Activation of Xist by an evolutionarily conserved function of KDM5C demethylase.

Autor: Samanta MK; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Gayen S; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA.; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, Karnataka, 560012, India., Harris C; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Maclary E; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA.; Department of Biology, University of Utah, Salt Lake City, UT, 84112, USA., Murata-Nakamura Y; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Malcore RM; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Porter RS; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Garay PM; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA.; Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Vallianatos CN; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Samollow PB; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, 77843-4458, USA., Iwase S; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA.; Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA., Kalantry S; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, 48109-5618, USA. kalantry@umich.edu.

Publikováno v: Nature communications [Nat Commun] 2022 May 11; Vol. 13 (1), pp. 2602. Date of Electronic Publication: 2022 May 11.

Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation.

Autor: Vallianatos CN; Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Genetics and Genomics Graduate Program, University of Michigan, Ann Arbor, MI, 48109, USA., Raines B; Department of Psychology, University of Michigan, Ann Arbor, MI, 48109, USA., Porter RS; Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Genetics and Genomics Graduate Program, University of Michigan, Ann Arbor, MI, 48109, USA., Bonefas KM; Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; The University of Michigan Neuroscience Graduate Program, Ann Arbor, MI, USA., Wu MC; Neurodigitech, LLC, San Diego, CA, 92126, USA., Garay PM; Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; The University of Michigan Neuroscience Graduate Program, Ann Arbor, MI, USA., Collette KM; Department of Psychology, University of Michigan, Ann Arbor, MI, 48109, USA., Seo YA; Department of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Dou Y; Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA., Keegan CE; Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA., Tronson NC; Department of Psychology, University of Michigan, Ann Arbor, MI, 48109, USA. ntronson@umich.edu., Iwase S; Department of Human Genetics, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. siwase@umich.edu.

Publikováno v: Communications biology [Commun Biol] 2020 Jun 01; Vol. 3 (1), pp. 278. Date of Electronic Publication: 2020 Jun 01.

KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges.

Autor: Li, Chang-Yun^1,2 (AUTHOR), Wang, Wanhe³ (AUTHOR), Leung, Chung-Hang^4,5,6,7 (AUTHOR) duncanleung@um.edu.mo, Yang, Guan-Jun^1,2 (AUTHOR) champion2014@126.com, Chen, Jiong^1,2 (AUTHOR) chenjiong@nbu.edu.cn

Publikováno v: Molecular Cancer. 5/20/2024, Vol. 23 Issue 1, p1-23. 23p.

A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation.

Autor: Iwase S; Division of Newborn Medicine, Boston Children's Hospital and Department of Cell Biology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA; Department of Human Genetics, University of Michigan, 5815 Medical Science II, Ann Arbor, MI 48109, USA. Electronic address: siwase@umich.edu., Brookes E; Division of Newborn Medicine, Boston Children's Hospital and Department of Cell Biology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Agarwal S; Department of Human Genetics, University of Michigan, 5815 Medical Science II, Ann Arbor, MI 48109, USA., Badeaux AI; Division of Newborn Medicine, Boston Children's Hospital and Department of Cell Biology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Ito H; Department of Integrative Physiology and Neuroscience, Washington State University, 1815 Ferdinand's Lane, Pullman, WA 99164, USA., Vallianatos CN; Department of Human Genetics, University of Michigan, 5815 Medical Science II, Ann Arbor, MI 48109, USA., Tomassy GS; Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA., Kasza T; Department of Human Genetics, University of Michigan, 5815 Medical Science II, Ann Arbor, MI 48109, USA., Lin G; Molecular & Behavioral Neuroscience Institute and Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Thompson A; Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Gu L; Division of Newborn Medicine, Boston Children's Hospital and Department of Cell Biology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Kwan KY; Molecular & Behavioral Neuroscience Institute and Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Chen C; Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Sartor MA; Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Avenue, Ann Arbor, MI 48109, USA., Egan B; Active Motif Inc., Carlsbad, CA 92008, USA., Xu J; Department of Integrative Physiology and Neuroscience, Washington State University, 1815 Ferdinand's Lane, Pullman, WA 99164, USA. Electronic address: junxu@vetmed.wsu.edu., Shi Y; Division of Newborn Medicine, Boston Children's Hospital and Department of Cell Biology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: yshi@hms.harvard.edu.

Publikováno v: Cell reports [Cell Rep] 2016 Feb 09; Vol. 14 (5), pp. 1000-1009. Date of Electronic Publication: 2016 Jan 21.

Master regulators of neurogenesis: the dynamic roles of Ephrin receptors across diverse cellular niches.

Autor: Rasool, Dilan, Jahani-Asl, Arezu

Publikováno v: Translational Psychiatry; 11/6/2024, Vol. 14 Issue 1, p1-12, 12p