Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Valerio, Orlando"'
Autor:
Daniela Laricchiuta, Juliette Gimenez, Giuseppe Sciamanna, Andrea Termine, Carlo Fabrizio, Francesco Della Valle, Silvia Caioli, Luana Saba, Marco De Bardi, Francesca Balsamo, Anna Panuccio, Noemi Passarello, Anna Mattioni, Elisa Bisicchia, Cristina Zona, Valerio Orlando, Laura Petrosini
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113066- (2023)
Summary: Fear-related disorders arise from inefficient fear extinction and have immeasurable social and economic costs. Here, we characterize mouse phenotypes that spontaneously show fear-independent behavioral traits predicting adaptive or maladapti
Externí odkaz:
https://doaj.org/article/69ffa47c14ec4525be678e28489ac160
Autor:
Jacob G. Smith, Kevin B. Koronowski, Thomas Mortimer, Tomoki Sato, Carolina M. Greco, Paul Petrus, Amandine Verlande, Siwei Chen, Muntaha Samad, Ekaterina Deyneka, Lavina Mathur, Ronnie Blazev, Jeffrey Molendijk, Arun Kumar, Oleg Deryagin, Mireia Vaca-Dempere, Valentina Sica, Peng Liu, Valerio Orlando, Benjamin L. Parker, Pierre Baldi, Patrick-Simon Welz, Cholsoon Jang, Selma Masri, Salvador Aznar Benitah, Pura Muñoz-Cánoves, Paolo Sassone-Corsi
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112588- (2023)
Summary: Physiology is regulated by interconnected cell and tissue circadian clocks. Disruption of the rhythms generated by the concerted activity of these clocks is associated with metabolic disease. Here we tested the interactions between clocks in
Externí odkaz:
https://doaj.org/article/da43be69311647c3a3d0a4fdfd5731ef
Autor:
Juliette Gimenez, Alida Spalloni, Sara Cappelli, Francesca Ciaiola, Valerio Orlando, Emanuele Buratti, Patrizia Longone
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13807 (2023)
Since its initial involvement in numerous neurodegenerative pathologies in 2006, either as a principal actor or as a cofactor, new pathologies implicating transactive response (TAR) DNA-binding protein 43 (TDP-43) are regularly emerging also beyond t
Externí odkaz:
https://doaj.org/article/ceb7ab62b53c46e68b96ce1661a3be4d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Non-coding DNA accounts for approximately 98.5% of the human genome. Once labeled as “junk DNA”, this portion of the genome has undergone a progressive re-evaluation and it is now clear that some of its transcriptional products, belonging to the
Externí odkaz:
https://doaj.org/article/1e7e1e061ae64a04b02106f95851ad00
Autor:
Nadine Hosny El Said, Francesco Della Valle, Peng Liu, Andreu Paytuví-Gallart, Sabir Adroub, Juliette Gimenez, Valerio Orlando
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-10 (2021)
Abstract PRC2-mediated epigenetic function involves the interaction with long non-coding RNAs (lncRNAs). Although the identity of some of these RNAs has been elucidated in the context of developmental programs, their counterparts in postmitotic adult
Externí odkaz:
https://doaj.org/article/014c3dad10014b12873ff4f11517308b
Autor:
Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki, Kosuke Hashimoto, Giovanni Pascarella, Juliette Gimenez, Leonie Roos, Alex J. Nash, Marco Ghilotti, Christopher J. F. Cameron, Matthew Valentine, Yulia A. Medvedeva, Shuhei Noguchi, Eneritz Agirre, Kaori Kashi, Samudyata, Joachim Luginbühl, Riccardo Cazzoli, Saumya Agrawal, Nicholas M. Luscombe, Mathieu Blanchette, Takeya Kasukawa, Michiel de Hoon, Erik Arner, Boris Lenhard, Charles Plessy, Gonçalo Castelo-Branco, Valerio Orlando, Piero Carninci
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Mammalian genomes encode tens of thousands of ncRNAs that have important roles in regulation of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin interactions in intact nuclei to shed light on these
Externí odkaz:
https://doaj.org/article/3ee35708eeee438bbb6649cdd0169ea5
Autor:
Francesco Della Valle, Manjula P. Thimma, Massimiliano Caiazzo, Salvatore Pulcrano, Mirko Celii, Sabir A. Adroub, Peng Liu, Gregorio Alanis-Lobato, Vania Broccoli, Valerio Orlando
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 60-74 (2020)
Summary: In mammals, LINE-1 (L1) retrotransposons constitute between 15% and 20% of the genome. Although only a few copies have retained the ability to retrotranspose, evidence in brain and differentiating pluripotent cells indicates that L1 retrotra
Externí odkaz:
https://doaj.org/article/5b877dab7e3747c58a1c35b460267621
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-13 (2019)
Abstract Background While the role of Polycomb group protein-mediated “cell memory” is well established in developmental contexts, little is known about their role in adult tissues and in particular in post-mitotic cells. Emerging evidence assign
Externí odkaz:
https://doaj.org/article/be85711e412b4c5586a9dbe74856e14c
Autor:
Andrea Termine, Carlo Fabrizio, Juliette Gimenez, Anna Panuccio, Francesca Balsamo, Noemi Passarello, Silvia Caioli, Luana Saba, Marco De Bardi, Francesco Della Valle, Valerio Orlando, Laura Petrosini, Daniela Laricchiuta
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2538 (2022)
Approach and avoidance (A/A) tendencies are stable behavioral traits in responding to rewarding and fearful stimuli. They represent the superordinate division of emotion, and individual differences in such traits are associated with disease susceptib
Externí odkaz:
https://doaj.org/article/86e102e8fd59464f8d82371e75111b70
Autor:
Mascha Fiona Dix, Peng Liu, Guoxin Cui, Francesco Della Valle, Valerio Orlando, Manuel Aranda
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68bc5aa135e08a653777f02853c372f
https://doi.org/10.3791/64817
https://doi.org/10.3791/64817