Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Valeska Lizzi Lagranha"'
Autor:
Valeska Lizzi Lagranha, Ursula Matte, Talita Giacomet de Carvalho, Bianca Seminotti, Carolina Coffi Pereira, David M Koeller, Michael Woontner, Stephen I Goodman, Diogo Onofre Gomes de Souza, Moacir Wajner
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90477 (2014)
We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as well as of the glutamate transporters GLAST and GLT1 in cerebral cortex and striatum of wild
Externí odkaz:
https://doaj.org/article/a9b5c58ab51645b29375a4783bc432de
Autor:
Matias Melendez, Valeska Lizzi Lagranha, André Baptista, Paulo Arlei Lompa, Roberto Giugliani, Ursula Matte
Publikováno v:
Clinical and Biomedical Research, Vol 31, Iss 4 (2012)
Background: tendons are part of the connective tissue that joins muscle to bone. Tendon injuries are a problem, since they have a poor ability to regenerate spontaneously. Alternative treatments involving the injection of local growth factors and gen
Externí odkaz:
https://doaj.org/article/f6881ddc4bd24e658f26919c2bc9bfd9
Autor:
Dirnete Diel, Roselena Silvestri Schuh, Fernanda Bruxel, Helder Ferreira Teixeira, Ursula da Silveira Matte, Valeska Lizzi Lagranha
Publikováno v:
European Journal of Pharmaceutical Sciences. 111:29-37
Mucopolysaccharidosis type I (MPS I) is an autosomal recessive disease caused by deficiency of α-l-iduronidase (IDUA), which results in the lysosomal accumulation of glycosaminoglycans (GAG) leading to widespread clinical manifestations. The microen
Autor:
Valeska Lizzi Lagranha, Giuseppe Ávila Testa, Talita Giacomet de Carvalho, Guilherme Baldo, Roberto Giugliani, Ursula da Silveira Matte, Bárbara Zambiasi Martinelli
Publikováno v:
Journal of materials science. Materials in medicine. 28(3)
Mucopolysaccharidosis type I (MPS I) is caused by a deficiency of α-L-iduronidase (IDUA), resulting in accumulation of glycosaminoglycans (GAG) in lysosomes. Microencapsulation of recombinant cells is a promising gene/cell therapy approach that coul
Autor:
Roberto Giugliani, Ursula da Silveira Matte, Talita Giacomet de Carvalho, Valeska Lizzi Lagranha
Publikováno v:
Journal of Microencapsulation. 30:383-389
Cell encapsulation, although a promising strategy to deliver therapeutic products, is hampered by immune response against biomaterials. The aim of this article is to assess the effect of prednisolone on enzyme release by microencapsulated cells impla
Autor:
Valeska Lizzi Lagranha, Ursula da Silveira Matte, Roberto Giugliani, Guilherme Baldo, Osvaldo Alfonso Pinto Artigalas, Ida Vanessa Doederlein Schwartz, Fabiana Quoos Mayer
Publikováno v:
ResearcherID
Mucopolysaccharidosis I (MPS I) is a genetic disorder caused by mutations on α-L-iduronidase (IDUA) gene, leading to low or null enzyme activity. As nonsense mutations are present in about two thirds of the patients, stop codon read through (SCRT) i
Autor:
Fabiana Quoos Mayer, Guilherme Baldo, Ursula da Silveira Matte, Roberto Giugliani, Valeska Lizzi Lagranha, Talita Giacomet de Carvalho
Publikováno v:
Artificial Organs. 34:434-439
Here, we show the effects of cryopreservation and hypothermic storage upon cell viability and enzyme release in alginate beads containing baby hamster kidney cells overexpressing alpha-L-iduronidase (IDUA), the enzyme deficient in mucopolysaccharidos
Autor:
César A. J. Ribeiro, Francine Hehn de Oliveira, Stephen I. Goodman, Michael Woontner, Carolina Coffi Pereira, Alexandre Umpierrez Amaral, Diogo de Souza, Bianca Seminotti, Moacir Wajner, Valeska Lizzi Lagranha, Cristiane Cecatto
Publikováno v:
Brain research. 1620
Bioenergetics dysfunction has been postulated as an important pathomechanism of brain damage in glutaric aciduria type I, but this is still under debate. We investigated activities of citric acid cycle (CAC) enzymes, lactate release, respiration and
Autor:
Diogo O. Souza, Ursula da Silveira Matte, Talita Giacomet de Carvalho, Bianca Seminotti, David M. Koeller, Valeska Lizzi Lagranha, Moacir Wajner, Carolina Coffi Pereira, Michael Woontner, Stephen I. Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90477 (2014)
PLoS ONE
PLoS ONE
We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as well as of the glutamate transporters GLAST and GLT1 in cerebral cortex and striatum of wild
Autor:
Paula Pierozan, Mateus Struecker da Rosa, Carolina Gonçalves Fernandes, Guilhian Leipnitz, Bianca Seminotti, Moacir Wajner, Valeska Lizzi Lagranha, Rafael Wolter Martell, Estela Natacha Brandt Busanello
Publikováno v:
Molecular genetics and metabolism. 109(2)
3-Hydroxy-3-methylglutaryl-CoA lyase (HL) deficiency is a genetic disorder biochemically characterized by predominant accumulation of 3-hydroxy-3-methylglutaric (HMG) and 3-methylglutaric (MGA) acids in tissues and biological fluids of affected indiv