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Staphylococcal complement evasion protein Sbi stabilises C3d dimers by inducing an N-terminal helix swap

Autor: Dunphy, Rhys, Wahid, Ayla, Back, Catherine, Martin, Beccie, Watts, Andrew, Dodson, Charlotte, Crennell, Susan, Van Den Elsen, Jean

Publikováno v: Dunphy, R, Wahid, A, Back, C, Martin, B, Watts, A, Dodson, C, Crennell, S & Van Den Elsen, J 2022, ' Staphylococcal complement evasion protein Sbi stabilises C3d dimers by inducing an N-terminal helix swap ', Frontiers in Immunology .

Staphylococcus aureus is an opportunistic pathogen that is able to thwart an effective host immune response by producing a range of immune evasion molecules, including S. aureus binder of IgG (Sbi) which interacts directly with the central complement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1378::67588c64878378d4cd7fa5ad07e548fa
https://purehost.bath.ac.uk/ws/files/235770371/Frontiers_in_Immunology_accepted_manuscript_2022.pdf

A Crystal Structure of the Complex Between Human Complement Receptor 2 and Its Ligand C3d

Autor: van den Elsen, Jean M. H., Isenman, David E.

Publikováno v: Science, 2011 Apr . 332(6029), 608-611.

Externí odkaz: http://dx.doi.org/10.1126/science.1201954

A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d

Autor: Clark, Elizabeth A., Crennell, Susan, Upadhyay, Abhishek, Zozulya, Alexey V., Mackay, Julia D., Svergun, Dmitri I., Bagby, Stefan, van den Elsen, Jean M.H.

Publikováno v: In Molecular Immunology January 2011 48(4):452-462

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