Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Valerio, Chiurchiù"'
Autor:
Francesco Davide Naso, Krenare Bruqi, Valeria Manzini, Valerio Chiurchiù, Mara D’Onofrio, Ivan Arisi, Flavie Strappazzon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Breast Cancer (BC) is one of the most common tumours, and is known for its ability to develop resistance to chemotherapeutic treatments. Autophagy has been linked to chemotherapeutic response in several types of cancer, highlighting its cont
Externí odkaz:
https://doaj.org/article/18b95df482b34b7490e2fdf2c2275611
Autor:
Susanna De Stefano, Marta Tiberi, Illari Salvatori, Marco De Bardi, Juliette Gimenez, Mahsa Pirshayan, Viviana Greco, Giovanna Borsellino, Alberto Ferri, Cristiana Valle, Nicola B. Mercuri, Valerio Chiurchiù, Alida Spalloni, Patrizia Longone
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1241 (2024)
Hydrogen sulfide (H2S), a known inhibitor of the electron transport chain, is endogenously produced in the periphery as well as in the central nervous system, where is mainly generated by glial cells. It affects, as a cellular signaling molecule, man
Externí odkaz:
https://doaj.org/article/a83f3dfe6c3a423c9a4814ffa45ae7ab
Autor:
Riccardo Turchi, Francesca Sciarretta, Veronica Ceci, Marta Tiberi, Matteo Audano, Silvia Pedretti, Concetta Panebianco, Valentina Nesci, Valerio Pazienza, Alberto Ferri, Simone Carotti, Valerio Chiurchiù, Nico Mitro, Daniele Lettieri-Barbato, Katia Aquilano
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107713- (2023)
Summary: Friedreich’s ataxia (FA) is a neurodegenerative disease resulting from a mutation in the FXN gene, leading to mitochondrial frataxin deficiency. FA patients exhibit increased visceral adiposity, inflammation, and heightened diabetes risk,
Externí odkaz:
https://doaj.org/article/3c5148320c0b4e6788f36ea29e2d36bc
Autor:
Francesca Sciarretta, Veronica Ceci, Marta Tiberi, Fabio Zaccaria, Haoyun Li, Zhong-Yan Zhou, Qiyang Sun, Daniels Konja, Alessandro Matteocci, Anup Bhusal, Martina Verri, Diego Fresegna, Sara Balletta, Andrea Ninni, Claudia Di Biagio, Marco Rosina, Kyoungho Suk, Diego Centonze, Yu Wang, Valerio Chiurchiù, Katia Aquilano, Daniele Lettieri-Barbato
Publikováno v:
Molecular Metabolism, Vol 76, Iss , Pp 101783- (2023)
Objective: Accumulating evidence suggests that dysfunctional adipose tissue (AT) plays a major role in the risk of developing multiple sclerosis (MS), the most common immune-mediated and demyelinating disease of the central nervous system. However, t
Externí odkaz:
https://doaj.org/article/773476dec45d4371b40347909e199e36
Autor:
Valerio Chiurchiù
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11523 (2023)
Lipids are undoubtedly the major constituents of the cell membranes of all living organisms, and the most efficient source of energy [...]
Externí odkaz:
https://doaj.org/article/affaac72b4f04419b010f51289f2ad8d
Autor:
Alida Spalloni, Susanna de Stefano, Juliette Gimenez, Viviana Greco, Nicola B. Mercuri, Valerio Chiurchiù, Patrizia Longone
Publikováno v:
Cells, Vol 12, Iss 13, p 1691 (2023)
Ever since its presence was reported in the brain, the nature and role of hydrogen sulfide (H2S) in the Central Nervous System (CNS) have changed. Consequently, H2S has been elected as the third gas transmitter, along with carbon monoxide and nitric
Externí odkaz:
https://doaj.org/article/090c085ebd724276b003c35ac2b9660e
Autor:
Matti Hoch, Jannik Rauthe, Konstantin Cesnulevicius, Myron Schultz, David Lescheid, Olaf Wolkenhauer, Valerio Chiurchiù, Shailendra Gupta
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4342 (2023)
Lipid mediators are important regulators in inflammatory responses, and their biosynthetic pathways are targeted by commonly used anti-inflammatory drugs. Switching from pro-inflammatory lipid mediators (PIMs) to specialized pro-resolving (SPMs) is a
Externí odkaz:
https://doaj.org/article/d212c08523284f7d89470d90779d280a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3717 (2023)
Omega-3 (ω-3) polyunsaturated fatty acids, including docosahexaenoic acid (DHA), are involved in numerous biological processes and have a range of health benefits. DHA is obtained through the action of elongases (ELOVLs) and desaturases, among which
Externí odkaz:
https://doaj.org/article/5b0b2a5642574bde8d66ac892373b777
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Both the initiation and the resolution of inflammatory responses are governed by the sequential activation, migration, and control/suppression of immune cells at the site of injury. Bioactive lipids play a major role in the fine-tuning of this dynami
Externí odkaz:
https://doaj.org/article/8c9b52be948d4ead82a8151922b16622
Autor:
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D’Amelio, Nicola Biagio Mercuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Resolvins are endogenous lipids with pro-resolving activity. Here the authors find that rats overexpressing human α-synuclein show defects in dopamine signalling before dopamine cell loss, and that this is associated with low Resolvin D1 levels and
Externí odkaz:
https://doaj.org/article/4400ee42af354c6ca10e2b68760be226