Zobrazeno 1 - 10
of 12 998
pro vyhledávání: '"Valproate"'
Publikováno v:
Medical Journal of Babylon, Vol 21, Iss 3, Pp 544-550 (2024)
Background:Autism spectrum disorder (ASD), a neurodevelopmental disease, is described by problems with social interaction and communication that arise at an early age. The only approved drugs for the treatment of ASD are risperidone and aripiprazole.
Externí odkaz:
https://doaj.org/article/0ae740063ecd42e893173bdf5e313ad1
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 34-42 (2024)
Relevance. The complexity of diagnosing and treating autism spectrum disorders (ASD) is attributed to their unknown etiology and pathophysiology. The investigation of ASD models induced by sodium valproate (VPA) holds significant importance in the de
Externí odkaz:
https://doaj.org/article/3fae37b694694ff38560e1d9c334c38a
Publikováno v:
Archives of Epilepsy, Vol 30, Iss 4, Pp 104-109 (2024)
Objective: Epilepsy affects over 1% of the global population. Polypodium vulgare L. has emerged in studies, suggesting its potential antiepileptic effect. This study evaluated the anticonvulsant efficacy of the hydroalcoholic extract of Polypodium vu
Externí odkaz:
https://doaj.org/article/ac28d2234d0244d7855b1b58e104a25b
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 83-86 (2024)
Status epilepticus (SE) is a life-threatening neurological condition with significant mortality. Rapid management is essential to minimize the mortality and disability of SE. Two recent trials provided evidence to guide SE management in early and est
Externí odkaz:
https://doaj.org/article/b378b63fc1674e1290de10258e9ce4d6
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 16, Iss 2, Pp 104-109 (2024)
Objective: to investigate the effects of sodium valproate on plasma concentrations of homocysteine, folate and vitamin B12 levels in epileptic patients with long-standing tonic-clonic seizures compared to newly diagnosed epileptic patients and health
Externí odkaz:
https://doaj.org/article/0c292e9ada2048d4b940c070e8befbd0
Autor:
Mohammad Hadi Zarei, Sami Akbulut, Maryam Zafari, Elham Saghaei, Zahra Lorigooini, Hossein Amini Khoei, Somaye Khosravi, Elham Bijad
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 7, Pp 298-306 (2024)
Objective: To explore the effect of black radish (Raphanus sativus L. var niger) root extract on liver enzymes, oxidative stress, and histopathological alterations in mice with sodium valproate-induced hepatotoxicity. Methods: Thirty-two mice were di
Externí odkaz:
https://doaj.org/article/571ec2faee9941d086d6b5795149f8e6
Autor:
Gök Duygu Kurt, Erdoğan Füsun Ferda, Göl Mehmet Fatih, Taheri Serpil, Önal Müge Gülcihan, Şükranlı Zeynep Yılmaz, Güvenilir Ecma, Yora Samed
Publikováno v:
The EuroBiotech Journal, Vol 8, Iss 3, Pp 103-114 (2024)
Valproic acid (VPA), is an antiepileptic drug and it has been known for a long time that exposure to VPA in the fetal period causes many behavioral, cognitive, and structural disorders. In this study, we aimed to evaluate the effects of the implement
Externí odkaz:
https://doaj.org/article/d0d962ee4cce407f8dc62f615a383ed5
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 2, Pp 132-154 (2024)
INTRODUCTION. Pharmacogenetic (PGx) testing plays a significant role in predicting the risk of adverse drug reactions (ADRs) associated with valproic acid (VPA) products, which are among the most prescribed medicinal products in neurology and psychia
Externí odkaz:
https://doaj.org/article/32c6ea0e49e5483e87a4e211daaad892
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
The P4HTM gene encodes a transmembrane prolyl 4-hydroxylase, which is responsible for the degradation of hypoxia-inducible transcription factors (HIF) under normoxia. Clinically, biallelic P4HTM variants have been identified in patients with hypotoni
Externí odkaz:
https://doaj.org/article/2e19d561a5c84cf5bc4fb184d691a5d7
Publikováno v:
Current Medicine Research and Practice, Vol 14, Iss 4, Pp 178-180 (2024)
Drug-induced vasculitis is essentially a small-vessel vasculitis. Histopathological changes in this condition are characterised by neutrophilic leucocytoclasia of the small vessels. To label it leucocytoclastic vasculitis, one must exclude other type
Externí odkaz:
https://doaj.org/article/e96b2d1f506644d6acff197a741bdc93