Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Van Boeckel CA"'
Publikováno v:
Organic Letters. 3:731-733
The cyclooctenol derivative 1 can be transformed into the nine-membered ring lactone 3, as well as the amino-containing carbocycles 4 and 5. The corresponding ketone 2 gives access to the conformationally locked azasugar 6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993786d42e121668966f9c5e851ebf3c
https://doi.org/10.1021/ol007047+
https://doi.org/10.1021/ol007047+
Autor:
Herbert Waldmann, Rob M. J. Liskamp, Elizabeth M. Nolan, Karl-Heinz Altmann, Horst Kessler, Harald Schwalbe, Gisbert Schneider, Bernhard Kräutler, van Boeckel Ca, Claudio Toniolo, François Diederich, Stephen J. Lippard, Buchner J, Sandra Schreiber, Bruno Samorì, Klaus Müller, Christopher T. Walsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcb8ddc5464f58417a5f46d0a279561
http://hdl.handle.net/11585/70469
http://hdl.handle.net/11585/70469
Publikováno v:
Nature structural biology. 2(9)
Computer modelling of the antithrombin III-heparin-thrombin complex inspired the synthesis of novel glycoconjugates, whose factor Xa and thrombin inhibitory activities can be adjusted in a rational way, leading to anticoagulants with unprecedented ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c89183aa208144082dfa15897bbdaf6
https://pubmed.ncbi.nlm.nih.gov/7552742
https://pubmed.ncbi.nlm.nih.gov/7552742
Autor:
Ghisaidoobe AT; Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University , Einsteinweg 55, 2300 RA Leiden, The Netherlands., van den Berg RJ, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AM, Koomen GJ, van Loevezijn A, Leemhuis M, Wennekes T, van der Stelt M, van der Marel GA, van Boeckel CA, Aerts JM, Overkleeft HS
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2014 Nov 13; Vol. 57 (21), pp. 9096-104. Date of Electronic Publication: 2014 Oct 17.
Autor:
Scheepstra M; Laboratory of Chemical Biology and Institute of Complex Molecular Systems (ICMS), Department of Biomedical Engineering, Technische Universiteit Eindhoven, Den Dolech 2, 5612 AZ Eindhoven (The Netherlands) http://www.tue.nl/cb., Nieto L, Hirsch AK, Fuchs S, Leysen S, Lam CV, in het Panhuis L, van Boeckel CA, Wienk H, Boelens R, Ottmann C, Milroy LG, Brunsveld L
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2014 Jun 16; Vol. 53 (25), pp. 6443-8. Date of Electronic Publication: 2014 May 12.
Autor:
van Lierop MJ; Department of Immune Therapeutics, MSD, Oss, The Netherlands. mariejose.vanlierop@merck.com, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, Plate R, Conti PG, Jans CG, Timmers CM, van Boeckel CA, Lusher SJ, McGuire R, van Schaik RC, de Vlieg J, Smeets RL, Hofstra CL, Boots AM, van Duin M, Ingelse BA, Schoonen WG, Grefhorst A, van Dijk TH, Kuipers F, Dokter WH
Publikováno v:
PloS one [PLoS One] 2012; Vol. 7 (11), pp. e48385. Date of Electronic Publication: 2012 Nov 12.
Autor:
Petitou M; Endotis Pharma, Parc Biocitech, 93230 Romainville, France. mauricepetitou@endotis.com, Nancy-Portebois V, Dubreucq G, Motte V, Meuleman D, de Kort M, van Boeckel CA, Vogel GM, Wisse JA
Publikováno v:
Thrombosis and haemostasis [Thromb Haemost] 2009 Nov; Vol. 102 (5), pp. 804-10.
Autor:
Altmann KH, Buchner J, Kessler H, Diederich F, Kräutler B, Lippard S, Liskamp R, Müller K, Nolan EM, Samori B, Schneider G, Schreiber SL, Schwalbe H, Toniolo C, van Boeckel CA, Waldmann H, Walsh CT
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2009 Jan 05; Vol. 10 (1), pp. 16-29.
Autor:
de Kort M; Department of Medicinal Chemistry, N.V. Organon, part of Schering-Plough Corporation, Molenstraat 110, PO Box 20, 5340 BH, Oss, The Netherlands. m.dekort@organon.com, Gianotten B, Wisse JA, Bos ES, Eppink MH, Mattaar E, Vogel GM, Dokter WH, Honing M, Vonsovic S, Smit MJ, Wijkmans JC, van Boeckel CA
Publikováno v:
ChemMedChem [ChemMedChem] 2008 Aug; Vol. 3 (8), pp. 1189-93.
Autor:
de Kort M; NV Organon, Molenstraat 110, 5340 BH, Oss, The Netherlands. m.dekort@organon.com, Buijsman RC, van Boeckel CA
Publikováno v:
Drug discovery today [Drug Discov Today] 2005 Jun 01; Vol. 10 (11), pp. 769-79.