Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Valery V. Fokin"'
Autor:
Katharina Grotsch, Valery V. Fokin
Publikováno v:
ACS Central Science, Vol 8, Iss 2, Pp 156-168 (2022)
Externí odkaz:
https://doaj.org/article/8262896fe2e9475fb8c6a8612ffa10ab
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Time-dependent monitoring of the reactive intermediates provides valuable information about the mechanism of a synthetic transformation. However, the process frequently involves intermediates with short lifetimes that significantly challenge the acce
Externí odkaz:
https://doaj.org/article/4d2bf95f89324f5c94e45ae8a58e9f81
Autor:
Tineke Lauwaet, Yukiko Miyamoto, Sozaburo Ihara, Christine Le, Jarosław Kalisiak, Keith A Korthals, Majid Ghassemian, Diane K Smith, K Barry Sharpless, Valery V Fokin, Lars Eckmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0008224 (2020)
Giardiasis and other protozoan infections are major worldwide causes of morbidity and mortality, yet development of new antimicrobial agents with improved efficacy and ability to override increasingly common drug resistance remains a major challenge.
Externí odkaz:
https://doaj.org/article/ed36932d78294388be2840c2e73d1b52
Publikováno v:
Nature Chemistry.
Autor:
Valery V. Fokin, Dmitry B. Eremin
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:203-206
Supercharging reagents assist protein ionization by producing higher charge states and increasing signal intensities, thus improving sensitivity. Described here is an approach to employ a dual-spray ionization source with DMSO as a supercharging reag
Autor:
Dmitry B. Eremin, Valery V. Fokin
Publikováno v:
Journal of the American Chemical Society. 143:18374-18379
Water profoundly affects many organic reactions by accelerating them or changing their selectivity. Performing reactions "on-water" offers an intriguing opportunity to influence chemical reactivity. A nebulizer plume is an efficient way of generating
Publikováno v:
Molecules, Vol 17, Iss 7, Pp 8312-8333 (2012)
Efforts to discover new drugs for Alzheimer’s disease emphasizing multiple targets was conducted seeking to inhibit amyloid oligomer formation and to prevent radical formation. The tryptoline and tryptamine cores of BACE1 inhibitors previously iden
Externí odkaz:
https://doaj.org/article/1b542e1945244622b9036df43c4542d1
Autor:
Katharina Grotsch, Valery V. Fokin
Publikováno v:
ACS central science. 8(2)
At the intersection of science and medicine, government policy, and pop culture, cannabis has prompted society since the beginning of recorded history. And yet, there is comparatively little replicable data on the plant, its constituents, and their c
Autor:
Sozaburo Ihara, Shubhangi Aggarwal, Kirkwood M. Land, Valery V. Fokin, Jonathan Ang, Liangfang Zhang, Dmitry B. Eremin, Lars Eckmann, Lisa A. Wrischnik, Jeff Joseph A. Celaje, Yukiko Miyamoto
Publikováno v:
Journal of medicinal chemistry, vol 64, iss 10
J Med Chem
J Med Chem
Trichomonas vaginalis causes the most common, nonviral sexually transmitted infection. Only metronidazole (Mz) and tinidazole are approved for treating trichomoniasis, yet resistance is a clinical problem. The gold(I) complex, auranofin, is active ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3929af05378c1c6286817e074a6616
https://escholarship.org/uc/item/99v254ct
https://escholarship.org/uc/item/99v254ct
Publikováno v:
Chemistry – A European Journal. 25:1906-1909
Aliphatic, aromatic, and heteroaromatic aldehydes were readily converted to corresponding nitriles in a one-pot reaction sequence with hydroxylamine and sulfuryl fluoride. The reaction proceeds at room temperature, does not require metal catalysts an