Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Valery Zayat"'
Autor:
Zuzanna Kuczynska, Pawan Kumar Neglur, Erkan Metin, Michal Liput, Marzena Zychowicz, Valery Zayat, Natalia E. Krześniak, Leonora Buzanska, Marta Kot
Publikováno v:
Folia Neuropathologica, Vol 62, Iss 1, Pp 32-46 (2024)
Human induced pluripotent stem cells (hiPSCs) are a potential source of somatic cells for cell therapies due to their ability to self-renew and differentiate into various cells of the body. To date, the clinical application of hiPSCs has been limited
Externí odkaz:
https://doaj.org/article/4753d037bcb6466b862fca68646726d5
Autor:
Moriyah Naama, Moran Rahamim, Valery Zayat, Shulamit Sebban, Ahmed Radwan, Dana Orzech, Rachel Lasry, Annael Ifrah, Mohammad Jaber, Ofra Sabag, Hazar Yassen, Areej Khatib, Silvina Epsztejn-Litman, Michal Novoselsky-Persky, Kirill Makedonski, Noy Deri, Debra Goldman-Wohl, Howard Cedar, Simcha Yagel, Rachel Eiges, Yosef Buganim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Human trophoblast stem cells (hTSCs) can be derived from embryonic stem cells (hESCs) or be induced from somatic cells by OCT4, SOX2, KLF4 and MYC (OSKM). Here we explore whether the hTSC state can be induced independently of pluripotency, a
Externí odkaz:
https://doaj.org/article/d0c4b6ee563d4a668d24fbf8c84f012e
Autor:
Valery Zayat, Zuzanna Kuczynska, Michal Liput, Erkan Metin, Sylwia Rzonca-Niewczas, Marta Smyk, Tomasz Mazurczak, Alicja Goszczanska-Ciuchta, Pawel Leszczynski, Dorota Hoffman-Zacharska, Leonora Buzanska
Publikováno v:
Cells, Vol 12, Iss 2, p 339 (2023)
Dravet syndrome (DRVT) is a rare form of neurodevelopmental disorder with a high risk of sudden unexpected death in epilepsy (SUDEP), caused mainly (>80% cases) by mutations in the SCN1A gene, coding the Nav1.1 protein (alfa-subunit of voltage-sensit
Externí odkaz:
https://doaj.org/article/fda844ebb4364affb5ff16e68a9a3231
Publikováno v:
Cells, Vol 11, Iss 19, p 3119 (2022)
Mutations in the SCN1A gene can cause a variety of phenotypes, ranging from mild forms, such as febrile seizures and generalized epilepsy with febrile seizures plus, to severe, such as Dravet and non-Dravet developmental epileptic encephalopathies. U
Externí odkaz:
https://doaj.org/article/388f5fb2e04b495896de5cfb8ff54bd6
Autor:
Shulamit Sebban, Debra Goldman-Wohl, Moriyah Naama, Hazar Yassen, Kirill Makedonski, Ofra Sabag, Noy Deri, Michal Novoselsky-Persky, Howard Cedar, Mohammad Jaber, Simcha Yagel, Ahmed Radwan, Rachel Eiges, Rachel Lasry, Moran Rahamim, Valery Zayat, Yosef Buganim, Dana Orzech, Silvina Epsztejn-Litman, Areej Khatib
SUMMARYRecent studies demonstrated that human trophoblast stem-like cells (hTS-like cells) can be derived from naïve embryonic stem cells or be induced from somatic cells by the pluripotency factors, OSKM. This raises two main questions; (i) whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7896abe4a56d473be9ab26f5c4ea885
https://doi.org/10.1101/2021.11.10.468044
https://doi.org/10.1101/2021.11.10.468044
Autor:
Michal Liput, Zuzanna Kuczynska, Chiara Magliaro, Leonora Buzanska, Arti Ahluwalia, Valery Zayat
Mitochondria are cellular organelles involved in generating energy to power various processes in the cell. Although the pivotal role of mitochondria in neurogenesis was demonstrated (first in animal models), very little is known about their role in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41583c031df2939d4548fc3870f89396
http://hdl.handle.net/11568/1115661
http://hdl.handle.net/11568/1115661
Autor:
Kirill Makedonski, Oren Ram, Mohammad Jaber, Tommy Kaplan, Rachel Lasry, Ahmed Radwan, Noam Maoz, Shulamit Sebban, Michal Inbar, Noa Renous, Zvi Zakheim, Hana Benchetrit, Yosef Buganim, Avital Pushett, Valery Zayat
Publikováno v:
Cell stem cell
Cell Stem Cell
Cell Stem Cell
Summary Following fertilization, totipotent cells undergo asymmetric cell divisions, resulting in three distinct cell types in the late pre-implantation blastocyst: epiblast (Epi), primitive endoderm (PrE), and trophectoderm (TE). Here, we aim to und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02997ea82f833db942221c96399a4d02
Autor:
Shulamit Sebban, Danielle Stave, Hana Benchetrit, Tao Wu, Shay Herman, Andrew Xiao, Niek van Wietmarschen, Peter M. Lansdorp, Kirill Makedonski, Rachel Lasry, Noam Maoz, Yosef Buganim, Nataly Yom Tov, Valery Zayat
Publikováno v:
Cell stem cell, 17(5), 543-556. CELL PRESS
Induced pluripotent stem cells (iPSCs) undergo extensive nuclear reprogramming and are generally indistinguishable from embryonic stem cells (ESCs) in their functional capacity and transcriptome and DNA methylation profiles. However, direct conversio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6190bcf1a8d6030cd74e74a2a758efa5
https://pubmed.ncbi.nlm.nih.gov/27487747
https://pubmed.ncbi.nlm.nih.gov/27487747
Autor:
Ewelina Macech, Mateusz Chmielarczyk, Anna Balcerak, Ryszard Konopiński, Alicja Trebinska, Jarosław Korczyński, Valery Zayat, Juliusz Wysocki, Magdalena Dziembowska, Elzbieta Sarnowska, Ewa A. Grzybowska
HAX-1, a multifunctional protein involved in the regulation of apoptosis, cell migration, and calcium homeostasis, binds the 3' untranslated region motifs of specific transcripts. This suggests that HAX-1 plays a role in post-transcriptional regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da4355ed6928165c2ecd8942dd80190
https://europepmc.org/articles/PMC4281894/
https://europepmc.org/articles/PMC4281894/
Autor:
Aleksandra, Habich, Ilona, Szablowska-Gadomska, Valery, Zayat, Leonora, Buzanska, Krystyna, Domańska-Janik
Publikováno v:
Acta neurobiologiae experimentalis. 73(1)
In the context of cell therapy, the epigenetic status of core stemness transcription factor (STF) genes regulating the cell proliferation/differentiation program is of primary interest. Our results confirmed that in vitro differentiation of the umbil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ea12adf499e3f49591ff413a191316f
https://pubmed.ncbi.nlm.nih.gov/23595290
https://pubmed.ncbi.nlm.nih.gov/23595290