Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Valerine C, Chunda"'
Autor:
Valerine C. Chunda, Fanny Fri Fombad, Chi Anizette Kien, Rene Ebai, Frederick Esofi, Anna Ning Ntuh, Emmanuel Ouam, Narcisse Victor Tchamatchoua Gandjui, Relindis Ekanya, Franck Nietcho, Lucy Cho Nchang, Chefor Magha, Abdel Jelil Njouendou, Peter Enyong, Achim Hoerauf, Samuel Wanji, Manuel Ritter
Publikováno v:
Frontiers in Tropical Diseases, Vol 5 (2024)
IntroductionMouse models of human filarial infections are not only urgently needed to investigate the biology of the nematodes and their modulation of the host’s immunity, but will also provide a platform to screen and test novel anti-filarial drug
Externí odkaz:
https://doaj.org/article/d2066627f88a44eca8ac60bfc4366a77
Autor:
Nicolas Pionnier, Julio Furlong-Silva, Stefano A. P. Colombo, Amy E. Marriott, Valerine C. Chunda, Bertrand L. Ndzeshang, Hanna Sjoberg, John Archer, Andrew Steven, Samuel Wanji, Mark J. Taylor, Joseph D. Turner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lymphatic filariasis and onchocerciasis are major neglected tropical diseases affecting over 90 million people worldwide with painful and profoundly disfiguring pathologies (such as lymphoedema or blindness). Type 2 inflammation is a hallmark of fila
Externí odkaz:
https://doaj.org/article/9dab80b843d444419be4b8c659f43b68
Autor:
Valerine C. Chunda, Manuel Ritter, Ayukenchengamba Bate, Narcisse V. T. Gandjui, Mathias E. Esum, Fanny F. Fombad, Abdel J. Njouendou, Patrick W. C. Ndongmo, Mark J. Taylor, Achim Hoerauf, Laura E. Layland, Joseph D. Turner, Samuel Wanji
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background Different immune mechanisms are capable of killing developmental stages of filarial nematodes and these mechanisms are also likely to vary between the primary and a challenge infection. However, the lack of a detailed analysis of
Externí odkaz:
https://doaj.org/article/a834dbf3f7084fdeaad7877732e1e6f2
Autor:
Anna Wiszniewsky, Laura E. Layland, Kathrin Arndts, Lisa M. Wadephul, Ruth S. E. Tamadaho, Dennis Borrero-Wolff, Valerine C. Chunda, Chi Anizette Kien, Achim Hoerauf, Samuel Wanji, Manuel Ritter
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite long-term mass drug administration programmes, approximately 220 million people are still infected with filariae in endemic regions. Several research studies have characterized host immune responses but a major obstacle for research on human
Externí odkaz:
https://doaj.org/article/dcf93911ea2a4f10bc20e763473f133b
Autor:
Nicolas P. Pionnier, Hanna Sjoberg, Valerine C. Chunda, Fanny F. Fombad, Patrick W. Chounna, Abdel J. Njouendou, Haelly M. Metuge, Bertrand L. Ndzeshang, Narcisse V. Gandjui, Desmond N. Akumtoh, Dizzle B. Tayong, Mark J. Taylor, Samuel Wanji, Joseph D. Turner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Here, the authors develop a mouse model of Loa loa that reflects human infections, including eosinophilia, and determine effects of ivermectin treatment.
Externí odkaz:
https://doaj.org/article/a61c0d045a0e4834baada450b5e69d0f
Autor:
Fanny Fri Fombad, Abdel Jelil Njouendou, Patrick Chounna Ndongmo, Manuel Ritter, Valerine C. Chunda, Haelly M. Metuge, Narcisse Victor T. Gandjui, Peter Enyong, Flobert Njiokou, Achim Hoerauf, Charles D. Mackenzie, Samuel Wanji
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Background Loiasis, an often-neglected tropical disease, is a threat to the success of lymphatic filariasis and onchocerciasis elimination programmes in rainforest areas of the central and western Africa. Its control and even its elimination
Externí odkaz:
https://doaj.org/article/285fd4507ee34efeb848305ea6b8b376
Autor:
Narcisse V T Gandjui, Abdel J Njouendou, Eric N Gemeg, Fanny F Fombad, Manuel Ritter, Chi A Kien, Valerine C Chunda, Jerome Fru, Mathias E Esum, Marc P Hübner, Peter A Enyong, Achim Hoerauf, Samuel Wanji
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0008513 (2021)
BackgroundInfections with Onchocerca volvulus nematodes remain a threat in Sub-Saharan Africa after three decades of ivermectin mass drug administration. Despite this effort, there is still an urgent need for understanding the parasite biology especi
Externí odkaz:
https://doaj.org/article/435ad9ae460441af8f7cde93934acdff
Autor:
Lontum B Ndzeshang, Fanny F Fombad, Abdel J Njouendou, Valerine C Chunda, Narcisse V T Gandjui, Desmond N Akumtoh, Patrick W N Chounna, Andrew Steven, Nicolas P Pionnier, Laura E Layland, Manuel Ritter, Achim Hoerauf, Mark J Taylor, Joseph D Turner, Samuel Wanji
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008415 (2020)
Basic and translational research on loiasis, a filarial nematode infection of medical importance, is impeded by a lack of suitable Loa loa infection models and techniques of obtaining and culturing life cycle stages. We describe the development of a
Externí odkaz:
https://doaj.org/article/f91d3d9e42af45d8b9318d4efe7077b4
Autor:
Hanna T Sjoberg, Nicolas Pionnier, Ghaith Aljayyoussi, Haelly M Metuge, Abdel J Njouendou, Valerine C Chunda, Fanny F Fombad, Dizzle B Tayong, Narcisse V T Gandjui, Desmond N Akumtoh, Patrick W N Chounna, Bertrand L Ndzeshang, Sophie Lachaud, Fetene Tekle, Ludo Quirynen, Marc Engelen, Benny Baeten, Andrew Steven, Stephen A Ward, Mark J Taylor, Samuel Wanji, Joseph D Turner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0006356 (2019)
The Onchocerca ochengi adult implant and Brugia malayi microfilariemic Severe-Combined Immunodeficient (SCID) mouse models are validated screens to measure macrofilaricidal and microfilaricidal activities of candidate onchocerciasis drugs. The purpos
Externí odkaz:
https://doaj.org/article/fe1c618c58354c30b115c91c359195be
Autor:
Nicolas, Pionnier, Julio, Furlong-Silva, Stefano A P, Colombo, Amy E, Marriott, Valerine C, Chunda, Bertrand L, Ndzeshang, Hanna, Sjoberg, John, Archer, Andrew, Steven, Samuel, Wanji, Mark J, Taylor, Joseph D, Turner
Publikováno v:
Frontiers in immunology. 13
Lymphatic filariasis and onchocerciasis are major neglected tropical diseases affecting over 90 million people worldwide with painful and profoundly disfiguring pathologies (such as lymphoedema or blindness). Type 2 inflammation is a hallmark of fila