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of 6
pro vyhledávání: '"Valeriu Bortnov"'
Autor:
Valeriu Bortnov, Marco Tonelli, Woonghee Lee, Ziqing Lin, Douglas S. Annis, Omar N. Demerdash, Alex Bateman, Julie C. Mitchell, Ying Ge, John L. Markley, Deane F. Mosher
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Myeloid-derived growth factor (MYDGF) is an endoplasmic reticulum protein of therapeutic interest because it promotes tissue repair in a murine model of myocardial infarction. Here the authors present the NMR structure of human MYDGF and attribute fu
Externí odkaz:
https://doaj.org/article/a6990a6e878247dcb11d2880bc0fb764
Autor:
Oscar Mulvaney, Valeriu Bortnov, Ruth A. Houseright, Anna Huttenlocher, Deane F. Mosher, Julie Rindy, Veronika Miskolci, David A. Bennin
Publikováno v:
The Journal of Cell Biology
This study shows that MYDGF regulates neutrophil behavior in response to tissue damage but not microbial cues. The findings suggest that MYDGF promotes wound healing in larval zebrafish by providing a brake on neutrophil inflammation.
Neutrophil
Neutrophil
Autor:
Woonghee Lee, Ziqing Lin, Alex Bateman, Omar Demerdash, Deane F. Mosher, Julie C. Mitchell, Valeriu Bortnov, Ying Ge, John L. Markley, Marco Tonelli, Douglas S. Annis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Human myeloid-derived growth factor (hMYDGF) is a 142-residue protein with a C-terminal endoplasmic reticulum (ER) retention sequence (ERS). Extracellular MYDGF mediates cardiac repair in mice after anoxic injury. Although homologs of hMYDGF are foun
Autor:
Karina T. Barretto, Frances J. Fogerty, Douglas S. Annis, Valeriu Bortnov, Keren B. Turton, Deane F. Mosher
Publikováno v:
Journal of Biological Chemistry. 293:13166-13175
Human myeloid-derived growth factor (MYDGF; also known as C19orf10) is named based on its identification as a secreted monocyte/macrophage–derived mediator of cardiac repair following myocardial infarction in mice. Homologs of MYDGF, however, are p
Autor:
Mats W. Johansson, Christopher L. Nguyen, Deane F. Mosher, Valeriu Bortnov, Manav Khanna, Douglas S. Annis
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 47(10)
SummaryBackground IL-5 causes suspended eosinophils to polarize with filamentous (F)-actin and granules at one pole and the nucleus in a specialized uropod, the “nucleopod,” which is capped with P-selectin glycoprotein ligand-1 (PSGL-1). IL-5 enh
Akademický článek
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