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pro vyhledávání: '"Valeriy Afonin"'
Autor:
James A. Swenberg, Rhoderick H. Elder, Valeriy Afonin, Keizo Tano, Jun Nakamura, Shunichi Takeda, Masami Watanabe, Brian F. Pachkowski
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 671:93-99
Poly(ADP-ribose) polymerase-1 (PARP-1) is a base excision repair (BER) protein that binds to DNA single strand breaks (SSBs) and subsequently synthesizes and transfers poly(ADP-ribose) polymers to various nuclear proteins. Numerous biochemical studie