Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Valerio Consalvi"'
Autor:
Maria Petrosino, Leonore Novak, Alessandra Pasquo, Paola Turina, Emidio Capriotti, Velia Minicozzi, Valerio Consalvi, Roberta Chiaraluce
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-23 (2023)
Abstract Mitogen-activated protein kinases 1 and 3 (MAPK1 and MAPK3), also called extracellular regulated kinases (ERK2 and ERK1), are serine/threonine kinase activated downstream by the Ras/Raf/MEK/ERK signal transduction cascade that regulates a va
Externí odkaz:
https://doaj.org/article/629e896713a64b7e8fe68e4a682f963a
Autor:
Tiziana Sanavia, Paola Turina, Silvia Morante, Valerio Consalvi, Arthur M. Lesk, Constantina Bakolitsa, Daniele Dell'Orco
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/c72a524a5e7f42f485febcbd61f0b19a
Autor:
Dr. Maria Petrosino, Dr. Francesco Stellato, Prof. Roberta Chiaraluce, Prof. Valerio Consalvi, Dr. Giovanni La Penna, Dr. Alessandra Pasquo, Dr. Olivier Proux, Prof. Giancarlo Rossi, Prof. Silvia Morante
Publikováno v:
ChemistryOpen, Vol 10, Iss 11, Pp 1133-1141 (2021)
Abstract We present in this work a first X‐ray Absorption Spectroscopy study of the interactions of Zn with human BST2/tetherin and SARS‐CoV‐2 orf7a proteins as well as with some of their complexes. The analysis of the XANES region of the measu
Externí odkaz:
https://doaj.org/article/c57e1b68b9544cddb68fcd95f0b07719
Autor:
Tecla Ciociola, Laura Giovati, Tiziano De Simone, Greta Bergamaschi, Alessandro Gori, Valerio Consalvi, Stefania Conti, Alberto Vitali
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 472 (2023)
Antimicrobial resistance is a major public health concern worldwide. Albeit to a lesser extent than bacteria, fungi are also becoming increasingly resistant to antifungal drugs. Moreover, due to the small number of antifungal classes, therapy options
Externí odkaz:
https://doaj.org/article/743c7a4a71804ef58e96b37731350c60
Autor:
Leonore Novak, Maria Petrosino, Alessandra Pasquo, Apirat Chaikuad, Roberta Chiaraluce, Stefan Knapp, Valerio Consalvi
Publikováno v:
Cancers; Volume 15; Issue 11; Pages: 2938
The extracellular-signal-regulated kinase 2 (ERK2), a mitogen-activated protein kinase (MAPK) located downstream of the Ras-Raf-MEK-ERK signal transduction cascade, is involved in the regulation of a large variety of cellular processes. The ERK2, act
Autor:
Maria Petrosino, Leonore Novak, Alessandra Pasquo, Roberta Chiaraluce, Paola Turina, Emidio Capriotti, Valerio Consalvi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5416 (2021)
Large scale genome sequencing allowed the identification of a massive number of genetic variations, whose impact on human health is still unknown. In this review we analyze, by an in silico-based strategy, the impact of missense variants on cancer-re
Externí odkaz:
https://doaj.org/article/5a0b3dd509aa49b68568b223c8072a6f
Autor:
Leonore Novak, Maria Petrosino, Daniele Santorelli, Roberta Chiaraluce, Valerio Consalvi, Alessandra Pasquo, Carlo Travaglini-Allocatelli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5953 (2021)
Bromodomains (BRDs) are small protein interaction modules of about 110 amino acids that selectively recognize acetylated lysine in histones and other proteins. These domains have been identified in a variety of multi-domain proteins involved in trans
Externí odkaz:
https://doaj.org/article/928f6a43d5b34ed1a594a86fde683c64
Autor:
Maria Petrosino, Daniela Bonetti, Alessandra Pasquo, Laura Lori, Roberta Chiaraluce, Valerio Consalvi, Carlo Travaglini-Allocatelli
Publikováno v:
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 99-104 (2017)
Bromodomains (BRDs) are small protein domains often present in large multidomain proteins involved in transcriptional regulation in eukaryotic cells. They currently represent valuable targets for the development of inhibitors of aberrant transcriptio
Externí odkaz:
https://doaj.org/article/7301862b8af74c558bcd25801b07fa67
Autor:
Annarita Fiorillo, Maria Petrosino, Andrea Ilari, Alessandra Pasquo, Alessandra Cipollone, Maristella Maggi, Roberta Chiaraluce, Valerio Consalvi
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199191 (2018)
Cancer cells are able to survive in difficult conditions, reprogramming their metabolism according to their requirements. Under hypoxic conditions they shift from oxidative phosphorylation to aerobic glycolysis, a behavior known as Warburg effect. In
Externí odkaz:
https://doaj.org/article/aea6a3fc775d4c81a31610ead4b83318
Autor:
Olivier Proux, Giancarlo Rossi, Giovanni La Penna, Alessandra Pasquo, Silvia Morante, Maria Petrosino, Valerio Consalvi, Francesco Stellato, Roberta Chiaraluce
Publikováno v:
'ChemistryOpen ', vol: 10, pages: 1133-1141 (2021)
ChemistryOpen, Vol 10, Iss 11, Pp 1133-1141 (2021)
ChemistryOpen 10 (2021): 1133–1141. doi:10.1002/open.202100217
info:cnr-pdr/source/autori:Petrosino M.; Stellato F.; Chiaraluce R.; Consalvi V.; La Penna G.; Pasquo A.; Proux O.; Rossi G.; Morante S./titolo:Zn-Induced Interactions Between SARS-CoV-2 orf7a and BST2%2FTetherin/doi:10.1002%2Fopen.202100217/rivista:ChemistryOpen/anno:2021/pagina_da:1133/pagina_a:1141/intervallo_pagine:1133–1141/volume:10
ChemistryOpen
ChemistryOpen, Vol 10, Iss 11, Pp 1133-1141 (2021)
ChemistryOpen 10 (2021): 1133–1141. doi:10.1002/open.202100217
info:cnr-pdr/source/autori:Petrosino M.; Stellato F.; Chiaraluce R.; Consalvi V.; La Penna G.; Pasquo A.; Proux O.; Rossi G.; Morante S./titolo:Zn-Induced Interactions Between SARS-CoV-2 orf7a and BST2%2FTetherin/doi:10.1002%2Fopen.202100217/rivista:ChemistryOpen/anno:2021/pagina_da:1133/pagina_a:1141/intervallo_pagine:1133–1141/volume:10
ChemistryOpen
We present in this work a first X‐ray Absorption Spectroscopy study of the interactions of Zn with human BST2/tetherin and SARS‐CoV‐2 orf7a proteins as well as with some of their complexes. The analysis of the XANES region of the measured spect