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pro vyhledávání: '"Valery Alakhov"'
ICAM-1 isoforms: specific activity and sensitivity to cleavage by leukocyte elastase and cathepsin G
Autor:
Philip D. King, Anne Papaioannou, Yves St-Pierre, Edouard F. Potworowski, Benoit Ochietti, Doris Legault, Claire Beauchemin, André M. Cantin, Olivier Robledo, Valery Alakhov, Claude Daniel
Publikováno v:
European Journal of Immunology. 33:1351-1360
The extracellular moiety of ICAM-1 consists of five Ig-like domains, the first and third domains mediating adhesion to integrin ligands. The ICAM-1 gene, however, gives rise to the expression of five alternative splice variants containing two, three,
Autor:
Pierre-Olivier Estève, Isabelle Lussier, Viatcheslav Medvedkine, Rosemonde Mandeville, Valery Alakhov, Mikhail Popkov
Publikováno v:
European Journal of Biochemistry. 251:155-163
A phage display library of random decapeptides was used to generate peptide ligands that can bind multidrug-resistance (MDR) drugs mimicking, in this respect, the drug-binding activity of P-glycoprotein. Seven peptide sequences were identified that s
Publikováno v:
Advances in genetics. 53
Amphiphilic block copolymers of poly(ethylene oxide) and poly(propylene oxide) called Pluronic or poloxamer are commercially available pharmaceutical excipients. They recently attracted considerable attention in gene delivery applications. First, the
Publikováno v:
Biochemical and biophysical research communications. 309(3)
The ICAM-1 adhesion molecule is expressed selectively at low levels on endothelial cells but is strongly upregulated in dysfunctional endothelial cells associated with inflammation, cancer, and atherogenesis. Using COS-7 cells transfected with murine
Autor:
Valery Alakhov, Grzegorz Pietrzynski, Kishore Patel, Alexander Kabanov, Lev Bromberg, T. Alan Hatton
Publikováno v:
Journal of Pharmacy & Pharmacology; Oct2004, Vol. 56 Issue 10, p1233-1241, 9p
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