Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Valerio Del Vescovo"'
miR375-3p Distinguishes Low-Grade Neuroendocrine From Non-neuroendocrine Lung Tumors in FFPE Samples
Autor:
Simone Detassis, Valerio del Vescovo, Margherita Grasso, Stefania Masella, Chiara Cantaloni, Luca Cima, Alberto Cavazza, Paolo Graziano, Giulio Rossi, Mattia Barbareschi, Leonardo Ricci, Michela Alessandra Denti
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Lung cancer is still one of the leading cause of death worldwide. The clinical variability of lung cancer is high and drives treatment decision. In this context, correct discrimination of pulmonary neuroendocrine tumors is still of critical relevance
Externí odkaz:
https://doaj.org/article/25210183428346f3aa3123f8a96831b4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Since their discovery and the advent of RNA interference, microRNAs have drawn enormous attention because of their ubiquitous involvement in cellular pathways from life to death, from metabolism to communication. It is also widely accepted that they
Externí odkaz:
https://doaj.org/article/a2788f8fbf5d4f25bd3c079fd1f3bc77
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78870 (2013)
Non-coding RNAs play major roles in the translational control of gene expression. In order to identify disease-associated miRNAs in precursor lesions of lung cancer, RNA extracts from lungs of either c-Raf transgenic or wild-type (WT) mice were hybri
Externí odkaz:
https://doaj.org/article/85d4c729fae34e56987da0d7bb52cf3e
Autor:
Lucia Piacentini, Laura Fanti, Rodolfo Negri, Valerio Del Vescovo, Alessandro Fatica, Fabio Altieri, Sergio Pimpinelli
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000670 (2009)
Heterochromatin Protein 1 (HP1a) is a well-known conserved protein involved in heterochromatin formation and gene silencing in different species including humans. A general model has been proposed for heterochromatin formation and epigenetic gene sil
Externí odkaz:
https://doaj.org/article/ad74b53f146749a0aecaa47542ddfca0
Autor:
Ilaria Castiglioni, Federica Babbio, Lina Sabatino, Francesca Precazzini, Monica Mancini, Margherita Grasso, Michela A. Denti, Michele Zocchi, Valentina Zanetti, Ian Marc Bonapace, Alessandro Weisz, Valerio Licursi, Valerio Del Vescovo, Francesca Rizzo, Maria Giovanna De Marino, Livio Muccillo, Christian Pistore, Paola Chiarugi, Giorgio Giurato
Publikováno v:
Carcinogenesis. 42(12)
Epithelial-to-mesenchymal transition (EMT) is involved in prostate cancer (PCa) metastatic progression, and its plasticity suggests epigenetic implications. Deregulation of DNA methyltransferases (DNMTs) and several microRNAs (miRNAs) plays a relevan
miR375-3p Distinguishes Low-Grade Neuroendocrine From Non-neuroendocrine Lung Tumors in FFPE Samples
Autor:
Simone Detassis, Valerio del Vescovo, Margherita Grasso, Stefania Masella, Chiara Cantaloni, Luca Cima, Alberto Cavazza, Paolo Graziano, Giulio Rossi, Mattia Barbareschi, Leonardo Ricci, Michela Alessandra Denti
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 7 (2020)
Frontiers in Molecular Biosciences, Vol 7 (2020)
Lung cancer is still one of the leading cause of death worldwide. The clinical variability of lung cancer is high and drives treatment decision. In this context, correct discrimination of pulmonary neuroendocrine tumors is still of critical relevance
Autor:
Aldina Venerosi, Valerio Del Vescovo, Annamaria Confaloni, Alessio Crestini, Catherine M. Greene, Paola Piscopo, Michela A. Denti, Gemma Calamandrei, Sebastian Vencken, Margherita Grasso, Francesca Fontana, Maria Puopolo
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Progranulin (PGRN) is a secreted protein expressed ubiquitously throughout the body, including the brain, where it localizes in neurons and is activated microglia. Loss-of-function mutations in the GRN gene are an important cause of familial frontote
Autor:
S. Moncini, Paola Riva, Alice Valmadre, Marco Venturin, Marta Lunghi, Michela A. Denti, Valerio Del Vescovo, Margherita Grasso
Cyclin-dependent kinase 5 regulatory subunit 1 (CDK5R1) encodes p35, the main activatory subunit of cyclin-dependent kinase 5 (CDK5). The p35/CDK5 active complex plays a fundamental role in brain development and functioning, but its deregulated activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e9710932bdf7b9b5df18f98c45acff
http://hdl.handle.net/11572/175344
http://hdl.handle.net/11572/175344
Autor:
Valerio, Del Vescovo, Michela A, Denti
Publikováno v:
Advances in experimental medicine and biology. 889
Lung cancer is the leading cause of cancer mortality worldwide. microRNAs (miRNAs) have been established as players with a relevant role in lung cancer development, epithelial-mesenchymal transition and response to therapy. Additionally, in the last
Autor:
Massimo Silvestri, Rodolfo Carella, Mattia Barbareschi, Alberto Cucino, Alberto Cavazza, Valentina Monica, Giuseppe Pelosi, Paolo Palma, Claudio Doglioni, Paolo Graziano, Valerio Del Vescovo, Luca Morelli, Michela A. Denti, Giulio Rossi, Giuseppe Tirone, Mauro Papotti, Chiara Cantaloni
Publikováno v:
American Journal of Clinical Pathology. 136:773-782
Large cell carcinomas (LCCs) of the lung are heterogeneous and may be of different cell lineages. We analyzed 56 surgically resected lung tumors classified as LCC on the basis of pure morphologic grounds, using a panel of immunophenotypic markers (ad