Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Valeriia F. Tereshchenkova"'
Autor:
Nikita I. Zhiganov, Konstantin S. Vinokurov, Ruslan S. Salimgareev, Valeriia F. Tereshchenkova, Yakov E. Dunaevsky, Mikhail A. Belozersky, Elena N. Elpidina
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5743 (2024)
Serine peptidases (SPs) of the chymotrypsin S1A subfamily are an extensive group of enzymes found in all animal organisms, including insects. Here, we provide analysis of SPs in the yellow mealworm Tenebrio molitor transcriptomes and genomes datasets
Externí odkaz:
https://doaj.org/article/78e1330397a54eb98a0d42072b2bbfa5
Autor:
Valeriia F. Tereshchenkova, Irina Y. Filippova, Irina A. Goptar, Yakov E. Dunaevsky, Mikhail A. Belozersky, Elena N. Elpidina
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 579 (2022)
A detailed analysis of the complexes of proline-specific peptidases (PSPs) in the midgut transcriptomes of the larvae of agricultural pests Tenebrio molitor and Tribolium castaneum and in the genome of T. castaneum is presented. Analysis of the T. ca
Externí odkaz:
https://doaj.org/article/5a76ac86fee94660921cfe109d4b69ef
Autor:
Nikita I. Zhiganov, Valeriia F. Tereshchenkova, Brenda Oppert, Irina Y. Filippova, Nataliya V. Belyaeva, Yakov E. Dunaevsky, Mikhail A. Belozersky, Elena N. Elpidina
Publikováno v:
Data in Brief, Vol 38, Iss , Pp 107301- (2021)
Tenebrio molitor is an important coleopteran model insect and agricultural pest from the Tenebrionidae family. We used RNA-Seq transcriptome data from T. molitor to annotate trypsin-like sequences from the chymotrypsin S1 family of serine peptidases,
Externí odkaz:
https://doaj.org/article/20964f00be774169992a007dda67bc18
Autor:
Elena A. Dvoryakova, Maria A. Klimova, Tatiana R. Simonyan, Ivan A. Dombrovsky, Marina V. Serebryakova, Valeriia F. Tereshchenkova, Yakov E. Dunaevsky, Mikhail A. Belozersky, Irina Y. Filippova, Elena N. Elpidina
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7001 (2022)
Wheat gliadins contain a large amount of glutamine- and proline-rich peptides which are not hydrolyzed by human digestive peptidases and can cause autoimmune celiac disease and other forms of gluten intolerance in predisposed people. Peptidases that
Externí odkaz:
https://doaj.org/article/f15fc18ec5d145249c9bbbb93a3b46e4
Autor:
Irina Y. Filippova, Elena A. Dvoryakova, Nikolay I. Sokolenko, Tatiana R. Simonyan, Valeriia F. Tereshchenkova, Nikita I. Zhiganov, Yakov E. Dunaevsky, Mikhail A. Belozersky, Brenda Oppert, Elena N. Elpidina
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
New substrates with glutamine in the P1-position are introduced for the assay of peptidases from the C1 papain family, with a general formula of Glp-Phe-Gln-X, where Glp is pyroglutamyl and X is pNA (p-nitroanilide) or AMC (4-amino-7-methylcoumaride)
Externí odkaz:
https://doaj.org/article/32bf55c2fb8f49538df9f474f9ff196f
Autor:
Yakov E. Dunaevsky, Valeriia F. Tereshchenkova, Mikhail A. Belozersky, Irina Y. Filippova, Brenda Oppert, Elena N. Elpidina
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1603 (2021)
To date, there is no effective treatment for celiac disease (CD, gluten enteropathy), an autoimmune disease caused by gluten-containing food. Celiac patients are supported by a strict gluten-free diet (GFD). However, in some cases GFD does not negate
Externí odkaz:
https://doaj.org/article/2bd99dbd9d6d4d44800f7093e60cce59
Autor:
P. I. Akentyev, I. Yu. Filippova, Nikita I. Zhiganov, Valeriia F. Tereshchenkova, I. I. Gubaidullin, N. V. Belyaeva, D. G. Kozlov, Elena N. Elpidina
Publikováno v:
Applied Biochemistry and Microbiology. 57:579-585
Pseudoenzymes are homologs of active enzymes that have amino acid substitutions in the active center and, therefore, usually do not possess enzymatic activity. In this work, a recombinant proprotein (proSerPH122) of the homolog of serine peptidases o
Autor:
I. I. Gubaidullin, P. I. Akentyev, D. G. Kozlov, Elena N. Elpidina, Valeriia F. Tereshchenkova, Nikita I. Zhiganov
Publikováno v:
Biotekhnologiya. 36:78-86
A strain of the Komagataella kurtzmanii yeast, a producer of recombinant peptidase SerP38 from the yellow mealworm Tenebrio molitor, has been obtained. The level of the pro-enzyme secretion was 20-50 mg/L. It was shown that, during secretion in yeast
Autor:
Valeriia F. Tereshchenkova, Brenda Oppert, Elena N. Elpidina, Yakov E. Dunaevsky, Mikhail A. Belozersky, Irina Yu. Filippova
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1603, p 1603 (2021)
Pharmaceutics, Vol 13, Iss 1603, p 1603 (2021)
To date, there is no effective treatment for celiac disease (CD, gluten enteropathy), an autoimmune disease caused by gluten-containing food. Celiac patients are supported by a strict gluten-free diet (GFD). However, in some cases GFD does not negate
Autor:
Mikhail A. Belozersky, Brenda Oppert, Ya. E. Dunaevsky, Irina Yu. Filippova, Elena A. Dvoryakova, Konstantin Vinokurov, Elena N. Elpidina, Valeriia F. Tereshchenkova
Publikováno v:
Insect biochemistry and molecular biology. 140
We previously described the most highly expressed enzymes from the gut of the red flour beetle, Tribolium castaneum, as cathepsins L. In the present study, two C1 family-specific cysteine cathepsin L enzymes from the larval midgut were isolated and i