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Preventive and chronic mineralocorticoid receptor antagonism is highly beneficial in obese SHHF rats

Autor: Youcef, G, Olivier, A., Nicot, N., Müller, A., Deng, C, Labat, C, Fay, R, Rodriguez-Guéant, R-M, Leroy, C, Jaisser, F, Zannad, F, Lacolley, P., Vallar, L, Pizard, A

Publikováno v: British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2016, 173 (11), pp.1805-1819. ⟨10.1111/bph.13479⟩
British Journal of Pharmacology, 2016, 173 (11), pp.1805-1819. ⟨10.1111/bph.13479⟩

International audience; Background and purpose: Mineralocorticoid receptor (MR) activation contributes to heart failure (HF) progression. Its overactivity in obesity is thought to accelerate cardiac remodelling and HF development. Given that MR antag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffa11612d5f9e63dc169dff9fe205953
https://hal.univ-lorraine.fr/hal-01665069

Interplay of microRNAs, transcription factors and target genes: Linking dynamic expression changes to function

Autor: Nazarov, P. V. A, Reinsbach, Susanne, Muller, A. A, Nicot, N. A, Philippidou, Demetra, Vallar, L. A, Kreis, Stephanie

Publikováno v: Nucleic Acids Research, 41(5), 2817-2831. Oxford, United Kingdom: Oxford University Press (2013).

MicroRNAs (miRNAs) are ubiquitously expressed small non-coding RNAs that, in most cases, negatively regulate gene expression at the posttranscriptional level. miRNAs are involved in fine-tuning fundamental cellular processes such as proliferation, ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2658::0b9373877f021e21dd41b5d7102aa70a
http://orbilu.uni.lu/handle/10993/6355

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186 - “Melanomics”: analysis and integration of whole genomes, transcriptomes and miRNomes of primary melanoma patients

Autor: Reinsbach, S., Wienecke-Baldacchino, A., Ginolhac, A., Vallar, L., Muller, A., Krishna, A., Nazarov, P., May, P., Kreis, S.

Publikováno v: In European Journal of Cancer July 2016 61 Supplement 1:S32-S32