Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Vamsi Madgula"'
Publikováno v:
Materials Today Bio, Vol 27, Iss , Pp 101143- (2024)
Recent FDA modernization act 2.0 has led to increasing industrial R&D investment in advanced in vitro 3D models such as organoids, spheroids, organ-on-chips, 3D bioprinting, and in silico approaches. Liver-related advanced in vitro models remain the
Externí odkaz:
https://doaj.org/article/a0ff8d62dfba48a19f8146aed4b4801a
Autor:
Veeravalli, Vijayabhaskar, Cheruvu, Hanumanth Srikanth, Srivastava, Pratima, Vamsi Madgula, Lakshmi Mohan
Publikováno v:
In Journal of Pharmaceutical Analysis December 2020 10(6):522-531
Autor:
Vijayabhaskar Veeravalli, Hanumanth Srikanth Cheruvu, Pratima Srivastava, Lakshmi Mohan Vamsi Madgula
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 10, Iss 6, Pp 522-531 (2020)
Formulation/pharmaceutical excipients play a major role in formulating drug candidates, with the objectives of ease of administration, targeted delivery and complete availability. Many excipients used in pharmaceutical formulations are orphanized in
Externí odkaz:
https://doaj.org/article/f0c2518b6c714b90917195fe765b2980
Autor:
Anna Kerins, Marta Koszyczarek, Caroline Smith, Phil Butler, Rob Riley, Vamsi Madgula, Nilkanth Naik, Matthew R. Redinbo, Ian D. Wilson
Publikováno v:
Xenobiotica. 52:904-915
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bf51779b553a36ca19ef8799fbea4ea
https://doi.org/10.1080/00498254.2022.2128468
https://doi.org/10.1080/00498254.2022.2128468
Autor:
Anna, Kerins, Marta, Koszyczarek, Caroline, Smith, Phil, Butler, Rob, Riley, Vamsi, Madgula, Nilkanth, Naik, Matthew R, Redinbo, Ian D, Wilson
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 52(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77f4d8d7a12582bccd2eca5154cdf0f3
https://pubmed.ncbi.nlm.nih.gov/36149349
https://pubmed.ncbi.nlm.nih.gov/36149349
Autor:
Lakshmi Mohan Vamsi Madgula, Hanumanth Srikanth Cheruvu, Pratima Srivastava, Vijayabhaskar Veeravalli
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 10, Iss 6, Pp 522-531 (2020)
Journal of Pharmaceutical Analysis
Journal of Pharmaceutical Analysis
Formulation/pharmaceutical excipients play a major role in formulating drug candidates, with the objectives of ease of administration, targeted delivery and complete availability. Many excipients used in pharmaceutical formulations are orphanized in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e03216a35594022030016d2ca8a6652
https://doi.org/10.1016/j.jpha.2020.02.007
https://doi.org/10.1016/j.jpha.2020.02.007
Autor:
Jennifer A. Thomas, R. Jayachandra Babu, Lakshmi Mohan Vamsi Madgula, Vijayabhaskar Veeravalli, Ranjeet Prasad Dash, Nuggehally R. Srinivas
Publikováno v:
Drug Safety. 43:711-725
The introduction of novel, small-molecule Janus kinase inhibitors namely tofacitinib, baricitinib and upadacitinib has provided an alternative treatment option for patients with rheumatoid arthritis outside of traditional drugs and expensive biologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3ab2f425970d35b6b30439bac86f65
https://doi.org/10.1007/s40264-020-00938-z
https://doi.org/10.1007/s40264-020-00938-z
Autor:
Ashwinkumar V. Meru, Siddhartha De, Debnath Bhuniya, Nadim S. Shaikh, Kasim A. Mookhtiar, Kaushal Joshi, Rashmi Barbhaiya, Vamsi Madgula, Sandeep Bhosale, Amol A. Raje, Rajendra K. Kharul, Dhananjay Joshi, Amol Magdum, Fouzia Begum, Sonalee Athavankar, Hajare Atul Kashinath, Sandip Balwe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:238-243
Conceptual design and modification of urea moiety in chemotype PF-3845/04457845, the bench marking irreversible inhibitor of fatty acid amide hydrolase (FAAH), led to discovery of a novel nicotinamide-based lead 12a having reversible mechanism of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8afc28b56fce6740f7cbc39ee182d1
https://doi.org/10.1016/j.bmcl.2018.11.048
https://doi.org/10.1016/j.bmcl.2018.11.048
Autor:
Kasim A. Mookhtiar, Anita Chugh, Rahul D. Kaduskar, Siddhartha De, Dhananjay N. Umrani, Debnath Bhuniya, Keshav Naik, Santosh Kurhade, Prasad Shitole, Balasaheb Kobal, Pratima Patil, Amol A. Raje, Sandhya Chaturvedi Joshi, Vamsi Madgula, Vaibhav Jain, Satyanarayana Reddy, Vyavahare Vinod, Suhas Tambe, Venkata P. Palle, Jayasagar Gundu, Ganesh Bhat, Bhavesh Dave, Anil M. Deshpande, Sachin Kandalkar, Sujay Basu
Publikováno v:
European Journal of Medicinal Chemistry. 133:268-286
Glucokinase activators (GKAs) are among the emerging drug candidates for the treatment of type 2 diabetes (T2D). Despite effective blood glucose lowering in clinical trials, many pan-GKAs "acting both in pancreas and liver" have been discontinued fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc407021454742cbb5545882542a7f5
https://doi.org/10.1016/j.ejmech.2017.03.042
https://doi.org/10.1016/j.ejmech.2017.03.042
Autor:
Salunkhe Videsh, Madhu bala, Avinash Dhanave, Tanaji Mengawade, Vamsi Madgula, Mahesh Thakkar, Keshav Naik, Bheemashankar Kulkarni, Rahul D. Kaduskar, Dhananjay N. Umrani, Santosh Kurhade, Sachin Joshi, Amit Bhalerao, Sreekanth R. Rouduri, Vishal V Pathade, Rajkanth Petla, Swagatam Ray, Narayanan Hariharan, Kasim A. Mookhtiar, Satheesh Veerappa Avaragolla, Debnath Bhuniya, Jagadeesh Mavinahalli, Ashwini Tambe, Vaibhav Jain, Siddhartha De, Amol A. Raje, Ahmed Nadeem
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:1867-1873
In a pursuit to identify reversible and selective BTK inhibitors, two series based on 7H-pyrrolo[2,3-d]pyrimidine and 1H-pyrrolo[2,3-b]pyridine as the hinge binding core, have been identified. Structure activity relationship (SAR) exploration led to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59344b4bbaa9f604c182b2a0a030bcea
https://doi.org/10.1016/j.bmcl.2017.02.026
https://doi.org/10.1016/j.bmcl.2017.02.026