Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Valeriy V, Lyzogubov"'
Autor:
Gareth J. Morgan, Naveen Yarlagadda, Meera Mohan, Shayu Deshpande, Pingping Qu, Carolina Schinke, Maliha Khan, Katie R. Ryan, Bart Barlogie, Yan Wang, Antje Hoering, Eileen M Boyle, Maurizio Zangari, Brian A Walker, Sharmilan Thanendrarajan, Faith E. Davies, Cody Ashby, Samrat Roy Choudhury, Frits van Rhee, Christopher P. Wardell, Valeriy V. Lyzogubov
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 6, Pp 1-9 (2020)
Blood Cancer Journal
Blood Cancer Journal
Primary plasma cell leukemia (pPCL) is a rare and aggressive form of multiple myeloma (MM) that is characterized by the presence of ≥20% circulating plasma cells. Overall survival remains poor despite advances of anti-MM therapy. The disease biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62419d8b19e8a4818d41b69534a817d2
http://link.springer.com/article/10.1038/s41408-020-0336-z
http://link.springer.com/article/10.1038/s41408-020-0336-z
Autor:
Brian S. White, Mehmet Kemal Samur, Alexander V. Ratushny, Michael Mason, Gareth J. Morgan, Justin Guinney, Yi Cui, Pieter Sonneveld, Bailiang Li, Carolina Schinke, Fadi Towfic, Samuel A. Danziger, Hervé Avet-Loiseau, Matthew Trotter, Elias Chaibub Neto, Hongyue Y Dai, Valeriy V. Lyzogubov, Christine Eng, Jonathan Göke, Anjan Thakurta, Hongjie Chen, Andrew Dervan, William S. Dalton, Daniel Auclair, Douglas Bassett, Nikhil C. Munshi, Kenneth H. Shain, Fred K. Gruber, Boris Hayete, Brian A Walker, Aditya Pratapa, Frank Schmitz, Hartmut Goldschmidt, Thomas Yu, Dirk Hose, Erin Flynt, Kamlesh Bisht, Maria Ortiz, Yuanfang Guan, Konstantinos Mavrommatis, Dan Rozelle
Publikováno v:
Leukemia 34, 1866–1874 (2020)
Leukemia
Leukemia
While the past decade has seen meaningful improvements in clinical outcomes for multiple myeloma patients, a subset of patients do not benefit from current therapeutics for unclear reasons. Many gene expression-based models of risk have been develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95c98ba8ff90bd994e2b93c3b359762
https://doi.org/10.1038/s41375-020-0742-z
https://doi.org/10.1038/s41375-020-0742-z
Publikováno v:
Biochemical and biophysical research communications. 530(2)
Choroidal neovascularization (CNV) is the hallmark of wet age-related macular degeneration (AMD), a leading cause of irreversible blindness in the modern world. The objective for this study was to investigate the therapeutic potential of known antian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf9fe1d528f048a8ee430ec8caa5ccc
https://pubmed.ncbi.nlm.nih.gov/32800337
https://pubmed.ncbi.nlm.nih.gov/32800337
Autor:
Sami H. Uwaydat, Sunali Goyal, Omair Ali, Valeriy V. Lyzogubov, Puran S. Bora, Nalini S. Bora
Publikováno v:
Clinical & Experimental Ophthalmology. 44:610-617
Background To characterize the effect of aspirin (ASA) in mouse models of choroidal neovascularization (CNV) and retinal degeneration. Methods In vivo: Male C57BL/6 mice were given ASA in food or regular rodent diet. CNV was induced by argon laser ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a317c094d47ad993de541c2bba1f01
https://doi.org/10.1111/ceo.12721
https://doi.org/10.1111/ceo.12721
Publikováno v:
Experimental Eye Research. 127:143-152
Age-related macular degeneration (AMD) is a leading cause of irreversible blindness. This study was done to characterize dry AMD-like changes in mouse retinal pigment epithelium (RPE) and retina after polyethylene glycol (PEG) treatment. We injected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa022cc73ed3cc840cd01939aec7916
https://doi.org/10.1016/j.exer.2014.07.021
https://doi.org/10.1016/j.exer.2014.07.021
Autor:
Brian A Walker, Sharmilan Thanendrarajan, Veronica MacLeod, Frits van Rhee, Pingping Qu, Valeriy V. Lyzogubov, Eileen M Boyle, Shmuel Yaccoby, Wen Ling, Bart Barlogie, Carolina Schinke, Randal S Shelton, Maurizio Zangari
Publikováno v:
Blood. 134:508-508
Introduction - Multiple Myeloma (MM) is a hematologic malignancy characterized by clonal growth of differentiated plasma cells (PCs). Despite improvement in MM therapy, the disease remains mostly incurable and is characterized by recurrent relapses w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a5977ff99c3b5a9a1c5cc02c5c0116c
https://doi.org/10.1182/blood-2019-130595
https://doi.org/10.1182/blood-2019-130595
Autor:
Ruslana Tytarenko, Nalini S. Bora, Ammar Safar, Valeriy V. Lyzogubov, Puran S. Bora, Stephen J Davis
Publikováno v:
Retina. 32:1171-1180
Purpose The purpose of this article is to evaluate the effect of nicotine on anti-vascular endothelial growth factor therapy in the treatment of neovascular age-related macular degeneration. Methods One group of mice received nicotine in drinking wat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435b988832d8c58491b84c21570e4275
https://doi.org/10.1097/iae.0b013e31823496b8
https://doi.org/10.1097/iae.0b013e31823496b8
Publikováno v:
Current Immunology Reviews. 7:360-367
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d81f9e7d03bbe0424b05f6285ca7d96e
https://doi.org/10.2174/157339511796196656
https://doi.org/10.2174/157339511796196656
Autor:
Nalini S. Bora, Purushottam Jha, Ruslana Tytarenko, Juan Liu, Valeriy V. Lyzogubov, Puran S. Bora
Publikováno v:
Journal of Biological Chemistry. 286:20991-21001
The present study investigated the interactions among the complement membrane attack complex (MAC), CCL2, and VEGF that occur in vivo during the development of choroidal neovascularization (CNV). We first investigated the sequential expression of MAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acb884b11c945812cad036e7012c43f
https://doi.org/10.1074/jbc.m111.226266
https://doi.org/10.1074/jbc.m111.226266
Autor:
Brian A Walker, Gareth J. Morgan, Adam Rosenthal, Faith E. Davies, Cody Ashby, Valeriy V. Lyzogubov, Pingping Qu, Antje Hoering
Publikováno v:
Blood. 132:3897-3897
Introduction: Poor prognosis and drug resistance in multiple myeloma (MM) is associated with increased mutational load. APOBEC3B is a major contributor to mutagenesis, especially in myeloma patients with t(14;16) MAF subgroup. It was shown recently t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b44c06f2a04d019fada8c348fc8eec7
https://doi.org/10.1182/blood-2018-99-117067
https://doi.org/10.1182/blood-2018-99-117067