Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Valerio Di Carlo"'
Autor:
Damiano Mangoni, Alessandro Simi, Pierre Lau, Alexandros Armaos, Federico Ansaloni, Azzurra Codino, Devid Damiani, Lavinia Floreani, Valerio Di Carlo, Diego Vozzi, Francesca Persichetti, Claudio Santoro, Luca Pandolfini, Gian Gaetano Tartaglia, Remo Sanges, Stefano Gustincich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Long Interspersed Nuclear Elements-1s (L1s) are transposable elements that constitute most of the genome’s transcriptional output yet have still largely unknown functions. Here we show that L1s are required for proper mouse brain corticoge
Externí odkaz:
https://doaj.org/article/66f2f44858894eb082807efecd36e486
Autor:
Valeria Ruggiero, Claudio Fagioli, Stefano de Pretis, Valerio Di Carlo, Nicoletta Landsberger, Daniele Zacchetti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
CDKL5 is a kinase with relevant functions in correct neuronal development and in the shaping of synapses. A decrease in its expression or activity leads to a severe neurodevelopmental condition known as CDKL5 deficiency disorder (CDD). CDD arises fro
Externí odkaz:
https://doaj.org/article/3561e301f749442799dc30d47326ef82
Autor:
Raquel García-Pérez, Paula Esteller-Cucala, Glòria Mas, Irene Lobón, Valerio Di Carlo, Meritxell Riera, Martin Kuhlwilm, Arcadi Navarro, Antoine Blancher, Luciano Di Croce, José Luis Gómez-Skarmeta, David Juan, Tomàs Marquès-Bonet
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamic
Externí odkaz:
https://doaj.org/article/60968dc22fd449f3aebdf1675cc35a52
Autor:
Julie Martone, Michela Lisi, Francesco Castagnetti, Alessandro Rosa, Valerio Di Carlo, Enrique Blanco, Adriano Setti, Davide Mariani, Alessio Colantoni, Tiziana Santini, Lucia Perone, Luciano Di Croce, Irene Bozzoni
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Abstract Exon skipping is an effective strategy for the treatment of many Duchenne Muscular Dystrophy (DMD) mutations. Natural exon skipping observed in several DMD cases can help in identifying novel therapeutic tools. Here, we show a DMD study case
Externí odkaz:
https://doaj.org/article/7c39711dad2b4a2b8f5aa3dfa9d3a1bb
Autor:
Angelisa Frasca, Eleonora Spiombi, Michela Palmieri, Elena Albizzati, Maria Maddalena Valente, Anna Bergo, Barbara Leva, Charlotte Kilstrup‐Nielsen, Federico Bianchi, Valerio Di Carlo, Ferdinando Di Cunto, Nicoletta Landsberger
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 6, Pp n/a-n/a (2020)
Abstract Mutations in MECP2 cause several neurological disorders of which Rett syndrome (RTT) represents the best‐defined condition. Although mainly working as a transcriptional repressor, MeCP2 is a multifunctional protein revealing several activi
Externí odkaz:
https://doaj.org/article/b33103f72f62419ba99b856dddd50402
Autor:
Laura Pascual-Reguant, Enrique Blanco, Silvia Galan, François Le Dily, Yasmina Cuartero, Gemma Serra-Bardenys, Valerio Di Carlo, Ane Iturbide, Joan Pau Cebrià-Costa, Lara Nonell, Antonio García de Herreros, Luciano Di Croce, Marc A. Marti-Renom, Sandra Peiró
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Lamina-associated domains (LADs) contact lamins in the nuclear lamina, and lamin B1 was thought to bind heterochromatic regions at the nuclear envelope. Here, the authors show lamin B1 associates with actively expressed euchromatin regions, creating
Externí odkaz:
https://doaj.org/article/78004395e63b43cd90af855de0989ca6
Autor:
Elena Tassi, Marco Braga, Renato Longhi, Francesca Gavazzi, Giorgio Parmiani, Valerio Di Carlo, Maria Pia Protti
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7234 (2009)
BACKGROUND: Pancreatic cancer is a very aggressive disease with dismal prognosis; peculiar is the tumor microenvironment characterized by an extensive fibrotic stroma, which favors rapid tumor progression. We previously reported that pancreatic cance
Externí odkaz:
https://doaj.org/article/73b059353cfa4cde8a675a8bc355ead1
Autor:
Paola Maffi, Enzo Angeli, Federico Bertuzzi, Carlo Paties, Carlo Socci, Carlo Fedeli, Francesca De Taddeo, Rita Nano, Valerio Di Carlo, Alessandro Del Maschio, Antonio Secchi
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Several reports have been published on islet transplantation in humans, but few data are available on the effect of islet infusion on the hepatic structure. Our aim was to evaluate in a longitudinal study the impact on the liver of intrahepatic islet
Externí odkaz:
https://doaj.org/article/e771927038264d9382f78d7e3f61652e
Autor:
Ennio La Rocca, Paolo Fiorina, Ettore Astorri, Claudio Rossetti, Giovanni Lucignani, Ferruccio Fazio, Daniela Giudici, Renato Castoldi, Giuseppe Bianchi, Valerio Di Carlo, Guido Pozza, Antonio Secchi M.D.
Publikováno v:
Cell Transplantation, Vol 9 (2000)
In diabetic patients cardiovascular morbidity and mortality is still a major problem. Our aim was to study the effect of kidney–pancreas transplantation on survival, cardiovascular events, and causes of death in diabetic type I uremic patients. Thr
Externí odkaz:
https://doaj.org/article/1c66df2f56954488bad852a3685f3c52
Autor:
Lucio Scopsi M.D., D.M.Sc., Salvatore Andreola, Carlo Socci, Federico Bertuzzi, Valerio Di Carlo, Guido Pozza, Franco Rilke, Leandro Gennari, Giovanni Coleela, Enrico Regalia, Vincenzo Mazzaferro
Publikováno v:
Cell Transplantation, Vol 3 (1994)
The unique availability of an explanted liverislet allograft, removed for primary nonfunction of the liver, led us to evaluate distribution and phenotype of exocrine and endocrine components of the pancreatic graft. Immunocytochemistry was used to ma
Externí odkaz:
https://doaj.org/article/7340ac73d4aa4249a2dc1c75443e25ec