Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Valerie Z. Wall"'
Autor:
Sarah Alice Long, Virginia S. Muir, Britta E. Jones, Valerie Z. Wall, Alyssa Ylescupidez, Anne M. Hocking, Stephan Pribitzer, Jerill Thorpe, Bryce Fuchs, Alice E. Wiedeman, Megan Tatum, Katharina Lambert, Hannes Uchtenhagen, Cate Speake, Bernard Ng, Alexander T. Heubeck, Troy R. Torgerson, Adam K. Savage, Michael A. Maldonado, Neelanjana Ray, Vadim Khaychuk, Jinqi Liu, Peter S. Linsley, Jane H. Buckner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Exhausted CD8 T cells (TEX) are associated with worse outcome in cancer yet better outcome in autoimmunity. Building on our past findings of increased TIGIT+KLRG1+ TEX with teplizumab therapy in type 1 diabetes (T1D), in the absence of treatment we f
Externí odkaz:
https://doaj.org/article/848afa4859044e9fb280078686f378e7
Autor:
Valerie Z. Wall, Shelley Barnhart, Farah Kramer, Jenny E. Kanter, Anuradha Vivekanandan-Giri, Subramaniam Pennathur, Chiara Bolego, Jessica M. Ellis, Miguel A. Gijón, Michael J. Wolfgang, Karin E. Bornfeldt
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1174-1185 (2017)
Acyl-CoA thioesterase 7 (ACOT7) is an intracellular enzyme that converts acyl-CoAs to FFAs. ACOT7 is induced by lipopolysaccharide (LPS); thus, we investigated downstream effects of LPS-induced induction of ACOT7 and its role in inflammatory settings
Externí odkaz:
https://doaj.org/article/83f7d024471b48379c8e62abb1b69a7f
Autor:
Tomohiro Nishizawa, Jenny E. Kanter, Farah Kramer, Shelley Barnhart, Xia Shen, Anuradha Vivekanandan-Giri, Valerie Z. Wall, Jason Kowitz, Sridevi Devaraj, Kevin D. O’Brien, Subramaniam Pennathur, Jingjing Tang, Robert S. Miyaoka, Elaine W. Raines, Karin E. Bornfeldt
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 356-365 (2014)
Summary: Inflammatory activation of myeloid cells is accompanied by increased glycolysis, which is required for the surge in cytokine production. Although in vitro studies suggest that increased macrophage glucose metabolism is sufficient for cytokin
Externí odkaz:
https://doaj.org/article/32b0ea688622451eb44b45bbeb1adb0e
Autor:
Elizabeth M. Jaffee, Todd Armstrong, Valerie Z. Wall, Skylar Woolman, Kayla Cruz, Blake Scott, Brian Christmas, Tara M. Robinson, John-William Sidhom, Evanthia Roussos Torres, Bibhav Poudel, Hayley S. Ma
In cancers with tumor-infiltrating lymphocytes (TILs), monoclonal antibodies (mAbs) that block immune checkpoints such as CTLA-4 and PD-1/PD-L1 promote antitumor T-cell immunity. Unfortunately, most cancers fail to respond to single-agent immunothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a617d0ba2f7990a4e08436eb0a6826
https://doi.org/10.1158/2326-6066.c.6549304.v1
https://doi.org/10.1158/2326-6066.c.6549304.v1
Autor:
Elizabeth M. Jaffee, Todd Armstrong, Valerie Z. Wall, Skylar Woolman, Kayla Cruz, Blake Scott, Brian Christmas, Tara M. Robinson, John-William Sidhom, Evanthia Roussos Torres, Bibhav Poudel, Hayley S. Ma
Supplementary Table S1, Supplementary Figures S1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3366e8dae0103ee213e1f48bdee0eb
https://doi.org/10.1158/2326-6066.22540174
https://doi.org/10.1158/2326-6066.22540174
Autor:
Jessica M. Ellis, Chiara Bolego, Miguel A. Gijón, Shelley Barnhart, Michael J. Wolfgang, Jenny E. Kanter, Valerie Z. Wall, Subramaniam Pennathur, Anuradha Vivekanandan-Giri, Karin E. Bornfeldt, Farah Kramer
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1174-1185 (2017)
Acyl-CoA thioesterase 7 (ACOT7) is an intracellular enzyme that converts acyl-CoAs to FFAs. ACOT7 is induced by lipopolysaccharide (LPS); thus, we investigated downstream effects of LPS-induced induction of ACOT7 and its role in inflammatory settings
Autor:
Shelley Barnhart, Jenny E. Kanter, Valerie Z. Wall, Masami Shimizu-Albergine, Neeta Adhikari, Jennifer L. Hall, Karin E. Bornfeldt, Thomas N. Wight, Farah Kramer
Publikováno v:
JCI Insight. 3
Metabolic syndrome contributes to cardiovascular disease partly through systemic risk factors. However, local processes in the artery wall are becoming increasingly recognized to exacerbate atherosclerosis both in mice and humans. We show that arteri
Autor:
Todd D. Armstrong, Tara M. Robinson, Kayla Cruz, John-William Sidhom, Hayley S. Ma, Evanthia T. Roussos Torres, Elizabeth M. Jaffee, Skylar Woolman, Brian J. Christmas, Valerie Z. Wall, Blake Scott, Bibhav Poudel
Publikováno v:
Cancer immunology research. 7(3)
In cancers with tumor-infiltrating lymphocytes (TILs), monoclonal antibodies (mAbs) that block immune checkpoints such as CTLA-4 and PD-1/PD-L1 promote antitumor T-cell immunity. Unfortunately, most cancers fail to respond to single-agent immunothera
Autor:
Valerie Z. Wall, Karin E. Bornfeldt
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2175-2179
The prime function of the arterial smooth muscle cell (SMC) in adult individuals is to contract and relax, thereby regulating blood flow to target tissues. However, in several vascular diseases, arterial SMCs in the adult vessel undergo major changes
Autor:
Jenny E. Kanter, Kevin D. O’Brien, Elaine W. Raines, Anuradha Vivekanandan-Giri, Subramaniam Pennathur, R.S. Miyaoka, Jason Kowitz, Farah Kramer, Jingjing Tang, Sridevi Devaraj, Shelley Barnhart, Karin E. Bornfeldt, Valerie Z. Wall, Tomohiro Nishizawa, Xia Shen
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 356-365 (2014)
Summary: Inflammatory activation of myeloid cells is accompanied by increased glycolysis, which is required for the surge in cytokine production. Although in vitro studies suggest that increased macrophage glucose metabolism is sufficient for cytokin