Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Valerio W. Valeri"'
1
Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques
Autor: Valentina Cecchinato, Jean-Michel Heraud, Gary Landucci, Stephen Whitney, Vibeke Andresen, Ruth H. Florese, Janos Nacsa, Izabela Bialuk, Thorsten Demberg, Marjorie Robert Guroff, Robyn Washington Parks, Donald N. Forthal, David Venzon, Shari N. Gordon, Genoveffa Franchini, Valerio W. Valeri, David C. Montefiori
Publikováno v: Vaccine
Vaccine, Elsevier, 2011, 30 (1), pp.78-94. ⟨10.1016/j.vaccine.2011.10.040⟩
International audience; The role of antibodies directed against the hyper variable envelope region V1 of human immunode-ficiency virus type 1 (HIV-1), has not been thoroughly studied. We show that a vaccine able to elicit strain-specific non-neutrali
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90877bb81f0c5465649c2d6e2a8789b4
https://doi.org/10.1016/j.vaccine.2011.10.040
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2
Suppression of HTLV-1 replication by Tax-mediated rerouting of the p13 viral protein to nuclear speckles
Autor: Marcia Bellon, Valentina Cecchinato, Genoveffa Franchini, Risaku Fukumoto, Uma Sinha-Datta, Cynthia A. Pise-Masison, Robyn Washington Parks, Vibeke Andresen, Christophe Nicot, Valerio W. Valeri
Publikováno v: Blood. 118:1549-1559
Disease development in human T-cell leukemia virus type 1 (HTLV-1)–infected individuals is positively correlated with the level of integrated viral DNA in T cells. HTLV-1 replication is positively regulated by Tax and Rex and negatively regulated b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85caff135921e88c1e9891d57973cc4c
https://doi.org/10.1182/blood-2010-06-293340
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3
Inhibition of T-Cell Receptor Signal Transduction and Viral Expression by the Linker for Activation of T Cells-Interacting p12 I Protein of Human T-Cell Leukemia/Lymphoma Virus Type 1
Autor: Miroslav Dundr, Christophe Nicot, Valerio W. Valeri, Genoveffa Franchini, Risaku Fukumoto, Anthony Adams, Lawrence E. Samelson
Publikováno v: Journal of Virology. 81:9088-9099
The p12 I protein of human T-cell leukemia/lymphoma virus type 1 (HTLV-1) is a small oncoprotein that increases calcium release following protein kinase C activation by phorbol myristate acetate, and importantly, this effect is linker for activation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1891d3af62754e81f95a4d89d823b0
https://doi.org/10.1128/jvi.02703-06
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4
HTLV-1 p12I and p30II proteins in viral persistence and pathogenesis
Autor: Genoveffa Franchini, Risaku Fukumoto, Mirek Dundr, Valerio W. Valeri
Publikováno v: Brazilian Journal of Infectious Diseases, Vol 9, Iss 5, Pp 447-449
The TP53 gene encodes a nuclear protein implicated in the regulation of the cell cycle, DNA repair, and apoptosis. TP53 mutations and other alterations have been described in numerous types of tumors, and some of these have been associated with poor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251f15f8a6df7210a1f0be8145a25d22
https://doi.org/10.1590/s1413-86702005000500031
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6
In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12I protein
Autor: Genoveffa Franchini, Julie M. Nauroth, Valentina Cecchinato, Izabela Bialuk, Vibeke Andresen, Jean Claude Walser, Antoine Gessain, Christophe Nicot, Valerio W. Valeri, Risaku Fukumoto
Publikováno v: Blood
Blood, American Society of Hematology, 2009, 113 (16), pp.3726-34. ⟨10.1182/blood-2008-04-146928⟩
Blood, 2009, 113 (16), pp.3726-34. ⟨10.1182/blood-2008-04-146928⟩
The human T-cell leukemia/lymphoma virus Type 1 (HTLV-1) ORF-I encodes, a ninety-nine amino acid hydrophobic membrane protein, p12I that affects receptors in different cellular compartments. We report here that proteolytic cleavage dictates different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c511e0aa11ea2e4f7b4f9e2af6c66ecc
https://hal-pasteur.archives-ouvertes.fr/pasteur-00531275
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7
HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques
Autor: Jean-Philippe Herbeuval, Jan Andersson, Jakob Nilsson, Genoveffa Franchini, Valentina Cecchinato, Andrew W. Hardy, Adriano Boasso, Gene M. Shearer, Monica Vaccari, Valerio W. Valeri
Publikováno v: AIDS
Objective: To determine how antiretroviral therapy (ART) or HAART affects the expression of apoptotic ligands and their death receptors in the blood and lymphoid tissuesofHIV-infectedpatientsandsimianimmunodeficiencyvirus-infectedmacaques. Methods: W
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c0281ea214c3fe34afd42780252c05
https://pubmed.ncbi.nlm.nih.gov/19050384
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8
Identification of novel monocistronic HTLV-1 mRNAs encoding functional Rex isoforms
Autor: Ilaria Cavallari, Genoveffa Franchini, Valerio W Valeri, Vincenzo Ciminale, Vibeke Andresen, Francesca Rende, Donna M. D'Agostino
Publikováno v: Retrovirology
Background: Human T cell leukemia virus type 1 (HTLV-1) gene expression is controlled by the key regulatory proteins Tax and Rex. The concerted action of these proteins results in a two-phase kinetics of viral expression that depends on a time delay
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4bd7626fe9c36466ff71c1954970e8
http://europepmc.org/articles/PMC4577747
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