Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Valery Chavez"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 11, p e1011672 (2023)
[This corrects the article DOI: 10.1371/journal.pcbi.1010263.].
Externí odkaz:
https://doaj.org/article/4a36c53a4462432aa9e48c9c0f8801a8
AI-Assisted chemical probe discovery for the understudied Calcium-Calmodulin Dependent Kinase, PNCK.
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1010263 (2023)
PNCK, or CAMK1b, is an understudied kinase of the calcium-calmodulin dependent kinase family which recently has been identified as a marker of cancer progression and survival in several large-scale multi-omics studies. The biology of PNCK and its rel
Externí odkaz:
https://doaj.org/article/2a1a6a96be1a47aa87bc46d19c89dc43
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105621- (2022)
Summary: Renal cell carcinoma (RCC) is a fatal disease when advanced. While immunotherapy and tyrosine kinase inhibitor-based combinations are associated with improved survival, the majority of patients eventually succumb to the disease. Through a co
Externí odkaz:
https://doaj.org/article/b8b3798421ac4f39a905bab97dd4dcaf
Autor:
Devon Lundine, George K. Annor, Valery Chavez, Styliana Maimos, Zafar Syed, Shuhong Jiang, Viola Ellison, Jill Bargonetti
Publikováno v:
Mol Cancer Res
The TP53 gene is mutated in 80% of triple-negative breast cancers. Cells that harbor the hot-spot p53 gene mutation R273H produce an oncogenic mutant p53 (mtp53) that enhances cell proliferative and metastatic properties. The enhanced activities of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899f6d1a9715cea48a6de6c587fabeba
https://doi.org/10.1158/1541-7786.mcr-22-0133
https://doi.org/10.1158/1541-7786.mcr-22-0133
Autor:
Jaime R. Merchan, Xi Chen, Alexey Pronin, Doraya El-Ashry, Nicolas Acquavella, Yuguang Ban, Valery Chavez, Yuqi Jing
Differential expression for mouse associated genes at day 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b56ea130adfc46c3e851686d85974f9
https://doi.org/10.1158/1541-7786.22516063
https://doi.org/10.1158/1541-7786.22516063
Autor:
Jill Bargonetti, Viola Ellison, Shuhong Jiang, Zafar Syed, Styliana Maimos, Valery Chavez, George K. Annor, Devon Lundine
Supplementary Figure from The C-terminus of Gain-of-Function Mutant p53 R273H Is Required for Association with PARP1 and Poly-ADP-Ribose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00027a90e631b7daaf20b6c199ddbf1b
https://doi.org/10.1158/1541-7786.22527540
https://doi.org/10.1158/1541-7786.22527540
Autor:
Jaime R. Merchan, Xi Chen, Alexey Pronin, Doraya El-Ashry, Nicolas Acquavella, Yuguang Ban, Valery Chavez, Yuqi Jing
The tumor microenvironment (TME) is a relevant target for novel biological therapies. MV-m-uPA and MV-h-uPA are fully retargeted, species-specific, oncolytic measles viruses (MV) directed against murine or human urokinase receptor (PLAUR/uPAR), expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::497e69dbbe51928d8619aacd739cfd9f
https://doi.org/10.1158/1541-7786.c.6541264
https://doi.org/10.1158/1541-7786.c.6541264
Autor:
Jaime R. Merchan, Xi Chen, Alexey Pronin, Doraya El-Ashry, Nicolas Acquavella, Yuguang Ban, Valery Chavez, Yuqi Jing
CBC and Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976275508acaa328e52b8530e3398b31
https://doi.org/10.1158/1541-7786.22516057
https://doi.org/10.1158/1541-7786.22516057
Autor:
Jaime R. Merchan, Xi Chen, Alexey Pronin, Doraya El-Ashry, Nicolas Acquavella, Yuguang Ban, Valery Chavez, Yuqi Jing
In situ hybridization for mouse uPAR and MV-N RNA (RNAscope).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a86734ee58c2484d63807f497f0dc1
https://doi.org/10.1158/1541-7786.22516060
https://doi.org/10.1158/1541-7786.22516060
Autor:
Jaime R. Merchan, Xi Chen, Alexey Pronin, Doraya El-Ashry, Nicolas Acquavella, Yuguang Ban, Valery Chavez, Yuqi Jing
Differential expression for mouse associated genes at day 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c191d424c165762319754478f86c290e
https://doi.org/10.1158/1541-7786.22516066.v1
https://doi.org/10.1158/1541-7786.22516066.v1