Effects of interrupting residues on DNA dumbbell structures formed by CCTG tetranucleotide repeats associated with myotonic dystrophy type 2.

Autor: Yang Y; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences, China., Wang Y; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences, China.; School of Materials Science and Engineering, Tianjin University, China., Yan Z; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences, China., Li Z; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China., Guo P; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences, China.

Publikováno v: FEBS letters [FEBS Lett] 2024 Oct; Vol. 598 (20), pp. 2544-2556. Date of Electronic Publication: 2024 Jun 25.

Stereoselective Transformations on d-Glucose-Derived Eight-Membered Ring Carbocycles

Autor: van der Marel Ga, van Hooft Pa, van Boom Jh, Remy E. J. N. Litjens, van Boeckel Ca

Publikováno v: Organic Letters. 3:731-733

The cyclooctenol derivative 1 can be transformed into the nine-membered ring lactone 3, as well as the amino-containing carbocycles 4 and 5. The corresponding ketone 2 gives access to the conformationally locked azasugar 6.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::993786d42e121668966f9c5e851ebf3c
https://doi.org/10.1021/ol007047+

The First Solid-Phase Synthesis of a Peptide-Tethered Platinum(II) Complex This research was supported by the Council for Chemical Sciences of The Netherlands Organization for Scientific Research (CW-NWO) and by The Netherlands Foundation for Technical Sciences (STW). Support and sponsorship by COST Action D8/00097 (biocoordination chemistry) is kindly acknowledged. The authors thank JohnsonMatthey (Reading, UK) for their generous loan of K(2)PtCl(4)

Autor: Robillard, Valentijn, Meeuwenoord, van Der Marel GA, van Boom JH, Reedijk

Publikováno v: Angewandte Chemie (International ed. in English). 39(17)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1e4f2f329a3906776e5fa2c3e242926
https://pubmed.ncbi.nlm.nih.gov/11028044

Solid-Phase Synthesis of a Monofunctional trans-a(2)Pt(II) Complex Tethered to a Single-Stranded Oligonucleotide

Autor: Schmidt, Filippov, Meeuwenoord, van Der Marel GA, van Boom JH, Lippert, Reedijk

Publikováno v: Angewandte Chemie (International ed. in English). 39(2)

Cross-linking ability is possible with the oligonucleotide-tethered, monofunctional trans-Pt(II) complex shown. It was synthesized by a novel solid-phase approach comprising conjugation of immobilized tetrathymidylic acid with a trans-a(2)Pt(II) buil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7813ddd790ae5f18c6b77f5679be9ccd
https://pubmed.ncbi.nlm.nih.gov/10649415

Synthesis and biological evaluation of modified DNA fragments for the study of nucleotide excision repair in E. coli

Autor: van den Elst Ha, van der Marel Ga, van Boom Jh, van de Wetering Ki, Stuivenberg Hr, van der Kaaden Jc, Nico J. Meeuwenoord, Geri F. Moolenaar, R. Visse, Monaco, Nora Goosen, Esther E.A. Verhoeven

Publikováno v: Nucleosidesnucleotides. 18(6-7)

Three new cholesterol-containing phosphoramidites where synthesized and used in automated synthesis of modified DNA fragments. These cholesterol lesions are good substrates for the E. coli UvrABC endonuclease. In vitro they are incised from damaged D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863c78de11f6afd7edec7464d2606227
https://pubmed.ncbi.nlm.nih.gov/10474222