Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Valerio, Farfariello"'
Autor:
Valerio Farfariello, Dmitri V. Gordienko, Lina Mesilmany, Yasmine Touil, Emmanuelle Germain, Ingrid Fliniaux, Emilie Desruelles, Dimitra Gkika, Morad Roudbaraki, George Shapovalov, Lucile Noyer, Mathilde Lebas, Laurent Allart, Nathalie Zienthal-Gelus, Oksana Iamshanova, Franck Bonardi, Martin Figeac, William Laine, Jerome Kluza, Philippe Marchetti, Bruno Quesnel, Daniel Metzger, David Bernard, Jan B. Parys, Loïc Lemonnier, Natalia Prevarskaya
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Mitochondrial Ca2+ homeostasis is reported to influence cellular senescence. Here the authors show that TRPC3 limits senescence by inhibiting IP3R-mediated Ca2+ release and ER mitochondria Ca2+ transfer and that the downregulation of TRPC3 in stromal
Externí odkaz:
https://doaj.org/article/18e1a197a54f4fbebb56df91fdd44151
Autor:
Dorian V. Ziegler, David Vindrieux, Delphine Goehrig, Sara Jaber, Guillaume Collin, Audrey Griveau, Clotilde Wiel, Nadia Bendridi, Sophia Djebali, Valerio Farfariello, Natacha Prevarskaya, Léa Payen, Jacqueline Marvel, Sébastien Aubert, Jean-Michel Flaman, Jennifer Rieusset, Nadine Martin, David Bernard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Contacts between mitochondria and endoplasmatic reticulum (ER), and the transfer of calcium between them, have an important role in the regulation of cellular phenotypes, including senescence. Here the authors show that ITPR2 deficient mice display i
Externí odkaz:
https://doaj.org/article/7e2b02f88245449d9aaaf2f356575379
Autor:
Madelaine Magalì Audero, Tiago Miguel Amaral Carvalho, Federico Alessandro Ruffinatti, Thorsten Loeck, Maya Yassine, Giorgia Chinigò, Antoine Folcher, Valerio Farfariello, Samuele Amadori, Chiara Vaghi, Albrecht Schwab, Stephan J. Reshkin, Rosa Angela Cardone, Natalia Prevarskaya, Alessandra Fiorio Pla
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2572
Pancreatic Ductal Adenocarcinoma (PDAC) is characterized by an acidic microenvironment, which contributes to therapeutic failure. So far there is a lack of knowledge with respect to the role of the acidic microenvironment in the invasive process. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fdd3cf3c72e0c729dfcd52d2e82882
Autor:
Jamil Nehme, Lina Mesilmany, Valerio Farfariello, Marta Varela-Eirin, Yao Lin, Mariana Gaya Costa, Marc Seelen, Jan-Luuk Hillebrands, Harry van Goor, Raja Saab, Natacha Prevarskaya, Haidar Akl, Marco Demaria
Excessive amounts of Reactive oxygen species (ROS) lead to macromolecular damage and pathological sequelae. The mechanisms regulating oxidative stress-induced cell fate decision and their manipulation for improving repair remain poorly understood. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dd5908b3114751a454fe0903eecff0b
https://doi.org/10.21203/rs.3.rs-2672861/v1
https://doi.org/10.21203/rs.3.rs-2672861/v1
Autor:
Sonia Liberati, Maria Beatrice Morelli, Consuelo Amantini, Valerio Farfariello, Matteo Santoni, Alessandro Conti, Massimo Nabissi, Stefano Cascinu, Giorgio Santoni
Publikováno v:
Cells, Vol 3, Iss 1, Pp 112-128 (2014)
Herein we evaluate the involvement of the TRPV2 channel, belonging to the Transient Receptor Potential Vanilloid channel family (TRPVs), in development and progression of different tumor types. In normal cells, the activation of TRPV2 channels by gro
Externí odkaz:
https://doaj.org/article/e5f52898ff784f4d8081a89ed2370f5a
Autor:
Dimitri Henniquau, Nathan Schoonjans, Rédha Kassi, David Delcroix, Vanessa Avramovic, Valerio Farfariello, Pascal Mariot, Cappy, A., Alexis Vlandas, Christel Vanbesien, Virginie HOEL
Publikováno v:
GDR BioComp PhD Forum 2021
GDR BioComp PhD Forum 2021, GDR BioComp, Nov 2021, Grenoble (virtual), France
HAL
GDR BioComp PhD Forum 2021, GDR BioComp, Nov 2021, Grenoble (virtual), France
HAL
oral; National audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dc73955a44643b947e4d596f0c594995
https://hal.archives-ouvertes.fr/hal-03455151/document
https://hal.archives-ouvertes.fr/hal-03455151/document
Autor:
Clara Lewuillon, Aurélie Guillemette, Sofia Titah, Faruk Shaik, Nathalie Jouy, Ossama Labiad, Valerio Farfariello, Marie-Océane Laguillaumie, Thierry Idziorek, Adeline Barthélémy, Pauline Peyrouze, Céline Berthon, Mehmet Tarhan, Meyling Cheok, Bruno Quesnel, Loïc Lemonnier, Yasmine Touil
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (10), pp.5555. ⟨10.3390/ijms23105555⟩
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5555
International Journal of Molecular Sciences, 2022, 23 (10), pp.5555. ⟨10.3390/ijms23105555⟩
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5555
International audience; Acute myeloid leukemia (AML) is a hematological malignancy with a high risk of relapse. This issue is associated with the development of mechanisms leading to drug resistance that are not yet fully understood. In this context,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e75919012117eb6e2d7c997865c20ce
https://doi.org/10.3390/ijms23105555
https://doi.org/10.3390/ijms23105555
Publikováno v:
Reviews of physiology, biochemistry and pharmacology. 181
In the last three decades, a growing number of studies have implicated ion channels in all essential processes of prostate carcinogenesis, including cell proliferation, apoptosis, migration, and angiogenesis. The changes in the expression of individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cab6a3f4ee6686d3d2ee66063596d4d2
https://pubmed.ncbi.nlm.nih.gov/32737754
https://pubmed.ncbi.nlm.nih.gov/32737754
Publikováno v:
Reviews of Physiology, Biochemistry and Pharmacology ISBN: 9783030909192
In the last three decades, a growing number of studies have implicated ion channels in all essential processes of prostate carcinogenesis, including cell proliferation, apoptosis, migration, and angiogenesis. The changes in the expression of individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7de22a66c3bf1582e06b71954182311c
https://doi.org/10.1007/112_2020_22
https://doi.org/10.1007/112_2020_22
Publikováno v:
Cell Calcium. 69:4-18
Transient Receptor Potential (TRP) family mediate the influx of monovalent and/or divalent cations into cells in response to environmental stimuli. Pharmacological or genetic manipulations of TRP channels demonstrate that TRP channels influence cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb63c7595f79630d31b766026428841
https://doi.org/10.1016/j.ceca.2017.07.002
https://doi.org/10.1016/j.ceca.2017.07.002