Výsledky vyhledávání - "Valeriya O. Babich"

Akademický článek

Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential

Autor: Andrey V. Markov, Valeriya O. Babich, Irina I. Popadyuk, Oksana V. Salomatina, Evgeniya B. Logashenko, Nariman F. Salakhutdinov, Marina A. Zenkova

Publikováno v: Molecules, Vol 24, Iss 14, p 2644 (2019)

A series of novel deoxycholic acid (DCA) derivatives containing aliphatic diamine and aminoalcohol or morpholine moieties at the C3 position were synthesized by 3,26-epoxide ring-opening reactions. These compounds were investigated for their cytotoxi

Externí odkaz: https://doaj.org/article/8ed0411a3dcb4f9a9191830cbe0bd61c

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Dual Effect of Soloxolone Methyl on LPS-Induced Inflammation In Vitro and In Vivo

Autor: Marina A. Zenkova, Evgeniya B. Logashenko, Kirill V Odarenko, Vadim A Talyshev, Valeriya O. Babich, Oksana V. Salomatina, Nariman F. Salakhutdinov, Andrey V. Markov, Aleksandra V Sen'kova

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 7876, p 7876 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21

Plant-extracted triterpenoids belong to a class of bioactive compounds with pleotropic functions, including antioxidant, anti-cancer, and anti-inflammatory effects. In this work, we investigated the anti-inflammatory and anti-oxidative activities of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e379e7ef446f7c49800ee4c76aa35f92
https://www.mdpi.com/1422-0067/21/21/7876

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Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position

Autor: Oksana V. Salomatina, Evgeniya B. Logashenko, Marina A. Zenkova, Andrey V. Markov, Tatyana G. Tolstikova, Ekaterina A. Morozova, Nariman F. Salakhutdinov, Irina I. Popadyuk, Valeriya O. Babich

Publikováno v: Steroids. 127:1-12

Novel deoxycholic acid (DCA) derivatives were stereoselectively synthesised with –OH and –CH2SR moieties at the C-3 position, where R was a substituted aryl [2-aminophenyl (8) or 4-chlorophenyl (9)] or hetaryl [1-methylimidazolyl (5), 1,2,4-triaz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6518b715e1a881cfa755178599d87505
https://doi.org/10.1016/j.steroids.2017.08.016

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Autor: Evgeniya B. Logashenko, Nariman F. Salakhutdinov, Marina A. Zenkova, Valeriya O. Babich, Irina I. Popadyuk, Oksana V. Salomatina, Andrey V. Markov

Publikováno v: Molecules
Volume 24
Issue 14
Molecules, Vol 24, Iss 14, p 2644 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a7992c8a5f596f77de0380a5c7993d

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Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activity

Autor: Irina I. Popadyuk, Evgeniya B. Logashenko, Andrey V. Markov, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Valeriya O. Babich

Publikováno v: Bioorganicmedicinal chemistry letters. 27(16)

A new library of deoxycholic acid derivatives bearing nitrogen-containing moieties at the C-3 position was synthesised from epoxy derivative 1 via an epoxide ring-opening reaction promoted by aliphatic or cyclic diamines and fully characterised by NM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ccbf9ff698336beee8d168a64836b9
https://pubmed.ncbi.nlm.nih.gov/28688958

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