Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Van B. T. Ta"'
Autor:
Hassan Jumaa, Marjolein J. W. de Bruijn, Martina P. Bach, Anne E. Corcoran, Hedda Wardemann, Markus Josef Zoller, Rudi W. Hendriks, Louise S. Matheson, Van B. T. Ta
Publikováno v:
Journal of Immunology, 189(10), 4842-4851. American Association of Immunologists
Mice deficient for the adapter protein Slp65 (also known as Blnk), a key component in precursor-BCR (pre-BCR) signaling, spontaneously develop pre-B cell leukemia. In these leukemias, proliferation is thought to be driven by constitutive Jak3/Stat5 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab4b552831d4b4bf1b880c6bd31b52a
https://doi.org/10.4049/jimmunol.1201440
https://doi.org/10.4049/jimmunol.1201440
Publikováno v:
Leukemia, 25(1), 48-56. Nature Publishing Group
The adapter protein Slp65 and Bruton's tyrosine kinase (Btk) are key components of the precursor-B (pre-B) cell receptor (pre-BCR) signaling pathway. Slp65-deficient mice spontaneously develop pre-B-cell leukemia, expressing high levels of the pre-BC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bcc6e34157c58eb23e7769690e776f
https://doi.org/10.1038/leu.2010.246
https://doi.org/10.1038/leu.2010.246
Autor:
Van B. T. Ta, Petra ter Brugge, Rudi W. Hendriks, Marjolein J. W. de Bruijn, Jan Piet van Hamburg, Pieter Fokko van Loo, Hans J. A. Diepstraten, Rogier Kersseboom
Publikováno v:
Blood, 115(7), 1385-1393. American Society of Hematology
The adapter protein Slp65 is a key component of the precursor-B (pre-B) cell receptor. Slp65-deficient mice spontaneously develop pre-B cell leukemia, but the mechanism by which Slp65(-/-) pre-B cells become malignant is unknown. Loss of Btk, a Tec-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d02d4b2a9ac91a0aae08c91544f5e95
https://doi.org/10.1182/blood-2009-05-222166
https://doi.org/10.1182/blood-2009-05-222166
Autor:
Dik C. van Gent, Petra ter Brugge, Rudi W. Hendriks, Guido Keijzers, Marjolein J. W. de Bruijn, Van B. T. Ta, Alex Maas
Publikováno v:
Blood, 114(1), 119-127. American Society of Hematology
The simian virus 40 (SV40) T antigen is a potent oncogene able to transform many cell types and has been implicated in leukemia and lymphoma. In this report, we have achieved sporadic SV40 T-antigen expression in mature B cells in mice, by insertion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969b17c96db31cd39cbc0de8390c6c97
https://doi.org/10.1182/blood-2009-01-198937
https://doi.org/10.1182/blood-2009-01-198937
Autor:
Rudolf W. Hendriks, Rogier Kersseboom, A. J. Esther Zijlstra, Hassan Jumaa, Pieter Fokko van Loo, Sabine Middendorp, Van B. T. Ta
Publikováno v:
The Journal of Immunology. 176:4543-4552
Bruton’s tyrosine kinase (Btk) and the adapter protein SLP-65 (Src homology 2 domain-containing leukocyte-specific phosphoprotein of 65 kDa) transmit precursor BCR (pre-BCR) signals that are essential for efficient developmental progression of larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674b75195fd333848a039ab8ea508204
https://doi.org/10.4049/jimmunol.176.8.4543
https://doi.org/10.4049/jimmunol.176.8.4543
Autor:
Stephan P. Persengiev, Jeroen Demmers, Timurs Maculins, Karel Bezstarosti, Karlyn Schellekens, Dik C. van Gent, Van B. T. Ta
Publikováno v:
Nature Precedings
The proapoptotic protein Bid is phosphorylated by ATM after double strand breaks (DSBs) induction and induces S-phase arrest by a mechanism that remains to be elucidated. Here we show that in mammalian cells, Bid is associated with Mre11, a subunit o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc80d76e9ecb92887f68c2255654531e
https://doi.org/10.1038/npre.2007.1203.1
https://doi.org/10.1038/npre.2007.1203.1