Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valerie Willocq"'
Autor:
Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell re
Externí odkaz:
https://doaj.org/article/f3a9efe8e82843f4aa28ca11b29546aa
Autor:
Panayota Kolypetri, Shirong Liu, Laura M. Cox, Mai Fujiwara, Radhika Raheja, Dvora Ghitza, Anya Song, Dominique Daatselaar, Valerie Willocq, Howard L. Weiner
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102356- (2021)
Summary: Splenic Ly6Chigh monocytes are innate immune cells involved in the regulation of central nervous system-related diseases. Recent studies have reported the shaping of peripheral immune responses by the gut microbiome via mostly unexplored pat
Externí odkaz:
https://doaj.org/article/bd95a85eaa3743389ae962d12f675f6a
Autor:
Vaibhav P. Pai, Javier Cervera, Salvador Mafe, Valerie Willocq, Emma K. Lederer, Michael Levin
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Embryonic exposure to the teratogen nicotine results in brain defects, by disrupting endogenous spatial pre patterns necessary for normal brain size and patterning. Extending prior work in Xenopus laevis that showed that misexpression of ion channels
Externí odkaz:
https://doaj.org/article/587354ca633942958a0d48ad65f3fcdc
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The authors have previously shown that membrane voltage can influence embryonic patterning during development. Here, the authors computationally model how nicotine disrupts Xenopus embryogenesis by perturbing voltage gradients, and rescue nicotine-in
Externí odkaz:
https://doaj.org/article/e30cbd3fc0a9494ba626b09310562894
Autor:
Vaibhav P. Pai, Valerie Willocq, Emily J. Pitcairn, Joan M. Lemire, Jean-François Paré, Nian-Qing Shi, Kelly A. McLaughlin, Michael Levin
Publikováno v:
Biology Open, Vol 6, Iss 10, Pp 1445-1457 (2017)
Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the hea
Externí odkaz:
https://doaj.org/article/689a0e604839463a8dcd34890ee2ff83
Autor:
Galina Gabriely, Ana C. Anderson, Oleg Butovsky, Davide Mangani, Christian D Gauthier, Thais Garcias Moreira, Ana Maria Caetano Faria, David Correa Alves De Lima, Howard L. Weiner, Lydia Guo, Rafael M. Rezende, Brenda Naemi Nakagaki, Eduardo L C Lobo, Jeffrey A. Leibowitz, Laura M. Cox, Valerie Willocq, Mariana Assíria de Oliveira, Anya Song, Gopal Murugaiyan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The intestinal mucosa constitutes an environment of closely regulated immune cells. Dendritic cells (DC) interact with the gut microbiome and antigens and are important in maintaining gut homeostasis. Here, we investigate DC transcriptome, phenotype
Autor:
Tanuja Chitnis, Mariann Polgar-Turcsanyi, Anya Song, Stephanie K. Tankou, Caroline Wasén, Renxin Chu, Fyonn H Dhang, Laura M. Cox, Philip L. De Jager, Valerie Willocq, Mark C. Anderson, Shirong Liu, Amir-Hadi Maghzi, Howard L. Weiner, Bonnie I. Glanz, Brian C. Healy, Shahamat Tauhid, Rohit Bakshi
Publikováno v:
Ann Neurol
Objective This study was undertaken to investigate the gut microbiome in progressive multiple sclerosis (MS) and how it relates to clinical disease. Methods We sequenced the microbiota from healthy controls and relapsing-remitting MS (RRMS) and progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47c764bbb38104de3aa281cfe5b5014
https://europepmc.org/articles/PMC8132291/
https://europepmc.org/articles/PMC8132291/
Autor:
Kunal Jindal, Je-Hyuk Lee, Daniel Goodwin, Thomas C. Ferrante, Conor K. Camplisson, George M. Church, Shahar Alon, Eswar Prasad Ramachandran Iyer, Lauren Mifflin, Anne Cheng, Bruce A. Yankner, Richie E. Kohman, Edward S. Boyden, Songlei Liu, King Hwa Ling, Valerie Willocq, Sukanya Punthambaker, Katharina Meyer, John Aach, Jenny M. Tam, Asmamaw T Wassie, Fei Chen, Daniel Fürth, Anubhav Sinha, Andrew C. Pawlowski
Publikováno v:
Nucleic Acids Research
We present barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel insitu analyses (BOLORAMIS), a reverse transcription-free method for spatially-resolved, targeted, in situ RNA identification of single or multiple targets. BO
Autor:
Chantal Kuhn, Bruna K. Tatematsu, Rafael M. Rezende, Gustavo B. Menezes, Julia Mayrink, Howard L. Weiner, Brenda N. Nakagaki, Luisa Lemos, Thais G. Moreira, Selma Boulenouar, Shirong Liu, Valerie Willocq, Eduardo L.C. Lobo, Laura M. Cox, Fyonn Dhang, Juliana R. Lopes, Lydia Guo
Publikováno v:
SSRN Electronic Journal.
Oral tolerance (OT) plays a critical role in maintaining the gut homeostatic environment. OT is defective in mice lacking microbiota or gamma-delta T cells (γδ-/-). We found that γδ-/- mice have an altered microbiota, including a decrease in Rumi
Autor:
Lekha Pandit, Hrishikesh Lokhande, Chaithra Malli, Anitha D'Cunha, Timothy Rooney, Tanuja Chitnis, Laura M. Cox, Valerie Willocq, Shrishti Saxena
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo understand the role of gut microbiome in influencing the pathogenesis of neuromyelitis optica spectrum disorders (NMOSDs) among patients of south Indian origin.MethodsIn this case-control study, stool and blood samples were collected from