Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Valerie Taly"'
Early detection of pancreatic cancer by liquid biopsy 'PANLIPSY': a french nation-wide study project
Autor:
Thomas Bardol, Antoine M. Dujon, Valerie Taly, Catherine Dunyach-Remy, Jean-Philippe Lavigne, Bruno Costa-Silva, Keerthi Kurma, Zahra Eslami-S, Laure Cayrefourcq, Cindy Canivet, Fabrice Muscari, Barbara Bournet, Catherine Alix-Panabières
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. This poor prognosis i
Externí odkaz:
https://doaj.org/article/44c5029baad6433f9786b21635522367
Autor:
Geoffroy Poulet, Jean-Sébastien Hulot, Anne Blanchard, Damien Bergerot, Wenjin Xiao, Frederic Ginot, Audrey Boutonnet-Rodat, Abdelli Justine, Guillaume Beinse, Vanna Geromel, Laurence Pellegrina, Michel Azizi, Pierre Laurent-Puig, Leonor Benhaim, Valerie Taly
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In the last decade, clinical studies have investigated the clinical relevance of circulating cell-free-DNA (ccfDNA) as a diagnostic and prognosis tool in various diseases including cancers. However, limited knowledge on ccfDNA biology restra
Externí odkaz:
https://doaj.org/article/1023306ad2ac4a30b7b4267a107f21d3
Autor:
Geoffroy Poulet, Fanny Garlan, Sonia Garrigou, Eleonora Zonta, Leonor Benhaim, Marie-Jennifer Carrillon, Audrey Didelot, Delphine Le Corre, Claire Mulot, Philippe Nizard, Frederic Ginot, Audrey Boutonnet-Rodat, Helene Blons, Jean-Baptiste Bachet, Julien Taïeb, Aziz Zaanan, Vanna Geromel, Laurence Pellegrina, Pierre Laurent-Puig, Shu-Fang Wang-Renault, Valerie Taly
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Background: Cellular-cell free-DNA (ccfDNA) is being explored as a diagnostic and prognostic tool for various diseases including cancer. Beyond the evaluation of the ccfDNA mutational status, its fragmentation has been investigated as a potential can
Externí odkaz:
https://doaj.org/article/e638b9a1871d45d79e5c8adad9bc53a5
Publikováno v:
Micromachines, Vol 10, Iss 4, p 265 (2019)
Traditional two-dimensional (2D) cell culture models are limited in their ability to reproduce human structures and functions. On the contrary, three-dimensional (3D) microtissues have the potential to permit the development of new cell-based assays
Externí odkaz:
https://doaj.org/article/28bfb57ca4894498a7416ffc2f2bde11
Autor:
Olivier Caliez, Daniel Pietrasz, Feryel Ksontini, Solène Doat, Jean-Marc Simon, Jean-Christophe Vaillant, Valerie Taly, Pierre Laurent-Puig, Jean-Baptiste Bachet
Publikováno v:
Digestive and Liver Disease
Digestive and Liver Disease, 2022, 54 (10), pp.1428-1436. ⟨10.1016/j.dld.2022.01.126⟩
Digestive and Liver Disease, 2022, 54 (10), pp.1428-1436. ⟨10.1016/j.dld.2022.01.126⟩
International audience; Background: prognostic biomarkers could be useful to better select patients with borderline resectable (BR) or locally advanced (LA) pancreatic adenocarcinoma (PA) for chemoradiotherapy (CRT) and/or secondary resection.Aims: T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2b92ba8e8776a73dcbf7dd7f3858ba
https://doi.org/10.1016/j.dld.2022.01.126
https://doi.org/10.1016/j.dld.2022.01.126
Development and validation of a RNAseq signature for prognostic stratification in endometrial cancer
Autor:
Guillaume Beinse, Marie-Aude Le Frere Belda, Pierre-Alexandre Just, Nahina Bekmezian, Meriem Koual, Simon Garinet, Karen Leroy, Franck Letourneur, Adèle Lusson, Claire Mulot, Delphine Le Corre, Marie Metairie, Nicolas Delanoy, Helene Blons, Claire Gervais, Catherine Durdux, Charles Chapron, François Goldwasser, Benoit Terris, Cecile Badoual, Valerie Taly, Pierre Laurent-Puig, Bruno Borghese, Anne-Sophie Bats, Jérôme Alexandre
Publikováno v:
Gynecologic Oncology
Gynecologic Oncology, 2022, 164 (3), pp.596-606. ⟨10.1016/j.ygyno.2022.01.005⟩
Gynecologic Oncology, 2022, 164 (3), pp.596-606. ⟨10.1016/j.ygyno.2022.01.005⟩
International audience; Background: Despite recent advances in endometrial carcinoma (EC) molecular characterization, its prognostication remains challenging. We aimed to assess whether RNAseq could stratify EC patient prognosis beyond current classi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622e80122550b0b0831b1679db44cec1
https://doi.org/10.1016/j.ygyno.2022.01.005
https://doi.org/10.1016/j.ygyno.2022.01.005
Publikováno v:
Lab on a Chip
Lab on a Chip, In press, ⟨10.1039/d2lc00220e⟩
Lab on a Chip, In press, ⟨10.1039/d2lc00220e⟩
International audience; Single cell multimodal analysis is at the frontier of single cell research: it defines the roles and functions of distinct cell types through simultaneous analysis to provide unprecedented insight into cellular processes. Curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c66320a357ec704566459d34ff8e1b
https://doi.org/10.1039/d2lc00220e
https://doi.org/10.1039/d2lc00220e
Autor:
Aziz Zaanan, Valerie Taly, Frederic Di Fiore, Julien Taieb, Hélène Blons, Claire Mulot, Geraldine Perkins, Pierre Michel, Nasrin Sarafan-Vasseur, Audrey Didelot, Nathalie Siauve, David Sefrioui, Pierre Laurent-Puig, Fanny Garlan
Supplementary Figure 1. Impact of baseline ctDNA concentration on overall survival (OS) in the subgroup of patients included before the 1st line of treatment (n=68).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cb3418a4413147fba01be00aab364e
https://doi.org/10.1158/1078-0432.22468814
https://doi.org/10.1158/1078-0432.22468814
Autor:
Valerie Taly, J. Brian Hutchison, Valérie Boige, Bruno Landi, Jean-François Emile, Olivier Bouché, Darren R. Link, Xinyu Li, Zakaria El Harrak, Thevy Hor, Delphine Le Corre, Preethi Srinivasan, Jeff Olson, Rachel Rowell, Karla Perez-Toralla, Philippe Nizard, Steve K. Kotsopoulos, Corinne Normand, Deniz Pekin, Pierre Laurent-Puig
Purpose:KRAS mutations are predictive of nonresponse to anti-EGFR therapies in metastatic colorectal cancer (mCRC). However, only 50% of nonmutated patients benefit from them. KRAS-mutated subclonal populations nondetectable by conventional methods h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0f9e9bfb66641d2031ef4b3546eeb4
https://doi.org/10.1158/1078-0432.c.6524613.v1
https://doi.org/10.1158/1078-0432.c.6524613.v1
Autor:
Valerie Taly, J. Brian Hutchison, Valérie Boige, Bruno Landi, Jean-François Emile, Olivier Bouché, Darren R. Link, Xinyu Li, Zakaria El Harrak, Thevy Hor, Delphine Le Corre, Preethi Srinivasan, Jeff Olson, Rachel Rowell, Karla Perez-Toralla, Philippe Nizard, Steve K. Kotsopoulos, Corinne Normand, Deniz Pekin, Pierre Laurent-Puig
Supplemental Materials. Supplemental Table 1: Patient mutational status and agreement between qPCR, dPCR and sequencing results. Supplemental Table 2: Analysis of different tissue samples coming from the same patient. Supplemental Figure 1: Fraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4e6d8fd442e81ff370b92c16f4e370
https://doi.org/10.1158/1078-0432.22460850.v1
https://doi.org/10.1158/1078-0432.22460850.v1