Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valery N. Novoseletsky"'
Autor:
Aleksandr V. Kudriavtsev, Anna V. Vakhrusheva, Valery N. Novoseletsky, Marine E. Bozdaganyan, Konstantin V. Shaitan, Mikhail P. Kirpichnikov, Olga S. Sokolova
Publikováno v:
Viruses, Vol 14, Iss 8, p 1603 (2022)
The evolution and the emergence of new mutations of viruses affect their transmissibility and/or pathogenicity features, depending on different evolutionary scenarios of virus adaptation to the host. A typical trade-off scenario of SARS-CoV-2 evoluti
Externí odkaz:
https://doaj.org/article/365a983c17654b3580e6bcb8fa2144f6
Autor:
Vladislav S. Rybchenko, Anna A. Panina, Teimur K. Aliev, Olga N. Solopova, Dmitry S. Balabashin, Valery N. Novoseletsky, Dmitry A. Dolgikh, Petr G. Sveshnikov, Mikhail P. Kirpichnikov
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1915 (2021)
The main aim of our work was to create a full-length bispecific antibody (BsAb) as a vehicle for the targeted delivery of interferon-beta (IFN-β) to ErbB2+ tumor cells in the form of non-covalent complex of BsAb and IFN-β. Such a construct is a Cro
Externí odkaz:
https://doaj.org/article/d7f2e6622f0f463cb0c401052e6ec978
Autor:
Aleksandr V. Kudriavtsev, Anna V. Vakhrusheva, Valery N. Novoseletsky, Grigoriy A. Armeev, Mikhail A. Lozhnikov, Alexey K. Shaitan, Georgy M. Kobelkov, Konstantin V. Shaitan
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S15-S15 (2019)
Background: X-ray free-electron lasers (XFELs) in structural biology field opened a new opportunity for studying the structural dynamics of biomolecules. Structural dynamics analysis of single protein molecules by XFEL is based on the "diffraction-be
Externí odkaz:
https://doaj.org/article/ce6d3e61dbcb4bdf8b623ac3fb24b1ca
Autor:
Grigory A. Armeev, Mikhail A. Lozhnikov, Valery N. Novoseletsky, Aleksandr V. Kudriavtsev, Alexey К. Shaytan, Georgy M. Kobelkov, Konstantin V. Shaitan
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S36-S36 (2019)
Background: Free electron lasers open up new exciting possibilities for protein structure studies. Extremely high brilliance allows obtaining diffractograms from microcrystals, single particles (such as viruses) and, theoretically, even protein molec
Externí odkaz:
https://doaj.org/article/e5899a0ec74e432495d35aae7e17a00a
Autor:
Mikhail A. Lozhnikov, Georgiy M. Kobelkov, Grigoriy A. Armeev, Aleksandr V. Kudriavtsev, Valery N. Novoseletsky, Alexey K. Shaytan, Konstantin V. Shaitan
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S38-S38 (2019)
Background: X-ray free electron lasers (XFEL) proved to be powerful instruments for solving the problem of structural analysis of biological objects and studying its functional structural dynamics. The combination of huge intensity and short flashing
Externí odkaz:
https://doaj.org/article/e5d5fae5dd924499b66cea993beb8094
Autor:
Oksana V. Nekrasova, Alexandra L. Primak, Anastasia A. Ignatova, Valery N. Novoseletsky, Olga V. Geras’kina, Ksenia S. Kudryashova, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Alexander S. Arseniev, Alexey V. Feofanov
Publikováno v:
Toxins, Vol 12, Iss 12, p 802 (2020)
Recently developed fluorescent protein-scorpion toxin chimeras (FP-Tx) show blocking activities for potassium voltage-gated channels of Kv1 family and retain almost fully pharmacological profiles of the parental peptide toxins (Kuzmenkov et al., Sci
Externí odkaz:
https://doaj.org/article/6c6e8f2d8c2143f7a9303d4be758b138
Autor:
Dmitry E. Nolde, Valery N. Novoseletsky, Roman G. Efremov, and Alexander S. Arseniev, Anton O. Chugunov
Publikováno v:
Journal of Chemical Information and Modeling. 47:1150-1162
Integral membrane proteins (MPs) are pharmaceutical targets of exceptional importance. Modern methods of three-dimensional protein structure determination often fail to supply the fast growing field of structure-based drug design with the requested M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1316295361f21628ad7f62ada2e70896
https://doi.org/10.1021/ci600516x
https://doi.org/10.1021/ci600516x
Autor:
Valery N. Novoseletsky, Dmitry E. Nolde, and Alexander S. Arseniev, Roman G. Efremov, Anton O. Chugunov
Publikováno v:
Journal of chemical information and modeling. 47(3)
We describe a set of tests designed to check the ability of the new "membrane score" method (see the first paper of this series) to assess the packing quality of transmembrane (TM) alpha-helical domains in proteins. The following issues were addresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f247f75f3fceb38a51858bfad45d69
https://pubmed.ncbi.nlm.nih.gov/17371006
https://pubmed.ncbi.nlm.nih.gov/17371006
Autor:
Anton O. Chugunov, Valery N. Novoseletsky, Dmitry E. Nolde, Alexander S. Arseniev, Roman G. Efremov
Publikováno v:
Journal of Chemical Information & Modeling; May2007, Vol. 47 Issue 3, p1163-1170, 8p
Autor:
Anton O. Chugunov, Valery N. Novoseletsky, Dmitry E. Nolde, Alexander S. Arseniev, Roman G. Efremov
Publikováno v:
Journal of Chemical Information & Modeling; May2007, Vol. 47 Issue 3, p1150-1162, 13p