Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Valeryi K, Lishko"'
Autor:
Nataly P. Podolnikova, Valeryi K. Lishko, Robert Roberson, Zhiqian Koh, Dmitry Derkach, David Richardson, Michael Sheller, Tatiana P. Ugarova
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
The complement receptor CR3, also known as integrin Mac-1 (CD11b/CD18), is one of the major phagocytic receptors on the surface of neutrophils and macrophages. We previously demonstrated that in its protein ligands, Mac-1 binds sequences enriched in
Externí odkaz:
https://doaj.org/article/7b763c6a9112460eb1efa32efabcdf8e
Leukocyte integrin Mac-1 (CD11b/CD18, αMβ2, CR3) acts as a functional receptor for platelet factor 4
Publikováno v:
Journal of Biological Chemistry. 293:6869-6882
Platelet factor 4 (PF4) is one of the most abundant cationic proteins secreted from α-granules of activated platelets. Based on its structure, PF4 was assigned to the CXC family of chemokines and has been shown to have numerous effects on myeloid le
Publikováno v:
Research and Reports in Biochemistry. 6:39-55
LL-37, a cationic antimicrobial peptide, has numerous immune-modulating effects. However, the identity of a receptor(s) mediating the responses in immune cells remains uncertain. We have recently demonstrated that LL-37 interacts with the αMI-domain
Autor:
Ramya Turaga, Tatiana P. Ugarova, Michael R. Sheller, Valeryi K. Lishko, Hadil Owaynat, Ivan S. Yermolenko
Publikováno v:
Thrombosis Research. 136:1231-1239
The initial accumulation of platelets after vessel injury is followed by thrombin-mediated generation of fibrin which is deposited around the plug. While numerous in vitro studies have shown that fibrin is highly adhesive for platelets, the surface o
Publikováno v:
The Journal of biological chemistry. 293(18)
Platelet factor 4 (PF4) is one of the most abundant cationic proteins secreted from α-granules of activated platelets. Based on its structure, PF4 was assigned to the CXC family of chemokines and has been shown to have numerous effects on myeloid le
Publikováno v:
Journal of Thrombosis and Haemostasis. 10:1081-1090
Summary. Background: Fibrinogen and plasminogen strongly reduce adhesion of leukocytes and platelets to fibrin clots, highlighting a possible role for these plasma proteins in surface-mediated control of thrombus growth and stability. In particular,
Autor:
Stanislav P. Oshkadyerov, Tatiana P. Ugarova, Ivan S. Yermolenko, Valeryi K. Lishko, Robert Ros, Alexander Fuhrmann, Sergei Magonov
Publikováno v:
Langmuir. 26:17269-17277
The deposition of a multilayered fibrinogen matrix on various surfaces results in a dramatic reduction of integrin-mediated cell adhesion and outside-in signaling in platelets and leukocytes. The conversion of a highly adhesive, low-density fibrinoge
Publikováno v:
The FASEB Journal. 29
Publikováno v:
The FASEB Journal. 29
Autor:
Andriy V. Podolnikov, Thomas A. Haas, Nataly P. Podolnikova, Tatiana P. Ugarova, Valeryi K. Lishko
Publikováno v:
Biochemistry. 54(6)
The broad recognition specificity exhibited by integrin α(M)β2 (Mac-1, CD11b/CD18) has allowed this adhesion receptor to play innumerable roles in leukocyte biology, yet we know little about how and why α(M)β2 binds its multiple ligands. Within