Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Valery P. Nikolin"'
Autor:
Daniil V. Gladkikh, Aleksandra V. Sen′kova, Ivan V. Chernikov, Tatyana O. Kabilova, Nelly A. Popova, Valery P. Nikolin, Elena V. Shmendel, Mikhail A. Maslov, Valentin V. Vlassov, Marina A. Zenkova, Elena L. Chernolovskaya
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1252 (2021)
In this study, we examined the in vivo toxicity of the liposomes F consisting of 1,26-bis(cholest-5-en-3-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride, lipid-helper 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine and folate lipoco
Externí odkaz:
https://doaj.org/article/df1d1da4a6b245aa93611c072a0d6e74
Autor:
Valery P. Nikolin, Nelly A. Popova, Olga A. Luzina, Nariman F. Salakhutdinov, Alexandra L. Zakharenko, V. I. Kaledin, Olga I. Lavrik
Publikováno v:
Clinical & Experimental Metastasis. 38:431-440
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a repair enzyme for 3'-end DNA lesions, predominantly stalled DNA-topoisomerase 1 (Top1) cleavage complexes. Tdp1 is a promising target for anticancer therapy based on DNA damage caused by Top1 poisoning. Ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66250fb3526f3b296277a5b65b3b4938
https://doi.org/10.1007/s10585-021-10113-y
https://doi.org/10.1007/s10585-021-10113-y
Autor:
Aleksandra V Sen Kova, Marina A. Zenkova, Daniil V. Gladkikh, Valentin V. Vlassov, Mikhail A. Maslov, Tatyana O. Kabilova, Elena V. Shmendel, Nelly A. Popova, Elena L. Chernolovskaya, Ivan V. Chernikov, Valery P. Nikolin
Publikováno v:
Pharmaceutics, Vol 13, Iss 1252, p 1252 (2021)
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics
Volume 13
Issue 8
In this study, we examined the in vivo toxicity of the liposomes F consisting of 1,26-bis(cholest-5-en-3-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride, lipid-helper 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine and folate lipoco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbf6cf5690c20428d8ff010cb74f6ad
https://www.mdpi.com/1999-4923/13/8/1252
https://www.mdpi.com/1999-4923/13/8/1252
Autor:
Sergey S. Bogachev, Margarita V. Romanenko, Ekaterina A. Potter, Valery P. Nikolin, Ya. R. Efremov, O. S. Taranov, L. E. Zavyalov, Alexandr A. Ostanin, S. V. Netyosov, E. V. Dolgova, Elena R. Chernykh, N. A. Popova, A. S. Proskurina
Publikováno v:
Problems in oncology. 65:904-919
The effectiveness of the new therapeutic approach aimed at the destruction of the cancer cell community was evaluated on the immortalized human glioblastoma cell line U87. Initially, the reference elements of a new strategy for eradication of tumor-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5800447e24012f601d927e1e2198c00
https://doi.org/10.37469/0507-3758-2019-65-6-904-919
https://doi.org/10.37469/0507-3758-2019-65-6-904-919
Autor:
A. V. Shurlygina, Nelly A. Popova, E. V. Mel’nikova, S. I. Ilnitskaya, Natalia N. Kudryavtseva, Irina L. Kovalenko, D. A. Smagin, Valery P. Nikolin, A.G. Galyamina, V. A. Trufakin
Publikováno v:
Neuroscience and Behavioral Physiology. 49:384-398
Clinical practice and experimental studies have shown that the states of elevated anxiety and depression are often accompanied by impairments to immunity. Investigations over many years have shown that chronic social stress induced by repeated experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b551c1aa8a3a6934fe4050df0725a097
https://doi.org/10.1007/s11055-019-00745-9
https://doi.org/10.1007/s11055-019-00745-9
Autor:
S. M. Balakhnin, G. M. Sysoeva, S. Mark, Nelly A. Popova, E. L. Lushnikova, Evgeny V. Tretyakov, Valery P. Nikolin, Gérard Audran, V. I. Kaledin, M. V. Edeeva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 164:49-53
Effect of alkoxyamines on normal and tumor cells was studied in vitro and in vivo. In vitro experiments showed that alkoxyamines produce a dose-dependent toxic effect on cells of human breast tumor MCF7 line. Transplantation of Krebs-2 ascites carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb1f4b07b93c6a21d2a4fcd1c2724fd
https://doi.org/10.1007/s10517-017-3924-6
https://doi.org/10.1007/s10517-017-3924-6
Autor:
Vladimir A. Rogachev, S. S. Bogachev, E. V. Dolgova, A. S. Proskurina, Ekaterina A. Potter, Ya. R. Efremov, Valery P. Nikolin, E. I. Vereschagin, Nelly A. Popova, S. I. Baiborodin, Alexandr A. Ostanin, Elena R. Chernykh, O. S. Taranov, A. M. Minkevich, N. A. Kolchanov
Publikováno v:
Vavilovskij Žurnal Genetiki i Selekcii, Vol 20, Iss 5, Pp 716-722 (2016)
Previously, we reported on the development of a therapeutic regimen allowing eradication of primary murine Krebs-2 ascites transplants. This protocol involved multiple injections of dsDNA preparations administered during the NER and HR phases of repa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7076c1bde9de55259efb728776adcc7
https://vavilov.elpub.ru/jour/article/view/820
https://vavilov.elpub.ru/jour/article/view/820
Autor:
A. S. Proskurina, O. S. Taranov, E. I. Vereschagin, Vladimir A. Rogachev, Ekaterina A. Potter, Ya. R. Efremov, Nelly A. Popova, O. M. Andrushkevich, A. M. Minkevich, S. S. Bogachev, E. V. Dolgova, Valery P. Nikolin, D. D. Petrova, T. D. Dubatolova, N. A. Kolchanov, Elena R. Chernykh, Alexandr A. Ostanin, S. I. Baiborodin
Publikováno v:
Vavilovskij Žurnal Genetiki i Selekcii, Vol 20, Iss 5, Pp 723-735 (2016)
Cumulative evidence obtained in this series of studies has guided the logic behind the development of a novel composite dsDNA-based preparation whose therapeutic application according to the specific regimen completely cures the mice engrafted with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b8430efbb200a69a48375c3bcc6f2d
https://doi.org/10.18699/vj16.162
https://doi.org/10.18699/vj16.162
Autor:
Nelly A. Popova, Olga D. Zakharova, Alexandra L. Zakharenko, Valery P. Nikolin, D. N. Sokolov, Konstantin P. Volcho, Ivanhoe K. H. Leung, Arina A Chepanova, V. I. Kaledin, Jinal Patel, N.F. Salakhutdinov, Euphemia Leung, Ayesha Zafar, Jóhannes Reynisson, Olga I. Lavrik, Olga A. Luzina
Publikováno v:
European journal of medicinal chemistry. 161
The druggability of the tyrosyl-DNA phosphodiesterase 1 (Tdp1) enzyme was investigated in conjunction with topoisomerase 1 inhibition. A novel class of thiazole, aminothiazole and hydrazonothiazole usnic acid derivatives was synthesized and evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc437edb13f1821a94cb614f174c029b
https://pubmed.ncbi.nlm.nih.gov/30396105
https://pubmed.ncbi.nlm.nih.gov/30396105
Publikováno v:
Bulletin of experimental biology and medicine. 163(5)
We studied radioprotective effects of a preparation based on yeast RNA and its influence on therapeutic efficiency of ionizing radiation against transplanted tumors. Parenteral administration of yeast RNA preparation to mice in a dose of 10 mg 1 h pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97ab22b566923867d18c2ca17f85b46
https://pubmed.ncbi.nlm.nih.gov/28948545
https://pubmed.ncbi.nlm.nih.gov/28948545