Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Valerie W Hu"'
Autor:
Thanit Saeliw, Songphon Kanlayaprasit, Surangrat Thongkorn, Kwanjira Songsritaya, Bumpenporn Sanannam, Depicha Jindatip, Valerie W. Hu, Tewarit Sarachana
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract LINE-1 and Alu retrotransposons are components of the human genome and have been implicated in many human diseases. These elements can influence human transcriptome plasticity in various mechanisms. Chimeric transcripts derived from LINE-1 a
Externí odkaz:
https://doaj.org/article/23124bb14f064ff09c0ed236f712081c
Autor:
Songphon Kanlayaprasit, Thanit Saeliw, Surangrat Thongkorn, Pawinee Panjabud, Kasidit Kasitipradit, Pattanachat Lertpeerapan, Kwanjira Songsritaya, Wasana Yuwattana, Thanawin Jantheang, Depicha Jindatip, Valerie W. Hu, Takako Kikkawa, Noriko Osumi, Tewarit Sarachana
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-29 (2024)
Abstract Background Recent studies have shown that prenatal BPA exposure altered the transcriptome profiles of autism-related genes in the offspring’s hippocampus, disrupting hippocampal neuritogenesis and causing male-specific deficits in learning
Externí odkaz:
https://doaj.org/article/d54cfde5fe354edf91eec46d0667755d
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67569 (2013)
Most genome linkage scans for autism spectrum disorders (ASDs) have failed to be replicated. Recently, a new ASD phenotypic sub-classification method was developed which employed cluster analyses of severity scores from the Autism Diagnostic Intervie
Externí odkaz:
https://doaj.org/article/5128c82d03a04e2fb71cf41ad397c745
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19067 (2011)
The heterogeneity of symptoms associated with autism spectrum disorders (ASDs) has presented a significant challenge to genetic analyses. Even when associations with genetic variants have been identified, it has been difficult to associate them with
Externí odkaz:
https://doaj.org/article/cf16c26f80954c9bba8c0f54b79f1a79
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17116 (2011)
Autism, a pervasive neurodevelopmental disorder manifested by deficits in social behavior and interpersonal communication, and by stereotyped, repetitive behaviors, is inexplicably biased towards males by a ratio of ∼4∶1, with no clear understand
Externí odkaz:
https://doaj.org/article/fa77cbe756304934a0d5bdc6e8814b88
Autor:
Valerie W Hu, AnhThu Nguyen, Kyung Soon Kim, Mara E Steinberg, Tewarit Sarachana, Michele A Scully, Steven J Soldin, Truong Luu, Norman H Lee
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5775 (2009)
Despite the identification of numerous autism susceptibility genes, the pathobiology of autism remains unknown. The present "case-control" study takes a global approach to understanding the molecular basis of autism spectrum disorders based upon larg
Externí odkaz:
https://doaj.org/article/ae0c22c538494f549963c948e78fa68e
Autor:
Anchalee Prasansuklab, Suporn Sukjamnong, Atsadang Theerasri, Valerie W. Hu, Tewarit Sarachana, Tewin Tencomnao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Glutamate-induced neurotoxicity in the HT22 mouse hippocampal neuronal cell line has been recognized as a valuable cell model for the study of neurotoxicity associated with neurodegenerative diseases including Alzheimer’s disease (AD). How
Externí odkaz:
https://doaj.org/article/c23f36db5fb64808b29a30d4bd4250b6
Autor:
Surangrat Thongkorn, Songphon Kanlayaprasit, Kasidit Kasitipradit, Pattanachat Lertpeerapan, Pawinee Panjabud, Valerie W. Hu, Depicha Jindatip, Tewarit Sarachana
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-27 (2023)
Highlights Prenatal BPA exposure altered the transcriptome profiles of genes associated with ASD in the offspring hippocampus through several ASD-related transcription factors, including AR and ESR1, in a sex-dependent manner. In addition to the know
Externí odkaz:
https://doaj.org/article/6f2c823640a247839c9bf8db0dc04ff1
Autor:
Valerie W Hu
This book focuses on the emerging and expanding areas of research on ASD and their potential to lead to better diagnosis and more effective therapies. These areas include innovative and integrative approaches to genetic/genomic analyses and investiga
Autor:
Valerie W. Hu, Chongfeng Bi
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Autism spectrum disorder (ASD) describes a collection of neurodevelopmental disorders characterized by core symptoms that include social communication deficits and repetitive, stereotyped behaviors often coupled with restricted interests. Primary cha
Externí odkaz:
https://doaj.org/article/fba8c334260442ea94012c0b0187fadd