Comprehensive dissection of prevalence rates, sex differences, and blood level-dependencies of clozapine-associated adverse drug reactions

Autor: Müderrisoğlu, Ahmet, Privat, Alba Toll, Bouhuis, Alde, Hasan, Alkomiet, Jongkind, Amy, Gonzalez-Pinto, Ana, Santacana, Anna Mane, D'Agostino, Armando, Ertugrul, Aygün, Yağcioğlu, Ayşe Elif Anil, Crespo-Facorro, Benedicto, Sanchez-Barbero, Bianca, Spuch, Carlos, Morgenroth, Carla Lou, de Pinedo, Carmen Fernandez, Casetta, Cecilia, Bousman, Chad, Pantelis, Christos, Ovejas-Catalán, Claudia, Garcia-Rizo, Clemente, Okhuijsen-Pfeifer, Cynthia, Cohen, Dan, Ristic, Dragana Ignjatovic, Beld, Edwin, Repo-Tiihonen, Eila, Wagner, Elias, Jeger-Land, Ellen, Vilella, Elisabet, Bekema, Erwin, Sepúlveda, Stevan, Seghi, Federico, Wiedenmann, Federico, Martini, Francesca, Serio, Francesca, Vairano, Francesca, Mercuriali, Giacomo, Boido, Giovanni, Yoca, Gökhan, van Beek, Hanneke, Gijsman, Harm, Tuppurainen, Heli, Everall, Ian, Novakovic, Ivona, Zorrilla, Inaki, Erdoğan, Ibrahim Mert, Sapienza, Jacopo, Bogers, Jan, Tiihonen, Jari, Vázquez-Bourgon, Javier, van Os, Jim, Schneider-Thoma, Johannes, Luykx, Jurjen, Grootens, Koen, Mar-Barrutia, Lorea, Martorell, Lourdes, Bak, Maarten, Spangaro, Marco, de Vos, Marije, de Koning, Mariken, Garriga, Marina, Lähteenvuo, Markku, Bosia, Marta, van der Horst, Marte, Babaoğlu, Melih Önder, Veereschild, Mike, Manchia, Mirko, Edlinger, Monika, Fuentes-Pérez, Paloma, Paribello, Pasquale, Lopez-Pena, Purificacion, Kahn, René, Cavallaro, Roberto, Veerman, Selene, Gutwinski, Stefan, Schreiter, Stefanie, Ripke, Stephan, Baltanás, Tania Rivera, Oviedo-Salcedo, Tatiana, Hallikainen, Tero, Görlitz, Thomas, Alink, Wouter, Ayhan, Yavuz, van der Horst, Marte Z., Meijer, Yoeki, de Boer, Nini, Guloksuz, Sinan, Siskind, Dan, Luykx, Jurjen J.

Publikováno v: In Psychiatry Research December 2023 330

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Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia

Autor: Lin, Bochao D., Pinzón-Espinosa, Justo, Blouzard, Elodie, Van Der Horst, Marte Z., Okhuijsen-pfeifer, Cynthia, Van Eijk, Kristel R., Guloksuz, Sinan, Peyrot, Wouter J., Luykx, Jurjen J., Hasan, Alkomiet, Wagner, Elias, Pantelis, Christos, Everall, Ian P., Ayhan, Y., Babaoğlu, M. O., Bak, Maarten, Alink, Wouter, Beld, E, Bouhuis, A, Edlinger, M, Erdoğan, I .m., Gutwinski, Stefan, Hallikainen, Tero, Jeger-land, E, Lähteenvuo, Markku, De Koning, Mariken B., Morgenroth, Carla, Müderrisoğlu, A., Oviedo-salcedo, Tatiana, Schreiter, Stefanie, Repo-tiihonen, Eila, Tuppurainen, Heli, Veereschild, Mike, Veerman, Selene R.t., Cohen, Dan, De Vos, M, Bogers, Jan P.a.m., Anıl Yağcıoğlu, A.e., Tiihonen, Jari, Ripke, Stephan, Bousman, Chad A., Van Beek, H, Van Der Horst, Marte, Van Eijk, Kristel, Ertuğrul, A., Yoca, G., Görlitz, T., Grootens, K., Leucht, Stefan, Narang, A., Schneider-thoma, J., Kahn, René S., Bekema, Erwin, Kleymann, Phillip, Alizadeh, Behrooz Z., Van Amelsvoort, Therese, Cahn, Wiepke, De Haan, Lieuwe, Schirmbeck, Frederike, Simons, Claudia J.p., Van Os, Jim, Rutten, Bart, Van Winkel, Ruud

Publikováno v: JAMA Psychiatry. American Medical Association
Genetic Risk and Outcome of Psychosis (GROUP) and Clozapine International Consortium (CLOZIN) Investigators 2023, ' Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia ', JAMA Psychiatry, vol. 80, no. 2, pp. 181-185 . https://doi.org/10.1001/jamapsychiatry.2022.4234
JAMA psychiatry, 80(2), 181-185. American Medical Association
JAMA Psychiatry, 80(2), 181-185. American Medical Association
Genetic Risk and Outcome of Psychosis (GROUP) and Clozapine International Consortium (CLOZIN) Investigators 2023, ' Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia ', JAMA psychiatry, vol. 80, no. 2, pp. 181-185 . https://doi.org/10.1001/jamapsychiatry.2022.4234

ImportancePredictors consistently associated with psychosis liability and course of illness in schizophrenia (SCZ) spectrum disorders (SSD), including the need for clozapine treatment, are lacking. Longitudinally ascertained medication use may empowe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b30808f0062dc9476f2ac63918f219
http://www.scopus.com/inward/record.url?scp=85147317982&partnerID=8YFLogxK

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