Zobrazeno 1 - 10
of 819
pro vyhledávání: '"Vallerie V, McLaughlin"'
Autor:
Richard Channick, Kelly M. Chin, Vallerie V. McLaughlin, Matthew R. Lammi, Roham T. Zamanian, Stefano Turricchia, Rose Ong, Lada Mitchell, Nick H. Kim
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 2, Pp 315-339 (2024)
Abstract Introduction Data on real-world clinical practice and outcomes of patients with pulmonary arterial hypertension associated with connective tissue disease (CTD-PAH) are scarce. The OPUS/OrPHeUS studies enrolled patients newly initiating macit
Externí odkaz:
https://doaj.org/article/c4b19ee288354c6089965ac76ad5d6fa
Autor:
Nick H. Kim, Kelly M. Chin, Vallerie V. McLaughlin, Hilary DuBrock, Ricardo Restrepo-Jaramillo, Zeenat Safdar, Gwen MacDonald, Nicolas Martin, Daniel Rosenberg, Maria Solonets, Richard Channick
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 1, Pp 85-107 (2024)
Abstract Introduction Portopulmonary hypertension (PoPH) carries a worse prognosis than other forms of pulmonary arterial hypertension (PAH). Data regarding use of PAH-specific therapies in patients with PoPH are sparse as they are usually excluded f
Externí odkaz:
https://doaj.org/article/d2d527f021da4bc98cd27bae7d4bdc4e
Autor:
Hunter Gillies, Murali M. Chakinala, Benjamin T. Dake, Jeremy P. Feldman, Marius M. Hoeper, Marc Humbert, Zhi‐Cheng Jing, Jonathan Langley, Vallerie V. McLaughlin, Ralph W. Niven, Stephan Rosenkranz, Xiaosha Zhang, Nicholas S. Hill
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract AV‐101 (imatinib) powder for inhalation, an investigational dry powder inhaled formulation of imatinib designed to target the underlying pathobiology of pulmonary arterial hypertension, was generally well tolerated in healthy adults in a p
Externí odkaz:
https://doaj.org/article/6cca6181d66a4a5aadc281acfa6b68ed
Autor:
Hunter Gillies, Ralph Niven, Benjamin T. Dake, Murali M. Chakinala, Jeremy P. Feldman, Nicholas S. Hill, Marius M. Hoeper, Marc Humbert, Vallerie V. McLaughlin, Martin Kankam
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Oral imatinib has been shown to be effective, but poorly tolerated, in patients with advanced pulmonary arterial hypertension (PAH). To maintain efficacy while improving tolerability, AV-101, a dry powder inhaled formulation of imatinib, w
Externí odkaz:
https://doaj.org/article/6e8ff00f40604cb1bb338a1660e59c87
Autor:
J. Gerry Coghlan, Sean Gaine, Richard Channick, Kelly M. Chin, Camille du Roure, J. Simon R. Gibbs, Marius M. Hoeper, Irene M. Lang, Stephen C. Mathai, Vallerie V. McLaughlin, Lada Mitchell, Gérald Simonneau, Olivier Sitbon, Victor F. Tapson, Nazzareno Galiè
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Further understanding of when to initiate therapies in pulmonary arterial hypertension (PAH) is important to improve long-term outcomes. Post hoc analyses of GRIPHON (NCT01106014) and exploratory analyses of TRITON (NCT02558231) suggested benefit of
Externí odkaz:
https://doaj.org/article/cf357fc51af24a7796e8e8637b6468a1
Autor:
Robert P. Frantz, Raymond L. Benza, Richard N. Channick, Kelly Chin, Luke S. Howard, Vallerie V. McLaughlin, Olivier Sitbon, Roham T. Zamanian, Anna R. Hemnes, Matt Cravets, Jean‐Marie Bruey, Robert Roscigno, David Mottola, Erin Elman, Lawrence S. Zisman, Hossein‐Ardeschir Ghofrani
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-7 (2021)
Aberrant kinase signaling that involves platelet‐derived growth factor receptor (PDGFR) α/β, colony stimulating factor 1 receptor (CSF1R), and stem cell factor receptor (c‐KIT) pathways may be responsible for vascular remodeling in pulmonary ar
Externí odkaz:
https://doaj.org/article/e7c6ee3ea34a41f89721a2c6c04b54de
Autor:
Vallerie V. McLaughlin, Richard Channick, Nick H. Kim, Robert P. Frantz, John W. McConnell, Lana Melendres‐Groves, Chad Miller, Ashwin Ravichandran, Josanna Rodriguez‐Lopez, Monika Brand, Sandrine Leroy, Graham Wetherill, Kelly M. Chin
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Macitentan is an oral endothelin receptor antagonist for the management of pulmonary arterial hypertension (PAH). The OPsumit® USers Registry (OPUS) and the OPsumit® Historical USers cohort (OrPHeUS) medical chart review provide real‐wor
Externí odkaz:
https://doaj.org/article/1ae0250ff48848e6abac30f59f11ea5e
Autor:
Vallerie V. McLaughlin, Richard N. Channick, Karimah S. Bell Lynum, Ronald J. Oudiz, Mona Selej, Victor F. Tapson, Lewis J. Rubin
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract The Pulmonary Arterial Hypertension‐Quality Enhancement Research Initiative Extension Program was designed to support physicians’ adherence to pulmonary arterial hypertension (PAH) guidelines. Guidelines were followed in >95% of patients
Externí odkaz:
https://doaj.org/article/b7b90230ad344a17965cb4c46642d4e1
Current status and barriers in pulmonary hypertension care delivery in India: A qualitative analysis
Autor:
Anand Reddy Maligireddy, Supriya Shore, A. Sreenivas Kumar, S. Harikrishnan, S. Ajit Mullasari, B. K. Sastry, Sameer Gupta, Nikhil Choudhary, Auras R. Atreya, Sonali Arora, Victor M. Moles, Vallerie V. Mclaughlin, Vikas Aggarwal
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 2, Pp n/a-n/a (2022)
Abstract Although pulmonary hypertension (PH) is widely prevalent in India, care delivery for this condition has unique challenges in a lower middle‐income country (LMIC). To describe care delivery for patients with PH and associated barriers in In
Externí odkaz:
https://doaj.org/article/d39a8c9f697849b7981068cfba06ec4e
Autor:
R. James White, Anton Vonk-Noordegraaf, Stephan Rosenkranz, Ronald J. Oudiz, Vallerie V. McLaughlin, Marius M. Hoeper, Ekkehard Grünig, Hossein-Ardeschir Ghofrani, Murali M. Chakinala, Joan A. Barberà, Christiana Blair, Jonathan Langley, Adaani E. Frost
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Initial combination therapy with ambrisentan and tadalafil reduced the risk of clinical failure events for treatment-naïve participants with pulmonary arterial hypertension (PAH) as compared to monotherapy. Previous studies in PA
Externí odkaz:
https://doaj.org/article/f44fd922b4584cd3b84761a83b713dd5