Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Valerio Secli"'
Autor:
Valerio Secli, Emma Michetti, Francesca Pacello, Federico Iacovelli, Mattia Falconi, Maria Luisa Astolfi, Daniela Visaggio, Paolo Visca, Serena Ammendola, Andrea Battistoni
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Limiting the availability of transition metals at infection sites serves as a critical defense mechanism employed by the innate immune system to combat microbial infections. Pseudomonas aeruginosa exhibits a remarkable ability to thrive in z
Externí odkaz:
https://doaj.org/article/42842d08acb14d8e804bf61e9b8c395c
Autor:
Marsha Pellegrino, Valerio Secli, Silvia D’Amico, Lucia Lisa Petrilli, Matteo Caforio, Valentina Folgiero, Nicola Tumino, Paola Vacca, Maria Vinci, Doriana Fruci, Emmanuel de Billy
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cancer immunotherapy has made impressive advances in improving the outcome of patients affected by malignant diseases. Nonetheless, some limitations still need to be tackled to more efficiently and safely treat patients, in particular for those affec
Externí odkaz:
https://doaj.org/article/f72a5d87ecd6417d9377f84abca421f8
Autor:
Valerio Secli, Claudia Di Biagio, Arianna Martini, Emma Michetti, Francesca Pacello, Serena Ammendola, Andrea Battistoni
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 944 (2023)
The innate immune responses of mammals to microbial infections include strategies based on manipulating the local concentration of metals such as iron (Fe) and zinc (Zn), commonly described as nutritional immunity. To evaluate whether these strategie
Externí odkaz:
https://doaj.org/article/a84a50e12acf47feba988f5f25d7742d
Autor:
Serena Ammendola, Valerio Secli, Francesca Pacello, Martina Bortolami, Fabiana Pandolfi, Antonella Messore, Roberto Di Santo, Luigi Scipione, Andrea Battistoni
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10217 (2021)
The ability to obtain Fe is critical for pathogens to multiply in their host. For this reason, there is significant interest in the identification of compounds that might interfere with Fe management in bacteria. Here we have tested the response of t
Externí odkaz:
https://doaj.org/article/e7a663e342854c1f8861df4c1978a7cc
Autor:
Serena Ammendola, Valerio Secli, Francesca Pacello, Maria Chiara Mastropasqua, Mariana A Romão, Cláudio M Gomes, Andrea Battistoni
Pseudomonas aeruginosa is known to exhibit considerable resistance to the antimicrobial activity of the metal-sequestering protein calprotectin (CP). In this study, we demonstrate that although CP induces zinc deficiency in P. aeruginosa, a strain un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310bcef4791d7654c34bd71d4fbfc9ed
https://hdl.handle.net/2108/310776
https://hdl.handle.net/2108/310776
Autor:
Nicola Demitri, Valerio Secli, Francesca Cutruzzolà, Serena Ammendola, Serena Rinaldo, Andrea Ilari, Annarita Fiorillo, Andrea Battistoni
Publikováno v:
'Acta Crystallographica D ', vol: 77, pages: 1401-1410 (2021)
Acta Crystallographica. Section D, Structural Biology
Acta Crystallographica. Section D, Structural Biology
The structural and zinc-binding properties of PA4063, one of the periplasmic proteins expressed by Pseudomonas aeruginosa under zinc-deficient conditions, are presented. PA4063 has a noncanonical ferredoxin-like fold. Two zinc-binding sites with micr
Autor:
Andrea Battistoni, Serena Ammendola, Francesca Pacello, Roberto Di Santo, Luigi Scipione, Fabiana Pandolfi, Valerio Secli, Martina Bortolami, Antonella Messore
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10217, p 10217 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10217, p 10217 (2021)
The ability to obtain Fe is critical for pathogens to multiply in their host. For this reason, there is significant interest in the identification of compounds that might interfere with Fe management in bacteria. Here we have tested the response of t
Autor:
Secli, Valerio1 (AUTHOR), Di Biagio, Claudia2 (AUTHOR), Martini, Arianna2,3 (AUTHOR), Michetti, Emma1 (AUTHOR), Pacello, Francesca1 (AUTHOR), Ammendola, Serena1 (AUTHOR), Battistoni, Andrea1 (AUTHOR) andrea.battistoni@uniroma2.it
Publikováno v:
International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 2, p944. 12p.
Autor:
Fiorillo, Annarita1,2 (AUTHOR) annarita.fiorillo@uniroma1.it, Battistoni, Andrea3 (AUTHOR), Ammendola, Serena3 (AUTHOR), Secli, Valerio3 (AUTHOR), Rinaldo, Serena1,4 (AUTHOR), Cutruzzolà, Francesca1,4 (AUTHOR), Demitri, Nicola5 (AUTHOR), Ilari, Andrea2 (AUTHOR)
Publikováno v:
Acta Crystallographica: Section D, Structural Biology. Nov2021, Vol. 77 Issue 11, p1401-1410. 10p.
Publikováno v:
Immunotherapy Weekly; 2024, p185-185, 1p