Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Valerie W Hu"'
Autor:
Thanit Saeliw, Songphon Kanlayaprasit, Surangrat Thongkorn, Kwanjira Songsritaya, Bumpenporn Sanannam, Depicha Jindatip, Valerie W. Hu, Tewarit Sarachana
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract LINE-1 and Alu retrotransposons are components of the human genome and have been implicated in many human diseases. These elements can influence human transcriptome plasticity in various mechanisms. Chimeric transcripts derived from LINE-1 a
Externí odkaz:
https://doaj.org/article/23124bb14f064ff09c0ed236f712081c
Autor:
Songphon Kanlayaprasit, Thanit Saeliw, Surangrat Thongkorn, Pawinee Panjabud, Kasidit Kasitipradit, Pattanachat Lertpeerapan, Kwanjira Songsritaya, Wasana Yuwattana, Thanawin Jantheang, Depicha Jindatip, Valerie W. Hu, Takako Kikkawa, Noriko Osumi, Tewarit Sarachana
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-29 (2024)
Abstract Background Recent studies have shown that prenatal BPA exposure altered the transcriptome profiles of autism-related genes in the offspring’s hippocampus, disrupting hippocampal neuritogenesis and causing male-specific deficits in learning
Externí odkaz:
https://doaj.org/article/d54cfde5fe354edf91eec46d0667755d
Autor:
Anchalee Prasansuklab, Suporn Sukjamnong, Atsadang Theerasri, Valerie W. Hu, Tewarit Sarachana, Tewin Tencomnao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Glutamate-induced neurotoxicity in the HT22 mouse hippocampal neuronal cell line has been recognized as a valuable cell model for the study of neurotoxicity associated with neurodegenerative diseases including Alzheimer’s disease (AD). How
Externí odkaz:
https://doaj.org/article/c23f36db5fb64808b29a30d4bd4250b6
Autor:
Valerie W Hu
This book focuses on the emerging and expanding areas of research on ASD and their potential to lead to better diagnosis and more effective therapies. These areas include innovative and integrative approaches to genetic/genomic analyses and investiga
Autor:
Surangrat Thongkorn, Songphon Kanlayaprasit, Kasidit Kasitipradit, Pattanachat Lertpeerapan, Pawinee Panjabud, Valerie W. Hu, Depicha Jindatip, Tewarit Sarachana
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-27 (2023)
Highlights Prenatal BPA exposure altered the transcriptome profiles of genes associated with ASD in the offspring hippocampus through several ASD-related transcription factors, including AR and ESR1, in a sex-dependent manner. In addition to the know
Externí odkaz:
https://doaj.org/article/6f2c823640a247839c9bf8db0dc04ff1
Autor:
Thanit Saeliw, Tiravut Permpoon, Nutta Iadsee, Tewin Tencomnao, Valerie W. Hu, Tewarit Sarachana, Daniel Green, Chanachai Sae-Lee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Long interspersed nucleotide element-1 (LINE-1) and Alu elements are retrotransposons whose abilities cause abnormal gene expression and genomic instability. Several studies have focused on DNA methylation profiling of gene regions, but the
Externí odkaz:
https://doaj.org/article/cabcf2fae4d74a26809adfc79dea6b10
Autor:
Angela G. Maggio, Henry T. Shu, Benjamin I. Laufer, Chongfeng Bi, Yinglei Lai, Janine M. LaSalle, Valerie W. Hu
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Environmental exposures to endocrine disrupting compounds (EDCs) such as the organochlorines have been linked with various diseases including neurodevelopmental disorders. Autism spectrum disorder (ASD) is a highly complex neurodevelopmental disorder
Externí odkaz:
https://doaj.org/article/4049fdc39ba74dbcb2ae582372ba4402
Autor:
Surangrat Thongkorn, Songphon Kanlayaprasit, Pawinee Panjabud, Thanit Saeliw, Thanawin Jantheang, Kasidit Kasitipradit, Suthathip Sarobol, Depicha Jindatip, Valerie W. Hu, Tewin Tencomnao, Takako Kikkawa, Tatsuya Sato, Noriko Osumi, Tewarit Sarachana
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Our recent study has shown that prenatal exposure to bisphenol A (BPA) altered the expression of genes associated with autism spectrum disorder (ASD). In this study, we further investigated the effects of prenatal BPA exposure on ASD-related
Externí odkaz:
https://doaj.org/article/61335a794d654c10913bb9e06dc44170
Autor:
Valerie W. Hu, Chongfeng Bi
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Autism spectrum disorder (ASD) describes a collection of neurodevelopmental disorders characterized by core symptoms that include social communication deficits and repetitive, stereotyped behaviors often coupled with restricted interests. Primary cha
Externí odkaz:
https://doaj.org/article/fba8c334260442ea94012c0b0187fadd
Autor:
Thanit Saeliw, Chayanin Tangsuwansri, Surangrat Thongkorn, Weerasak Chonchaiya, Kanya Suphapeetiporn, Apiwat Mutirangura, Tewin Tencomnao, Valerie W. Hu, Tewarit Sarachana
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-19 (2018)
Abstract Background Alu elements are a group of repetitive elements that can influence gene expression through CpG residues and transcription factor binding. Altered gene expression and methylation profiles have been reported in various tissues and c
Externí odkaz:
https://doaj.org/article/97dbde3d20104253b4439b5cf861c368