Computational Design of Phosphotriesterase Improves V-Agent Degradation Efficiency.

Autor: Kronenberg J; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Chu S; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Olsen A; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Britton D; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Halvorsen L; Center for Genomics and Systems Biology, New York University, New York, New York, United States.; Center for Computational Biology, Flatiron Institute, New York, New York, United States., Guo S; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Lakshmi A; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Chen J; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Kulapurathazhe MJ; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States., Baker CA; Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, United States., Wadsworth BC; Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, United States., Van Acker CJ; Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, United States., Lehman JG 3rd; Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, United States., Otto TC; Medical Toxicology Research Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, United States., Renfrew PD; Center for Genomics and Systems Biology, New York University, New York, New York, United States.; Center for Computational Biology, Flatiron Institute, New York, New York, United States., Bonneau R; Center for Genomics and Systems Biology, New York University, New York, New York, United States.; Center for Computational Biology, Flatiron Institute, New York, New York, United States., Montclare JK; Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States.; Department of Biomaterials, New York University College of Dentistry, New York, New York, United States.; Department of Radiology, New York University Grossman School of Medicine, New York, New York, United States.; Department of Biomedical Engineering, New York University Tandon School of Engineering, Brooklyn, New York, United States.; Department of Chemistry, New York University, New York, New York, United States.

Publikováno v: ChemistryOpen [ChemistryOpen] 2024 Jul; Vol. 13 (7), pp. e202300263. Date of Electronic Publication: 2024 Mar 01.