Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Validamine"'
1
C-5a-substituted validamine type glycosidase inhibitors
Autor: Roland Fischer, Michael Schalli, Stephen G. Withers, Christina Tysoe, Martin Thonhofer, Andrés G. Santana, Andreas Wolfsgruber, Arnold E. Stütz
Publikováno v: Carbohydrate Research. :1-9
A series of N-alkyl derivatives of the D-galactosidase inhibitor 1,4-di-epi-validamine featuring lipophilic substituents at position C-5a was prepared and screened for their glycosidase inhibitory properties. Products turned out selective for β-gala
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc0e5b2401c0da8fd29b7f7de47576a
https://doi.org/10.1016/j.carres.2017.01.006
Zobrazit plný text záznamu
2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
3
Design and Synthesis of 5a-Carbaglycopyranosylamime Glycosidase Inhibitors
Autor: Seiichiro Ogawa, Miki Kanto
Publikováno v: Current Topics in Medicinal Chemistry. 9:58-75
5a-Carba-alpha-D-glucopyranosylamine, validamine, and analogous compounds valienamine and valiolamine, have proved to be important lead compounds for development of clinically useful medicines, including the very strong alpha-glucosidase inhibitor, v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37f80830068f75221ca9cf916c9274d
https://doi.org/10.2174/156802609787354324
Zobrazit plný text záznamu
4
Synthesis and Biological Evaluation of α-L-Fucosidase Inhibitors: 5a-Carba-α-L-fucopyranosylamine and Related Compounds
Autor: Takashi Odagiri, Hironobu Hashimoto, Hideya Yuasa, Ayako Maruyama, Seiichiro Ogawa
Publikováno v: European Journal of Organic Chemistry. 2001:967-974
5a-Carba-α-L-fucopyranosylamine (5), an α-glucosidase inhibitor validamine analog possessing an α-L-fucose-type structure, and four related compounds (4 and 6−8) were synthesized and their glycosidase inhibitory potential determined. Carbafucosy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bc6febf9b6a49fc5924fc4cdae46009
https://doi.org/10.1002/1099-0690(200103)2001:5<967::aid-ejoc967>3.0.co
Zobrazit plný text záznamu
5
A novel and concise synthesis of (±) 2-epi-validamine
Autor: Kamyar Afarinkia, Farzana Mahmood
Publikováno v: Tetrahedron. 55:3129-3140
(±) 2-epi-Validamine has been synthesised in five steps by the chemical manipulation of the bicyclic lactone cycloadduct of ethyl coumalate and vinylene carbonate.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2ad863d0b3d833ceb3767b79d015104
https://doi.org/10.1016/s0040-4020(99)00071-x
Zobrazit plný text záznamu
7
Purification and characterization of β-glucosidase from Reticulitermes flaviceps and its inhibition by valienamine and validamine
Autor: Xue, Y, Jin, L, Liu, Z, Zhang, J, Zheng, Y
Publikováno v: African Journal of Biotechnology; Vol 7, No 24 (2008)
β-Glucosidase plays a very important role in the carbohydrate metabolism and it is the key enzyme that releases glucose for use as an energy and carbon source for termite. The β-glucosidase from the salivary glands of Reticulitermes flaviceps was p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=78975075580c::ffc2f01392a575205022bafaa0e10a1c
https://www.ajol.info/index.php/ajb/article/view/59644
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje