Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Valeriy P. Nikolin"'
Autor:
Tatyana E. Kornienko, Arina A. Chepanova, Alexandra L. Zakharenko, Aleksandr S. Filimonov, Olga A. Luzina, Nadezhda S. Dyrkheeva, Valeriy P. Nikolin, Nelly A. Popova, Nariman F. Salakhutdinov, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1210 (2024)
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is an important DNA repair enzyme and one of the causes of tumor resistance to topoisomerase 1 inhibitors such as topotecan. Inhibitors of this Tdp1 in combination with topotecan may improve the effectiveness of
Externí odkaz:
https://doaj.org/article/0d520dedd8ff4561923041ccb75fccda
Autor:
Genrikh S. Ritter, Anastasia S. Proskurina, Maria I. Meschaninova, Ekaterina A. Potter, Daria D. Petrova, Vera S. Ruzanova, Evgeniya V. Dolgova, Svetlana S. Kirikovich, Evgeniy V. Levites, Yaroslav R. Efremov, Valeriy P. Nikolin, Nelly A. Popova, Aliya G. Venyaminova, Oleg S. Taranov, Alexandr A. Ostanin, Elena R. Chernykh, Nikolay A. Kolchanov, Sergey S. Bogachev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4858 (2023)
It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective and radiotherapeutic effects. The experiments conducted in this study directly demonstrated that dsRNA was delivered into the cell in its native form and that
Externí odkaz:
https://doaj.org/article/e70b5d1a222f4c68a60325467cc5aca6
Autor:
Irina A. Chernyshova, Aleksandra L. Zakharenko, Nikolay N. Kurochkin, Nadezhda S. Dyrkheeva, Tatyana E. Kornienko, Nelly A. Popova, Valeriy P. Nikolin, Ekaterina S. Ilina, Timofey D. Zharkov, Maxim S. Kupryushkin, Vladimir E. Oslovsky, Mikhail S. Drenichev, Olga I. Lavrik
Publikováno v:
Molecules, Vol 28, Iss 1, p 323 (2022)
The use of cancer chemotherapy sensitizers is a promising approach to induce the effect of clinically used anticancer treatments. One of the interesting targets is Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), a DNA-repair enzyme, that may prevent the acti
Externí odkaz:
https://doaj.org/article/1bed77c2f7a94878b8b6b1122def7fc2
Autor:
Tatyana M. Khomenko, Alexandra L. Zakharenko, Arina A. Chepanova, Ekaterina S. Ilina, Olga D. Zakharova, Vasily I. Kaledin, Valeriy P. Nikolin, Nelly A. Popova, Dina V. Korchagina, Jóhannes Reynisson, Raina Chand, Daniel M. Ayine-Tora, Jinal Patel, Ivanhoe K. H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 126 (2019)
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is an important DNA repair enzyme in humans, and a current and promising inhibition target for the development of new chemosensitizing agents due to its ability to remove DNA damage caused by topoisomerase 1 (To
Externí odkaz:
https://doaj.org/article/552204bcfc0b4bb9b4e1a5b3189aa845
Autor:
Elena A. Khatuntseva, Vladimir M. Men’shov, Alexander S. Shashkov, Yury E. Tsvetkov, Rodion N. Stepanenko, Raymonda Ya. Vlasenko, Elvira E. Shults, Genrikh A. Tolstikov, Tatjana G. Tolstikova, Dimitri S. Baev, Vasiliy A. Kaledin, Nelli A. Popova, Valeriy P. Nikolin, Pavel P. Laktionov, Anna V. Cherepanova, Tatiana V. Kulakovskaya, Ekaterina V. Kulakovskaya, Nikolay E. Nifantiev
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 763-775 (2012)
Two new triterpenoid saponins 1 and 2 were isolated from the methanol extract of the roots of Acanthophyllum gypsophiloides Regel. These saponins have quillaic acid or gypsogenin moieties as an aglycon, and both bear similar sets of two oligosacchari
Externí odkaz:
https://doaj.org/article/f1def3b89a094092865bf971756cd8e7
Autor:
Alexandr A. Ostanin, Valeriy P. Nikolin, Vasiliy A Naprimerov, E. A. Burakova, Genrikh S. Ritter, Yaroslav R. Efremov, Anastasia S. Proskurina, Vera S. Ruzanova, Dmitry A. Stetsenko, Nelly A. Popova, Sergey A. Lashin, Zakhar S. Mustafin, Evgeniy V. Levites, Sergey S. Bogachev, Evgenia V. Dolgova, Elena R. Chernykh, Ekaterina A. Potter, S. S. Kirikovich
Publikováno v:
Anticancer Research. 41:3371-3387
Background/aim We compared the therapeutic efficacy of two recently developed experimental anticancer technologies: 1) in situ vaccination based on local immunotherapy with CpG oligonucleotides and anti-OX40 antibodies to activate antitumor immune re
Autor:
Tatyana O Kabilova, Aleksandra V Sen'kova, Valeriy P Nikolin, Nelly A Popova, Marina A Zenkova, Valentin V Vlassov, Elena L Chernolovskaya
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150751 (2016)
Small interfering RNAs, depending on their structure, delivery system and sequence, can stimulate innate and adaptive immunity. The aim of this study was to investigate the antitumor and antimetastatic effects of immunostimulatory 19-bp dsRNA with 3'
Externí odkaz:
https://doaj.org/article/cfe2610b869640afabc544a72fe31276
Autor:
Vera S, Ruzanova, Anastasia S, Proskurina, Genrikh S, Ritter, Yaroslav R, Efremov, Valeriy P, Nikolin, Nelly A, Popova, Vasiliy A, Naprimerov, Evgenia V, Dolgova, Ekaterina A, Potter, Svetlana S, Kirikovich, Evgeniy V, Levites, Zakhar S, Mustafin, Sergey A, Lashin, Ekaterina A, Burakova, Dmitry A, Stetsenko, Alexandr A, Ostanin, Elena R, Chernykh, Sergey S, Bogachev
Publikováno v:
Anticancer research. 41(7)
We compared the therapeutic efficacy of two recently developed experimental anticancer technologies: 1) in situ vaccination based on local immunotherapy with CpG oligonucleotides and anti-OX40 antibodies to activate antitumor immune response and 2) "
Autor:
Genrikh S, Ritter, Valeriy P, Nikolin, Nelly A, Popova, Anastasia S, Proskurina, Polina E, Kisaretova, Oleg S, Taranov, Tatiana D, Dubatolova, Evgenia V, Dolgova, Ekaterina A, Potter, Svetlana S, Kirikovich, Yaroslav R, Efremov, Sergey I, Bayborodin, Margarita V, Romanenko, Maria I, Meschaninova, Aliya G, Venyaminova, Nikolay A, Kolchanov, Mikhail A, Shurdov, Sergey S, Bogachev
Publikováno v:
International journal of radiation biology. 96(9)
Protection from ionizing radiation is the most important component in the curing malignant neoplasms, servicing atomic reactors, and resolving the situations associated with uncontrolled radioactive pollutions. In this regard, discovering new effecti
Autor:
Jóhannes Reynisson, Raina Chand, Daniel M Ayine-Tora, Valeriy P. Nikolin, Olga D. Zakharova, Ekaterina S Ilina, Dina V. Korchagina, Olga I. Lavrik, Jinal Patel, Alexandra L. Zakharenko, N.F. Salakhutdinov, Arina A Chepanova, V. I. Kaledin, T. M. Khomenko, Konstantin P. Volcho, Ivanhoe K. H. Leung, Nelly A Popova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 126 (2019)
International Journal of Molecular Sciences; Volume 21; Issue 1; Pages: 126
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 21; Issue 1; Pages: 126
International Journal of Molecular Sciences
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is an important DNA repair enzyme in humans, and a current and promising inhibition target for the development of new chemosensitizing agents due to its ability to remove DNA damage caused by topoisomerase 1 (To