doaj.org/article/c11296e59ad048a4a9b56d79cafef646
Autor:
Florian R. Kirchner, Katharina Littringer, Simon Altmeier, Van Du T. Tran, Franziska Schönherr, Christina Lemberg, Marco Pagni, Dominique Sanglard, Nicole Joller, Salomé LeibundGut-Landmann
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Controlled immune activation in response to commensal microbes is critical for the maintenance of stable colonization and prevention of microbial overgrowth on epithelial surfaces. Our understanding of the host mechanisms that regulate bacterial comm
Externí odkaz:
https://doaj.org/article/f874fa79b0e246dcaa708ea4b03738b9
Publikováno v:
Virulence. 13(1)