Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Valery G, Makarov"'
Autor:
Vera M. Kosman, Natalya M. Faustova, Marina V. Karlina, Valery G. Makarov, Marina N. Makarova
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 1, Pp 23-31 (2022)
Introduction: The pharmacokinetics studies are some of the necessary parts of the drugs preclinical investigations. Pharmacokinetic properties of new peptide drug 1-deamino-arginine-vasotocin (dAVT) in the form of an injection solution for intravenou
Externí odkaz:
https://doaj.org/article/b0d42a0728ca44b3b3ff0bd7612cb30f
Autor:
Vera M. Kosman, Marina V. Karlina, Ksenia V. Tyutina, Valery G. Makarov, Marina N. Makarova, Sergey V. Morozov, Eugenia E. Gushchina, Natalia V. Zhuravskaya
Publikováno v:
Reviews on Clinical Pharmacology and Drug Therapy. 20:297-308
BACKGROUND: Phenosanic acid is a synthetic antioxidant, the active ingredient of the original domestic drug recommended for the treatment of epilepsy. To improve the effectiveness and safety of the use of phenosanoic acid, additional study of its pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc4fb06cefb31d580b329813107eaaf2
https://doi.org/10.17816/rcf203297-308
https://doi.org/10.17816/rcf203297-308
Autor:
Olga N. Obolenskaia, Evgeniya A. Gorodetskaya, Elena I. Kalenikova, Margarita A. Belousova, Mikhail V. Gulyaev, Valery G. Makarov, Yury A. Pirogov, Oleg S. Medvedev
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1240 (2020)
Oxidative stress plays a key role in the pathogenesis of ischemic stroke. Coenzyme Q10 has a multi-targeting effect and may protect the brain against ischemic damage. The aim of our study was to evaluate the neuroprotective potential of ubiquinol by
Externí odkaz:
https://doaj.org/article/ee20ffa3f1194362b306a5cdc4ba9747
Publikováno v:
Biopharmaceutics & Drug Disposition. 43:3-10
The pharmacokinetic profiling of active compounds is necessary for drug development and application. Approaches to a pharmacokinetic study based on biological markers are alternatives to traditional approaches based on chromatographic methods. The ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226e4cc5120142352ee83aad9ca5f887
https://doi.org/10.1002/bdd.2305
https://doi.org/10.1002/bdd.2305
Autor:
Olga N. Pozharitskaya, Alexander N. Shikov, Into Laakso, Tuulikki Seppänen-Laakso, Igor E. Makarenko, Natalya M. Faustova, Marina N. Makarova, Valery G. Makarov
Publikováno v:
Journal of Functional Foods, Vol 17, Iss , Pp 227-234 (2015)
The gonads of sea urchins have been consumed by humans since ancient times. However, relatively little information is available on their biological activity. In the present study, we have consecutively extracted gonads of green sea urchins Strongyloc
Externí odkaz:
https://doaj.org/article/fb609024821f499eb9161905551185f3
Autor:
E. I. Kalenikova, N. S. Shapavo, Medvedev Os, E. A. Gorodetskaya, Valery G. Makarov, O. N. Obolenskaya
Publikováno v:
Pharmaceutical Chemistry Journal. 55:633-637
Drugs containing coenzyme Q10 (CoQ10) in the oxidized (ubiquinone) or reduced forms (ubiquinol) are used to treat diseases associated with redox imbalance and are intended only for peroral administration. Parenteral solubilized forms of CoQ10 could f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbec79e55f7e1832f655cc9b595c6a54
https://doi.org/10.1007/s11094-021-02471-4
https://doi.org/10.1007/s11094-021-02471-4
Autor:
Alexander N. Shikov, Andrey N. Tsitsilin, Olga N. Pozharitskaya, Valery G. Makarov, Michael Heinrich
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Historically Russia can be regarded as a “herbophilious” society. For centuries the multinational population of Russia has used plants in daily diet and for self-medication. The specificity of dietary uptake of medicinal plants (especially those
Externí odkaz:
https://doaj.org/article/9c34df0e829147339629485f60276440
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 2, Pp 106-111 (2021)
Introduction. The study of pharmacokinetics of medicinal substances and evaluation of their pharmacokinetic parameters is a necessary stage of pharmaceutical development of original medicinal agents, allowing to choose the composition and dosage form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232bc8c306c8b928fe54eddff0aec277
https://www.pharmjournal.ru/jour/article/view/889
https://www.pharmjournal.ru/jour/article/view/889
Autor:
Alexander N. Shikov, Olga N. Pozharitskaya, Natalia M. Faustova, Vera M. Kosman, Valery G. Makarov, Ebrahim Razzazi-Fazeli, Johannes Novak
Publikováno v:
Marine Drugs, Vol 17, Iss 10, p 577 (2019)
A glycopeptide fraction (GPF) from internal organs of green sea urchins (Strongylocentrotus droebachiensis Müller, Strongylocentrotidae) has been reported to be an effective bronchitis treatment. In this study, we evaluated the pharmacokinetic and t
Externí odkaz:
https://doaj.org/article/5b778e455ca1423b820a470296a70178
Autor:
Olga N. Pozharitskaya, Alexander N. Shikov, Natalya M. Faustova, Ekaterina D. Obluchinskaya, Vera M. Kosman, Heikki Vuorela, Valery G. Makarov
Publikováno v:
Marine Drugs, Vol 16, Iss 4, p 132 (2018)
Fucus vesiculosus L., known as bladderwrack, belongs to the brown seaweeds, which are widely distributed throughout northern Russia, Atlantic shores of Europe, the Baltic Sea, Greenland, the Azores, the Canary Islands, and shores of the Pacific Ocean
Externí odkaz:
https://doaj.org/article/eaff93a032a6469da7a4b3f5927e2136