Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Valerie Tokars"'
Publikováno v:
Cells, Vol 11, Iss 1, p 169 (2022)
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease with a similar clinical presentation and progression to idiopathic Parkinson’s disease, and common variation is linked to disease risk. Recapitulation of the genotype in
Externí odkaz:
https://doaj.org/article/98d70a4746ee4da1a208834b5a483f04
Autor:
David Gius, Angela E. Dean, Songhua Quan, Elizabeth L. Tran, Valerie Tokars, Yucheng Gao, Yueming Zhu
Publikováno v:
International Journal of Biological Sciences
Manganese superoxide dismutase (MnSOD) acetylation (Ac) has been shown to be a key post-translational modification important in the regulation of detoxification activity in various disease models. We have previously demonstrated that MnSOD lysine-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef588e170fb10132c09a709b549d0bd
http://europepmc.org/articles/PMC8040469
http://europepmc.org/articles/PMC8040469
Publikováno v:
Trends in biochemical sciences. 47(3)
Variations in the LRRK2 gene represent one of the strongest genetic factors for Parkinson's disease (PD). It has become clear that structural knowledge of the encoded large multidomain LRRK2 protein will cast light on its biological function. The new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84df6bc70779f24896c37923065da79
https://pubmed.ncbi.nlm.nih.gov/34756665
https://pubmed.ncbi.nlm.nih.gov/34756665
Autor:
Jeremy V. Mathews, Yue Cao, Huiping Liu, Brian Wray, Yuzhi Jia, Valery Adorno-Cruz, Erika K. Ramos, Lamiaa El-Shennawy, Rokana Taftaf, Megan Manu, Massimo Cristofanilli, Andrew D. Hoffmann, Shanshan Zhang, Chia-Feng Tsai, Nurmaa Dashzeveg, Youbin Zhang, Dhwani Patel, Matthew J. Schipma, Liu Xia, David Scholten, Priyam Patel, Yang Shen, Tujin Shi, Valerie Tokars, Emma J. Schuster
Publikováno v:
SSRN Electronic Journal.
Tumor-initiating cells with reprogramming plasticity and/or de-differentiation attributes have been thought to initiate primary tumor development as well as to regenerate secondary tumors in metastatic organs; however, the molecular mechanisms are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb3c2e22a531e74735888f40a2b185e9
https://doi.org/10.2139/ssrn.3871398
https://doi.org/10.2139/ssrn.3871398
Autor:
Suchitra Swaminathan, Huiping Liu, Carolina Ostiguin, Jan Wysocki, Thomas J. Hope, Daniel Batlle, Zihao Yu, Alexis R. Demonbreun, Lamiaa El-Shennawy, Chengsheng Mao, Deyu Fang, Nurmaa Dashzeveg, Michael G. Ison, Yuan Luo, Yang Shen, Kevin Furlong, Vlad Nicolaescu, Andrew D. Hoffmann, Paul J. Mehl, Valerie Tokars, Hui Zhang, Lin Li, Glenn Randall, Young Kwang Chae, Yuzhi Jia
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19) with innate and adaptive immune response triggered in such patients by viral antigens. Both convalescent plasma and engineered high affini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ae32b37582383b87101e18915cab07
https://doi.org/10.1101/2020.12.03.407031
https://doi.org/10.1101/2020.12.03.407031
