Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): Study protocol for a trial within a cohort study

Autor: Schraa, S. J., Van Rooijen, K. L., Van Der Kruijssen, D. E.W., Rubio Alarcón, C., Phallen, J., Sausen, M., Simmons, J., Coupé, V. M.H., Van Grevenstein, W. M.U., Elias, S., Verkooijen, H. M., Laclé, M. M., Bosch, L. J.W., Van Den Broek, D., Meijer, G. A., Velculescu, V. E., Fijneman, R. J.A., Vink, G. R., Koopman, M., Dunker, Mich S., Lutke Holzik, Martijn F., Hoekstra, Ronald, Sommeijer, Dirkje W., Van Der Bilt, Jarmila D.W., Consten, Esther C.J., Cirkel, Geert A., Burghgraef, Thijs A., Van Der Schans, Emma M., Nieboer, Peter, Rietbroek, Ron C., Dekker, Jan Willem T., Verschoor, Arjan J., Talsma, Koen A.K., Brosens, Rebecca P.M., Helgason, Helgi H., Marinelli, Andreas W.K.S., De Hingh, Ignace H.J.T., Oldenhuis, Corina N., Jansen, Jan, Van Halteren, Henk K., Stockmann, Hein B.A.C., Beeker, Aart, Bosscha, Koop, Pruijt, Hans F.M., Spierings, Leontine E.A.M.M., Valkenburg-Van Iersel, Liselot B.J., Vles, Wouter J., De Jongh, Felix E., Van Cruijsen, Hester, Heikens, Joost T., Zimmerman, David D.E., Van Alphen, Robert J., Schiphorst, Anandi H.W., Van Leeuwen-Snoeks, Lobke L., Vogelaar, Jeroen F.J., Peters, Natascha A.J.B.

Publikováno v: BMC Cancer, 20(1):790. BioMed Central
BMC Cancer, 20(1):790. BMC
BMC Cancer
Schraa, S J, Van Rooijen, K L, Van Der Kruijssen, D E W, Rubio Alarcón, C, Phallen, J, Sausen, M, Simmons, J, Coupé, V M H, Van Grevenstein, W M U, Elias, S, Verkooijen, H M, Laclé, M M, Bosch, L J W, Van Den Broek, D, Meijer, G A, Velculescu, V E, Fijneman, R J A, Vink, G R, Koopman, M, Dunker, M S, Lutke Holzik, M F, Hoekstra, R, Sommeijer, D W, Van Der Bilt, J D W, Consten, E C J, Cirkel, G A, Burghgraef, T A, Van Der Schans, E M, Nieboer, P, Rietbroek, R C, Dekker, J W T, Verschoor, A J, Talsma, K A K, Brosens, R P M, Helgason, H H, Marinelli, A W K S, De Hingh, I H J T, Oldenhuis, C N, Jansen, J, Van Halteren, H K, Stockmann, H B A C, Beeker, A, Bosscha, K, Pruijt, H F M, Spierings, L E A M M, Valkenburg-Van Iersel, L B J, Vles, W J, De Jongh, F E, Van Cruijsen, H, Heikens, J T, Zimmerman, D D E, Van Alphen, R J, Schiphorst, A H W, Van Leeuwen-Snoeks, L L, Vogelaar, J F J & Peters, N A J B 2020, ' Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE) : Study protocol for a trial within a cohort study ', BMC Cancer, vol. 20, no. 1, 790 . https://doi.org/10.1186/s12885-020-07252-y
BMC Cancer, 20(1):790. BioMed Central Ltd
BMC cancer, 20(1):790. BioMed Central
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)

Background Accurate detection of patients with minimal residual disease (MRD) after surgery for stage II colon cancer (CC) remains an urgent unmet clinical need to improve selection of patients who might benefit form adjuvant chemotherapy (ACT). Pres

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https://research.vumc.nl/en/publications/8b8e8f3b-daeb-4c5b-a990-04e398b497c4

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