Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice

Autor: Van Der Wal, S. E.I., Vaneker, M., Kox, M., Braak, G., Van Hees, H. W.H., Van Den Brink, I. A., Van De Pol, F. M., Heunks, L. M., Van Der Hoeven, J. G., Joosten, L. A.B., Vissers, K. C.P., Scheffer, G. J.

Publikováno v: Acta Anaesthesiologica Scandinavica, 58(4), 487-494. Blackwell Munksgaard
Van Der Wal, S E I, Vaneker, M, Kox, M, Braak, G, Van Hees, H W H, Van Den Brink, I A, Van De Pol, F M, Heunks, L M, Van Der Hoeven, J G, Joosten, L A B, Vissers, K C P & Scheffer, G J 2014, ' Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice ', Acta Anaesthesiologica Scandinavica, vol. 58, no. 4, pp. 487-494 . https://doi.org/10.1111/aas.12276

Background Mechanical ventilation (MV) can result in inflammation and subsequent lung injury. Toll-like receptor (TLR)4 and NF-κB are proposed to play a crucial role in the MV-induced inflammatory response. Resveratrol (RVT) exhibits anti-inflammato

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Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice.

Autor: Van der Wal SE; Department of Anesthesiology, Radboud University Nijmegen Medical Centre (RUNMC), Nijmegen, The Netherlands., Vaneker M, Kox M, Braak G, Van Hees HW, Van den Brink IA, Van de Pol FM, Heunks LM, Van der Hoeven JG, Joosten LA, Vissers KC, Scheffer GJ

Publikováno v: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2014 Apr; Vol. 58 (4), pp. 487-94. Date of Electronic Publication: 2014 Feb 24.